Results 81 to 90 of about 601,539 (340)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Advancing Stability in Robot Manipulators: A Review of Recent Progress and Parameters

Engineering Reports
In this review, we present an overview of the current state‐of‐the‐art in robotics while emphasizing stability and control aspects with pragmatic consideration over robotic manipulators.
Shabnom Mustary, Mohammod Abul Kashem, Jannatul Mawya Sony, Nayem Hossain, Mohammad Asaduzzaman Chowdhury   +4 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Compliance and Force Control for Computer Controlled Manipulators

IEEE Transactions on Systems, Man and Cybernetics, 1981
Compliant motion of a manipulator occurs when the manipulator position is constrained by the task geometry. Compliant motion may be produced either by a passive mechanical compliance built in to the manipulator, or by an active compliance implemented in ...
M. T. Mason
semanticscholar   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Analysis of Distributed Dynamic Loads Induced by the Own Mass of Manipulator Links and Their Visualization on Interactive 3D Computer Models

Robotics
This study proposes an approach to 3D modeling of spatial manipulators in the Maple 2023 software environment. Algorithms and program codes have been developed to create computer 3D models of manipulators controlled by generalized coordinates.
Muratulla Utenov, Tarek Sobh, Yerbol Temirbekov, Saltanat Zhilkibayeva, Sarosh Patel, Dauren Baltabay, Zhadyra Zhumasheva   +6 more
doaj   +1 more source

Differential Kinematics Of Contemporary Industrial Robots

International Journal of Applied Mechanics and Engineering, 2014
The paper presents a simple method of avoiding singular configurations of contemporary industrial robot manipulators of such renowned companies as ABB, Fanuc, Mitsubishi, Adept, Kawasaki, COMAU and KUKA.
T. Szkodny
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Integrated Intelligent Control of Redundant Degrees-of-Freedom Manipulators via the Fusion of Deep Reinforcement Learning and Forward Kinematics Models

Machines
Redundant degree-of-freedom (DOF) manipulators offer increased flexibility and are better suited for obstacle avoidance, yet precise control of these systems remains a significant challenge.
Yushuo Chen, Shijie Su, Kai Ni, Cunjun Li   +3 more
doaj   +1 more source

Control of two-link flexible manipulators via generalized canonical transformation [PDF]

, 2004
Since the two-link flexible manipulator is an underactuated system which provide a challenge to control engineers and researchers. In order to control this kind of systems more effectively, many new control theories and methods are explored to use to ...
Fujimoto, Kenji, Hayakawa, Yoshikazu, Bo, Xu   +2 more
core   +1 more source