Results 61 to 70 of about 42,913 (289)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Electronic MarketsAbstractHuman behaviour is affected by architecture, including how online user interfaces are designed. The purpose of this article is to provide insights into the regulation of behaviour modification by the design of choice architecture in light of the European Union data protection law (GDPR) and marketing law (UCPD). It has become popular to use the
openaire +1 more source
Extension versus Bending for Continuum Robots
International Journal of Advanced Robotic Systems, 2008 In this paper, we analyze the capabilities of a novel class of continuous-backbone ("continuum") robots. These robots are inspired by biological "trunks, and tentacles". However, the capabilities of established continuum robot designs,
George Grimes +3 more
doaj
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
A New Task-Space Neural Nonlinear Control Approach for Robotic Manipulators Under Joint Constraints
IEEE AccessRobotic manipulators are nonlinear systems with multi-input multi-output (MIMO) structures, uncertainties, and time-varying dynamical prospects. Unexpected influences of internal and external disturbances along with physical constraints in complicated ...
Nguyen Tran Minh Nguyet, Dang Xuan Ba
doaj +1 more source
Analytical Method for Determination of Internal Forces of Mechanisms and Manipulators
Robotics, 2018 This paper presents a theory for the analytical determination of internal forces in the links of planar linkage mechanisms and manipulators with statically determinate structures, considering the distributed dynamic loads.
Muratulla Utenov +4 more
doaj +1 more source
Technologies of the Future: Smart Production in Industry
Вестник Российского экономического университета имени Г. В. Плеханова, 2020 In line with global trends of virtual production within the frames of the 4-th industrial revolution concept industrial enterprises facing new challenges and objectives have to transform their production processes in order to support competitiveness ...
S. B. Baurina
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Robotic Arm Control Algorithm Based on Stereo Vision Using RoboRealm Vision
Advances in Electrical and Computer Engineering, 2015 The goal of this paper is to present a stereo computer vision algorithm intended to control a robotic arm. Specific points on the robot joints are marked and recognized in the software. Using a dedicated set of mathematic equations, the movement of the
SZABO, R., GONTEAN, A.
doaj +1 more source