Results 61 to 70 of about 88,392 (279)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Manipulating Representations [PDF]

open access: yesBiosemiotics, 2011
The present paper proposes a definition for the complex polysemic concepts of consciousness and awareness (in humans as well as in other species), and puts forward the idea of a progressive ontological development of consciousness from a state of 'childhood' awareness, in order to explain that humans are not only able to manipulate objects, but also ...
openaire   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

How many candidates are needed to make elections hard to manipulate?

open access: yes, 2003
In multiagent settings where the agents have different preferences, preference aggregation is a central issue. Voting is a general method for preference aggregation, but seminal results have shown that all general voting protocols are manipulable.
Jerome Lang   +4 more
core   +4 more sources

Technologies of the Future: Smart Production in Industry

open access: yesВестник Российского экономического университета имени Г. В. Плеханова, 2020
In line with global trends of virtual production within the frames of the 4-th industrial revolution concept industrial enterprises facing new challenges and objectives have to transform their production processes in order to support competitiveness ...
S. B. Baurina
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Reinstating Combinatorial Protections for Manipulation and Bribery in Single-Peaked and Nearly Single-Peaked Electorates

open access: yes, 2015
Understanding when and how computational complexity can be used to protect elections against different manipulative actions has been a highly active research area over the past two decades.
Larson, Kate, Menon, Vijay
core   +1 more source

Extension versus Bending for Continuum Robots

open access: yesInternational Journal of Advanced Robotic Systems, 2008
In this paper, we analyze the capabilities of a novel class of continuous-backbone ("continuum") robots. These robots are inspired by biological "trunks, and tentacles". However, the capabilities of established continuum robot designs,
George Grimes   +3 more
doaj  

A New Task-Space Neural Nonlinear Control Approach for Robotic Manipulators Under Joint Constraints

open access: yesIEEE Access
Robotic manipulators are nonlinear systems with multi-input multi-output (MIMO) structures, uncertainties, and time-varying dynamical prospects. Unexpected influences of internal and external disturbances along with physical constraints in complicated ...
Nguyen Tran Minh Nguyet, Dang Xuan Ba
doaj   +1 more source

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