Results 71 to 80 of about 42,913 (289)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Advancing Stability in Robot Manipulators: A Review of Recent Progress and Parameters

Engineering Reports
In this review, we present an overview of the current state‐of‐the‐art in robotics while emphasizing stability and control aspects with pragmatic consideration over robotic manipulators.
Shabnom Mustary, Mohammod Abul Kashem, Jannatul Mawya Sony, Nayem Hossain, Mohammad Asaduzzaman Chowdhury   +4 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Analysis of Distributed Dynamic Loads Induced by the Own Mass of Manipulator Links and Their Visualization on Interactive 3D Computer Models

Robotics
This study proposes an approach to 3D modeling of spatial manipulators in the Maple 2023 software environment. Algorithms and program codes have been developed to create computer 3D models of manipulators controlled by generalized coordinates.
Muratulla Utenov, Tarek Sobh, Yerbol Temirbekov, Saltanat Zhilkibayeva, Sarosh Patel, Dauren Baltabay, Zhadyra Zhumasheva   +6 more
doaj   +1 more source

Differential Kinematics Of Contemporary Industrial Robots

International Journal of Applied Mechanics and Engineering, 2014
The paper presents a simple method of avoiding singular configurations of contemporary industrial robot manipulators of such renowned companies as ABB, Fanuc, Mitsubishi, Adept, Kawasaki, COMAU and KUKA.
T. Szkodny
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Integrated Intelligent Control of Redundant Degrees-of-Freedom Manipulators via the Fusion of Deep Reinforcement Learning and Forward Kinematics Models

Machines
Redundant degree-of-freedom (DOF) manipulators offer increased flexibility and are better suited for obstacle avoidance, yet precise control of these systems remains a significant challenge.
Yushuo Chen, Shijie Su, Kai Ni, Cunjun Li   +3 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Robot Manipulators [PDF]

, 2010
Robot manipulators are developing more in the direction of industrial robots than of human workers. Recently, the applications of robot manipulators are spreading their focus, for example Da Vinci as a medical robot, ASIMO as a humanoid robot and so on ...

core   +1 more source