Results 231 to 240 of about 44,027 (268)

RECOMBINANT HUMAN MANNAN-BINDING LECTIN

1999
The present invention relates to methods of producing and/or isolating MEL compositions. In particular the inven­tion relates to methods of producing and/or isolating novel recombinant human MEL preparations with high similarity to natural human MEL.
Vorup-Jensen, Thomas, Thiel, S., Jensenius, J.C.   +2 more
openaire   +2 more sources

Single-nucleotide polymorphisms in porcine mannan-binding lectin A

Immunogenetics, 2006
The MBL1 and MBL2 genes encode mannan-binding lectins (MBL) A and C, respectively, that are collagenous lectins (collectins) produced mainly by the liver. Several single-nucleotide polymorphisms (SNPs) in the human MBL2 gene are responsible for various innate immune dysfunctions due to abnormal structure or expression of human MBL-C.
Lillie, B., Keirstead, N., Squires, E., Hayes, M.   +3 more
openaire   +4 more sources

Mannan-binding lectin deficiency augments hepatic endoplasmic reticulum stress through IP3R-controlled calcium release.

Cell Calcium, 2021
Yu Chen, Mengyao Hu, F. Deng, Ping Wang, Jing Lin, Z. Zheng, Yunzhi Liu, Lijun Dong, Xiao Lu, Zhengliang Chen, Jia Zhou, Daming Zuo   +11 more
semanticscholar   +1 more source

Mannan-binding protein, a complement activating animal lectin

Immunopharmacology, 1992
Mannan-binding protein is an animal serum lectin (i.e. a molecule with the ability to bind specifically to certain carbohydrate structures). The relevant carbohydrate ligands are found on many pathogenic microorganisms. After binding to suitable carbohydrate ligands, mannan-binding protein is found to be an activator of the classical pathway of ...
openaire   +4 more sources

Mannan‐binding lectin and its role in innate immunity

Transfusion Medicine, 2002
Summary Mannan‐binding lectin (MBL) is a plasma collectin (C‐type lectin with a collagen‐like domain) and is considered an important component of innate immunity. Circulating MBL is genetically determined for the major part, but plasma concentration is also markedly influenced by nongenetic factors.
openaire   +3 more sources

Phospholipid-binding activity of human mannan-binding lectin

Immunology Letters, 1998
Some C-type lectins possess phospholipid-binding ability, which may be of physiological importance. Human mannan-binding lectin (MBL) was found to bind specifically to solid-phase phosphatidylserine (PS), phosphatidylinositol (PI) and phosphatidylcholine (PC), but not cardiolipin (CL), in a concentration-dependent manner. This property was inhibited by
openaire   +3 more sources

Identification and characterization of two mannan-binding lectin associated proteins in lectin complement pathway of grass carp.

Developmental and Comparative Immunology, 2020
Dan-Dan Chen, Yuan-yuan Yao, Yong‐An Zhang   +2 more
semanticscholar   +1 more source

Interaction of mannan-binding lectin with IgA

Immunopharmacology, 2000
Mohamed R. Daha, Anja Roos, Ria Faber-Krol, Daniëlle J. van Gijlswijk-Janssen   +3 more
openaire   +2 more sources

Highly pathogenic coronavirus N protein aggravates inflammation by MASP-2-mediated lectin complement pathway overactivation

Signal Transduction and Targeted Therapy, 2022
Lin Zhu, Shoudeng Chen, Xiu-Wu Bian
exaly  

P1752 Mannan-binding lectin in neonates

International Journal of Antimicrobial Agents, 2007
I. Domzalska-Popadiuk, M. Cedzynski, Jerzy Szczapa, M. Turner, M. Borkowska, A. Szala, Misao Matsushita, Anna St. Swierzko, David C. Kilpatrick, S. MacDonald, J. Szemraj, A. Atkinson   +11 more
openaire   +2 more sources