Results 21 to 30 of about 89,044 (334)
The ‘involution’ of mannose-binding lectin [PDF]
Human Molecular Genetics, 2005 Mannose-binding lectin (MBL) acts as a serum opsonin in innate immune defense and induces complement activation by the lectin pathway. In humans, low levels of functional serum MBL are caused by the dominant action of three single nucleotide substitutions in exon 1 that disrupt the glycine-rich backbone structure of the protein.
Hans O. Madsen +2 more
openaire +3 more sources
Cells, 2021 Betacoronaviruses, responsible for the “Severe Acute Respiratory Syndrome” (SARS) and the “Middle East Respiratory Syndrome” (MERS), use the spikes protruding from the virion envelope to attach and subsequently infect the host cells.
Annick Barre +7 more
doaj +1 more source
Thrombosis and Haemostasis, 2020 The ongoing COVID-19 pandemic has caused significant morbidity and mortality worldwide, as well as profound effects on society. COVID-19 patients have an increased risk of thromboembolic (TE) complications, which develop despite pharmacological ...
O. Eriksson +6 more
semanticscholar +1 more source
Mannose‐binding lectin and gastric cancer [PDF]
International Journal of Cancer, 2007 Daniel L. Worthley*, Peter G. Bardy, David L. Gordon and Charles G. Mullighan Department of Gastroenterology and Hepatology, Flinders Medical Centre, South Australia, Australia Division of Hematology, Royal Adelaide Hospital and Institute of Medical and Veterinary Science, South Australia, Australia Department of Hematology–Oncology, The Queen ...
Daniel L. Worthley +4 more
openaire +4 more sources
Definitions, 2020 A recombinant protein similar or identical to human mannan-binding lectin (MBL) with opsonin activity. MBL, a soluble pattern recognition receptor (PRR) collectin in the C-type lectin superfamily, is a plasma protein that plays an important role in ...
semanticscholar +1 more source
Hepatology, EarlyView., 2022 Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog +12 more
wiley +1 more source
Structural determinants for activity and specificity of the bacterial toxin LlpA. [PDF]
PLoS Pathogens, 2013 Lectin-like bacteriotoxic proteins, identified in several plant-associated bacteria, are able to selectively kill closely related species, including several phytopathogens, such as Pseudomonas syringae and Xanthomonas species, but so far their mode of ...
Maarten G K Ghequire +5 more
doaj +1 more source
Mannose-Binding Lectin in HIV Infection [PDF]
Future Virology, 2008 Infection with HIV represents a significant global health problem, with high infection rates and high mortality worldwide. Treatment with antiretroviral therapy is inaccessible to many patients and efficacy is limited by development of resistance and side effects.
A Dzwonek, Sarah Eisen, Nigel Klein
openaire +3 more sources
Mannose-Binding Lectin and Liver Transplantation [PDF]
Gastroenterology, 2005 Daniel L. Worthley +4 more
openalex +3 more sources
High mannose-specific lectin Msl mediates key interactions of the vaginal Lactobacillus plantarum isolate CMPG5300 [PDF]
, 2016 To characterize the interaction potential of the human vaginal isolate Lactobacillus plantarum CMPG5300, its genome was mined for genes encoding lectin-like proteins.
Balzarini, Jan +10 more
core +1 more source