Results 71 to 80 of about 41,940 (203)

Proteomics analysis of serum protein profiling in pancreatic cancer patients by DIGE: up-regulation of mannose-binding lectin 2 and myosin light chain kinase 2

BMC Gastroenterology, 2010
Background Pancreatic cancer has significant morbidity and mortality worldwide. Good prognosis relies on an early diagnosis. The purpose of this study was to develop techniques for identifying cancer biomarkers in the serum of patients with pancreatic ...
Ni Xiaolin, Wu Wenchuan, Hu Jianwen, Hou Chenrui, Jin Dayong, Rong Yefei, Wang Dansong, Lou Wenhui   +7 more
doaj   +1 more source

Jasmonate Modulates Strawberry Susceptibility to Anthracnose by Activating SnRK2.1 to Regulate the WRKY50‐JAZ5 Module

Plant Biotechnology Journal, EarlyView.
ABSTRACT Colletotrichum spp., hemibiotrophic fungal pathogens, threaten global strawberry production. Jasmonate (JA) regulates plant‐Colletotrichum interactions, but its mechanisms remain unclear. Here we demonstrate that both exogenous methyl jasmonate (MeJA) treatment and elevated endogenous MeJA levels increase strawberry susceptibility to ...
Chuang Liu, Zhen Liu, Xia Li, Yating Chen, Ronghui Sun, Peijie Li, Qianqian Feng, Yuanhua Wang, Jie Ren, Qian Li, Bingbing Li   +10 more
wiley   +1 more source

Mannose Binding Lectin (MBL) and Its Clinical Significance

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2015
BACKGROUND AND OBJECTIVE: Mannose Binding Lectin (MBL) is a key molecule in innate immunity, this acute phase protein, synthesized in the liver, binds to various microorganisms and damaged cells and destroys them by opsonization of aggressive agents and ...
M Asgharzadeh, H Samadi Kafil, M Pourastadi   +2 more
doaj  

Impact of bacterial vaginosis, as assessed by nugent criteria and hormonal status on glycosidases and lectin binding in cervicovaginal lavage samples.

PLoS ONE, 2015
The objective of this study was to evaluate the impact of hormonal status and bacterial vaginosis (BV) on the glycosidases present and glycosylation changes as assessed by lectin binding to cervicovaginal lavage constituents. Frozen cervicovaginal lavage
Bernard J Moncla, Catherine A Chappell, Lara K Mahal, Brian M Debo, Leslie A Meyn, Sharon L Hillier   +5 more
doaj   +1 more source

Transcript correlation analysis for the identification of novel plant genes involved in iron metabolism and beyond: what next?

Plant Biology, EarlyView.
Transcript correlation analysis allowed the identification of several key nodes in the complex regulatory network of plant iron metabolism. Abstract Arabidopsis thaliana was the first plant genome to be fully sequenced, almost a quarter of a century ago, thanks to The Arabidopsis Genome Initiative, with contributions from scientists worldwide.
I. Murgia, P. Morandini
wiley   +1 more source

Glycan microarray analysis of the carbohydrate-recognition specificity of native and recombinant forms of the lectin ArtinM

Data in Brief, 2015
This article contains data related to the researc.h article entitled “Yeast-derived ArtinM shares structure, carbohydrate recognition, and biological effects with native ArtinM” by Cecílio et al. (2015) [1].
Y. Liu, N.T. Cecílio, F.C. Carvalho, M.C. Roque-Barreira, T. Feizi   +4 more
doaj   +1 more source

Histiocytes: Multifaceted Regulators of Health and Disease

Veterinary Clinical Pathology, EarlyView.
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley   +1 more source

Bacterial surface display of human lectins in Escherichia coli

Microbial Biotechnology
Lectin‐glycan interactions sustain fundamental biological processes involved in development and disease. Owing to their unique sugar‐binding properties, lectins have great potential in glycobiology and biomedicine.
Alba Vázquez‐Arias, Lorena Vázquez‐Iglesias, Ignacio Pérez‐Juste, Jorge Pérez‐Juste, Isabel Pastoriza‐Santos, Gustavo Bodelon   +5 more
doaj   +1 more source

Recombinant Mannose-binding Lectin Protein and Anti-Mannose-binding Lectin Polyclonal Antibody Production

Journal of Life Science, 2009
The innate immune system is important for the first line of host defence against infectious agents, which have penetrated the mechanical barriers. Mannose-binding lectin (MBL or mannan-binding protein, MBP) is a serum protein that is synthesized in the liver as a part of the acute phase response. MBL binds to carbohydrate structures presented by a wide
openaire   +2 more sources

Autosomal Dominant Erythrocytosis Caused by Non‐Renal Erythropoietin (EPO) Due to EPO c.‐136 G>A Germline Mutation

American Journal of Hematology, Volume 101, Issue 4, Page 784-793, April 2026.
A novel erythropoietin (EPO) promoter mutation (c.‐136 G>A) causes autosomal dominant erythrocytosis via non‐renal expression of EPO. ABSTRACT We previously reported a five‐generation kindred with autosomal dominant erythrocytosis associated with a novel germline promoter variant in the erythropoietin (EPO) gene (EPO c.‐136 G>A).
Lucie Lanikova, Dusan Hrckulak, Veronika Zimolova, Felipe R. Lorenzo, Jihyun Song, Katerina Vecerkova, Olga Babosova, Linda Berkova, Vladimir Korinek, Steve Elliott, Josef T. Prchal   +10 more
wiley   +1 more source