Results 51 to 60 of about 2,415,950 (382)
Carbohydrate recognition by the mannose-6-phosphate receptors [PDF]
Current Opinion in Structural Biology, 2009 The two P-type lectins, the 46kDa cation-dependent mannose-6-phosphate (Man-6-P) receptor (CD-MPR), and the 300kDa cation-independent Man-6-P receptor (CI-MPR), are the founding members of the growing family of mannose-6-phosphate receptor homology (MRH) proteins.
Linda J. Olson +2 more
openaire +3 more sources
A truncated lipoglycan from mycobacteria with altered immunological properties [PDF]
, 2010 Maintenance of cell-wall integrity in Mycobacterium tuberculosis is essential and is the target of several antitubercular drugs. For example, ethambutol targets arabinogalactan and lipoarabinomannan (LAM) biosynthesis through the inhibition of several ...
Alderwick, Luke J. +9 more
core +2 more sources
Proceedings of the National Academy of Sciences of the United States of America, 2022 Significance PD-L1 is well known as an immune checkpoint molecule, which suppresses immune surveillance through binding to its receptor PD-1. Intracellular PD-L1 can also protect messenger RNAs of several DNA damage repair–related genes from degradation ...
Ruonan Zhang +12 more
semanticscholar +1 more source
Mannoside-Modified Branched Gold Nanoparticles for Photothermal Therapy to MDA-MB-231 Cells
Molecules, 2020 Recently, gold nanoparticles (Au NPs) have been used to study the treatment of malignant tumors due to their higher biocompatibility and lesser toxicity.
Han-Chen Lin +5 more
doaj +1 more source
Frontiers in Drug Delivery, 2023 The targeting and conversion of the immunosuppressive (M2) tumor-associated macrophages (TAMs) to an immunostimulatory (M1) phenotype can induce tumor regression in advanced melanoma.
Akpedje S. Dossou +5 more
doaj +1 more source
Biosynthesis and expression of zona pellucida glycoproteins in mammals [PDF]
, 2001 The zona pellucida (ZP) is an extracellular matrix surrounding the oocyte and the early embryo that exerts several important functions during fertilization and early embryonic development.
Kölle, S. +2 more
core +1 more source
Glycoform Modification of Secreted Recombinant Glycoproteins through Kifunensine Addition during Transient Vacuum Agroinfiltration. [PDF]
, 2018 Kifunensine, a potent and selective inhibitor of class I α-mannosidases, prevents α-mannosidases I from trimming mannose residues on glycoproteins, thus resulting in oligomannose-type glycans.
Kailemia, Muchena J +5 more
core +3 more sources
Experimental Trichinellosis in rats: Peritoneal macrophage activity [PDF]
Archives of Biological Sciences, 2010 The influence of Trichinella spiralis infection on macrophage activity in rats during the first 28 days of infection was examined by measuring the production of NO and IL-6, as well as the expression of mannose receptor on the surface of peritoneal ...
Gruden-Movsesijan Alisa +1 more
doaj +1 more source
Glycoprotein Targeted CAR-NK Cells for the Treatment of SARS-CoV-2 Infection
Frontiers in Immunology, 2021 H84T-Banana Lectin (BanLec) CAR-NK cells bind high mannose glycosites that decorate the SARS-CoV-2 envelope, thereby decreasing cellular infection in a model of SARS-CoV-2. H84T-BanLec CAR-NK cells are innate effector cells, activated by virus.
Ilias Christodoulou +11 more
doaj +1 more source
PLoS ONE, 2016 Dengue fever is a mosquito-borne viral pandemic disease that is widespread in the tropical and subtropical areas. Dengue virus uses human mannose-binding receptor (MR) and DC-SIGN on macrophages as primary receptors, and CLEC5A as signaling receptor to ...
Yen-Lung Lo +5 more
semanticscholar +1 more source