Results 11 to 20 of about 1,043,830 (367)

Mos stimulates MAP kinase in Xenopus oocytes and activates a MAP kinase kinase in vitro. [PDF]

Molecular and Cellular Biology, 1993
Several protein kinases, including Mos, maturation-promoting factor (MPF), mitogen-activated protein (MAP) kinase, and MAP kinase kinase (MAPKK), are activated when Xenopus oocytes enter meiosis. De novo synthesis of the Mos protein is required for progesterone-induced meiotic maturation.
Jonathan A. Cooper, G F Vande Woude, N Yew, James Posada, Natalie G. Ahn   +4 more
semanticscholar   +6 more sources

Different roles for non-receptor tyrosine kinases in arachidonate release induced by zymosan and Staphylococcus aureus in macrophages [PDF]

Journal of Inflammation, 2006
BACKGROUND: Yeast and bacteria elicit arachidonate release in macrophages, leading to the formation of leukotrienes and prostaglandins, important mediators of inflammation.
Olsson, Sandra, Sundler, Roger
core   +5 more sources

Molecular structure of a protein-tyrosine/threonine kinase activating p42 mitogen-activated protein (MAP) kinase: MAP kinase kinase. [PDF]

Proceedings of the National Academy of Sciences of the United States of America, 1993
MAP kinases p42mapk and p44mapk participate in a protein kinase cascade(s) important for signaling in many cell types and contexts. Both MAP kinases are activated in vitro by MAP kinase kinase, a protein-tyrosine and threonine kinase. A MAP kinase kinase
Jianguo Wu, Jeffrey K. Harrison, L A Vincent, Clare M.M. Haystead, Timothy Haystead, H Michel, Donald F. Hunt, Kevin R. Lynch, T W Sturgill   +8 more
openalex   +2 more sources

Computational Prediction and Experimental Verification of New MAP Kinase Docking Sites and Substrates Including Gli Transcription Factors [PDF]

PLoS Computational Biology, 2010
In order to fully understand protein kinase networks, new methods are needed to identify regulators and substrates of kinases, especially for weakly expressed proteins.
A Bateman, A Bruna, A Krogh, A Moumen, A Ruiz i Altaba, AB Kusari, AD Sharrocks, AJ Bardwell, AJ Bardwell, AJ Bardwell, AM Moses, B Carpenter, B Kobe, B Stecca, B Stecca, BD Manning, BE Turk, BJ Yoon, C Ducret, C Wiltshire, CW Chow, D Barsyte-Lovejoy, D Jacobs, DA Fantz, David T. Ho, DL Sheridan, DM Gwinn, DS Schullery, DT Ho, DT Ho, EG Huntzicker, EJ Goldsmith, Elizabeth A. Gordon, G Manning, G Temple, GE Crooks, GL Johnson, H Enslen, H Habelhah, H Habelhah, H Sasaki, H Schnidar, I Van Seuningen, J Avruch, J Gerhart, J Jiang, J Lin, J Mok, J Ptacek, J Yasuda, JA Ubersax, JC Obenauer, Jeffrey S. Rogers, JM Ruppert, JV Olsen, K Awano, K Bomsztyk, K Saigo, L Bardwell, L Bardwell, L Chang, Lan Huang, Lee Bardwell, LG Biesecker, LM Iakoucheva, M Dickens, M Dunaeva, M Ito, M Kashiwaba, M Kasper, M Kasper, M Lauth, M Notari, M Seto, MA Bogoyevitch, MA Bogoyevitch, MC Lawrence, MP Fogarty, N Kelkar, N Kelkar, N Kessaris, NA Riobo, O Nolan-Stevaux, O Yazgan, ON Denisenko, P Baldi, P Baldi, P Baldi, P Baldi, Pierre Baldi, PM Holland, R Akella, R Linding, RB Pearson, RM Biondi, RM Kaake, Robyn M. Kaake, Ryan W. Benz, S Mukherjee, S Yoon, SA Johnson, SB Needleman, SH Yang, SR Eddy, SR Eddy, T Kallunki, T Osterlund, T Riley, T Tanoue, TA Rosenquist, Thomas C. Whisenant, Thomas Lengauer, TS Lewis, U Reineke, V Aguirre, WE Miller, Y Yoo, YV Budovskaya, Z Ji, Z Songyang, Z Zhang   +120 more
core   +7 more sources

Staphylococcal PknB as the First Prokaryotic Representative of the Proline-Directed Kinases [PDF]

PLoS ONE, 2010
In eukaryotic cell types, virtually all cellular processes are under control of proline-directed kinases and especially MAP kinases. Serine/threonine kinases in general were originally considered as a eukaryote-specific enzyme family.
Becher, Doerte, Diks, Sander H., Donat, Stefanie, Dreisbach, Annette, Gronau, Katrin, Kouwen, Thijs R. H. M., Miller, Malgorzata, Ohlsen, Knut, Peppelenbosch, Maikel P., Rakette, Sonja, Reilman, Ewoud, Stehle, Thilo, van Dijl, Jan Maarten   +12 more
core   +5 more sources

MAP-ping genomic organization and organ-specific expression profiles of poplar MAP kinases and MAP kinase kinases [PDF]

BMC Genomics, 2006
Abstract Background As in other eukaryotes, plant mitogen-activated protein kinase (MAPK) cascades are composed of three classes of hierarchically organized protein kinases, namely MAPKKKs, MAPKKs, and MAPKs. These modules rapidly amplify and transduce extracellular signals into various appropriate intracellular ...
Brian E. Ellis, Marie-Claude Nicole, Nathalie Beaudoin, Louis-Philippe Hamel, Louis-Philippe Hamel, Marie-Josée Morency, Armand Séguin   +6 more
openaire   +5 more sources

Regulation of Nuclear Envelope Assembly/Disassembly by MAP Kinase [PDF]

, 1996
Mouse eggs arrested in metaphase II display high levels of cdc2/cyclin B1 and MAP protein kinase activities. Following fertilization there is a time-dependent decrease in the activity of each of these protein kinases.
Kopf, Gregory S., Moos, Jiri, Schultz, Richard M., Xu, Zhe   +3 more
core   +2 more sources

Regulation and function of TPL-2, an IκB kinase-regulated MAP kinase kinase kinase [PDF]

Cell Research, 2010
The IκB kinase (IKK) complex plays a well-documented role in innate and adaptive immunity. This function has been widely attributed to its role as the central activator of the NF-κB family of transcription factors. However, another important consequence of IKK activation is the regulation of TPL-2, a MEK kinase that is required for activation of ERK-1 ...
Thorsten Gantke, Srividya Sriskantharajah, Steven C. Ley   +2 more
openaire   +4 more sources

MAP Kinase Pathways [PDF]

Cold Spring Harbor Perspectives in Biology, 2012
MAP kinases are activated within protein kinase cascades that regulate cell proliferation, differentiation, and death. In mammals, MAP kinases are grouped into three families: ERKs, JNKs, and p38/SAPKs.
D. Morrison
openaire   +3 more sources

Redox Regulation, Rather than Stress-Induced Phosphorylation, of a Hog1 Mitogen-Activated Protein Kinase Modulates Its Nitrosative-Stress-Specific Outputs [PDF]

mBio, 2018
Data availability. The RNA sequencing dataset is available at EBI (www.ebi.ac.uk/arrayexpress/) under accession number E-MTAB-5990. Other data that support the findings of this study are available from the corresponding author upon reasonable request ...
Alison M. Day, Alistair J. P. Brown, Anna T. Tillmann, Carmen Herrero-de-Dios, David Stead, Janet Quinn, Michael Lorenz, Paula S. Salgado, Stavroula L. Kastora   +8 more
core   +4 more sources