Kinome profiling reveals pathogenic variant specific protein signalling networks in MEN2 children with Medullary Thyroid Cancer. [PDF]
Rix B+12 more
europepmc +1 more source
The Regulation of Trace Metal Elements in Cancer Ferroptosis
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang+5 more
wiley +1 more source
The "DDVF" motif used by viral and bacterial proteins to hijack RSK kinases mimics a short linear motif (SLiM) found in proteins related to the RAS-ERK MAP kinase pathway. [PDF]
Veinstein M+4 more
europepmc +1 more source
Mesenchymal stem cell‐derived nanoghosts (MSC‐NGs) mimic naturally secreted extracellular vesicles (MSC‐EVs) in structure and physicochemical properties but can be synthesized at more translatable yields. As osteogenic agents, MSC‐NGs demonstrate superior outcomes compared to MSC‐EVs.
Antoine Karoichan+4 more
wiley +1 more source
Repurposing of the Syk inhibitor fostamatinib using a machine learning algorithm. [PDF]
Choi Y+8 more
europepmc +1 more source
Effect of human papillomavirus type 16 oncogenes on MAP kinase activity
Zhengxian Gu, Greg Matlashewski
openalex +1 more source
The Mitogen-activated Protein (MAP) Kinase p38 and Its Upstream Activator MAP Kinase Kinase 6 Are Involved in the Activation of Signal Transducer and Activator of Transcription by Hyperosmolarity [PDF]
Johannes G. Bode+6 more
openalex +1 more source
Activation and signaling of the p38 MAP kinase pathway
Tyler Zarubin, Jiahuai Han
semanticscholar +1 more source
This review covers the recent advances in the synthesis and properties of stable radical polymers (SRPs) and presents their applications in electronics, magnetics, optoelectronics, and biomedicines. The review concludes with a discussion of the challenges in radical chemistry and functionalization, while shedding light on the groundbreaking potential ...
Yufeng Xiong+11 more
wiley +1 more source
Bibliometric analysis of hepatocellular carcinoma and tyrosine kinase inhibitors. [PDF]
Wu W, Mao H, Song J, Yang F.
europepmc +1 more source