Time courses of changes in phospho- and total- MAP kinases in the cochlea after intense noise exposure. [PDF]
PLoS ONE, 2013 Mitogen-activated protein kinases (MAP kinases) are intracellular signaling kinases activated by phosphorylation in response to a variety of extracellular stimuli.
Yukihide Maeda +4 more
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MAP kinases differentially bind and phosphorylate NOS3 via two unique NOS3 sites
FEBS Open Bio, 2022 Nitric oxide synthase 3 (NOS3) is a major vasoprotective enzyme that catalyzes the conversion of l‐arginine to nitric oxide (NO) in response to a significant number of signaling pathways.
Xzaviar K. V. Solone +9 more
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The NDR kinase scaffold HYM1/MO25 is essential for MAK2 map kinase signaling in Neurospora crassa. [PDF]
PLoS Genetics, 2012 Cell communication is essential for eukaryotic development, but our knowledge of molecules and mechanisms required for intercellular communication is fragmentary.
Anne Dettmann +5 more
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A subcellular map of the human kinome
eLife, 2021 The human kinome comprises 538 kinases playing essential functions by catalyzing protein phosphorylation. Annotation of subcellular distribution of the kinome greatly facilitates investigation of normal and disease mechanisms.
Haitao Zhang +21 more
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Mitogen-activated protein kinases are associated with the regulation of physiological traits and virulence in Fusarium oxysporum f. sp. cubense. [PDF]
PLoS ONE, 2015 Fusarium oxysporum f. sp. cubense (FOC) is an important soil-borne fungal pathogen causing devastating vascular wilt disease of banana plants and has become a great concern threatening banana production worldwide.
Zhaojian Ding +6 more
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Nature Communications, 2020 SnRK2 protein kinases play key roles in signaling during plant responses to abiotic stress. Here Soma et al. report three Arabidopsis Raf-like MAP kinase kinase kinases phosphorylate and activate a subclass of SnRK2s that rapidly respond to osmotic ...
Fumiyuki Soma +4 more
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Plant and Cell Physiology, 2015 We isolated an Arabidopsis ABA-insensitive mutant, ais143, by activation tagging screen. T-DNA was found to be located in the coding region of a putative mitogen-activated protein (MAP) kinase kinase kinase (MAP3K) gene, Raf10, thereby abolishing its ...
Sun-ji Lee +3 more
semanticscholar +1 more source
MAP Kinase Regulation of the
mSphere, 2019 We investigated the relationships of the Cek1 and Cek2 mitogen-activated protein (MAP) kinases and the putative MAP kinase phosphatase Cpp1 in the mating process of Candida albicans.
Golnaz Rastghalam +5 more
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The germinal center kinase GCK-1 is a negative regulator of MAP kinase activation and apoptosis in the C. elegans germline. [PDF]
PLoS ONE, 2009 The germinal center kinases (GCK) constitute a large, highly conserved family of proteins that has been implicated in a wide variety of cellular processes including cell growth and proliferation, polarity, migration, and stress responses.
Katherine R Schouest +5 more
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MAP kinase activation by mu opioid receptor involves phosphatidylinositol 3-kinase but not the cAMP/PKA pathway [PDF]
, 1999 The involvement of protein kinases was studied in mu opioid receptor activation of mitogen-activated protein (MAP) kinase using cells transfected with the receptor clone.
Ai, Wandong, Gong, Jianhua, Yu, Lei
core +1 more source