Results 251 to 260 of about 436,308 (305)

Pedunculoside targets P2X7R to protect against myocarditis by regulating the NLRP3/PIP2/MAPK signaling pathway. [PDF]

Front Pharmacol
Zhuo Y, He J, Wang QQ, Xiao Y, Xie X, Liu L, Yang S, Li J, Yuan R, Gao H.   +9 more
europepmc   +1 more source

Liver Kinase B1 in CD11c+ Cells Inhibits Fibrosis in Chronic Pancreatitis via the Oncostatin M Signaling

Advanced Science, EarlyView.
This study demonstrates significantly reduced Lkb1 expression in CD11c+ cells in chronic pancreatitis (CP) patients and animal models. Lkb1 deletion enhances CD11c+CD206+ macrophage infiltration and reprograms pancreatic stellate cells (PSCs) via OSM signaling.
Wenqing Zhang, Shan Guo, Yu Zhang, He Ren, Ke Lei, Chenyang Zhao, Qian Yu, Hongqing Luo, Yujing Xiao, Xiaoming Feng, Xiaoyu Li   +10 more
wiley   +1 more source

The Negative Role of Ankyrin-Repeat and SOCS-Box Protein 9 in PAR1 Expression and the MAPK Signaling Pathway in Bovine Granulosa Cells. [PDF]

Biology (Basel)
Naranjo Gonzalez D, Ndiaye K.
europepmc   +1 more source

Sono‐Mechanogenetics: Linking Ultrasound Physics With Cellular Mechanobiology

Advanced Science, EarlyView.
Sono‐mechanogenetics links ultrasound physics with cellular mechanotransduction to enable noninvasive control of engineered biological systems. Acoustic forces generate distinct deformation modes that activate intracellular signaling pathways, which can be coupled to synthetic gene circuits to regulate diverse cellular functions, including gene ...
Yunjia Qu, Fan Wei, Chi Woo Yoon, Qifa Zhou, Yingxiao Wang   +4 more
wiley   +1 more source

Selenium‐Based Nanoplatforms: An Emerging Theranostic Paradigm for Gynecological Cancers

Advanced Science, EarlyView.
This reivew summarizes Selenium as a multifunctional anticancer regulator in gynecological cancers. It reduces tumor risk, enhances therapeutic efficacy, and reduces treatment toxicity. Selenium also overcomes chemoraditherapy resistance, improving overall treatment outcomes. ABSTRACT Gynecological cancers present significant therapeutic challenges due
Hejing Liu, Yujia Zhou, Zihan Zhang, Rong Ma, Luyi Ruan, Liqing Miao, Boxin Zhang, Huihui Ji, Tianfeng Chen, Xueqiong Zhu   +9 more
wiley   +1 more source

The Role of the MAPK Signaling Pathway in Cardiovascular Disease: Pathophysiological Mechanisms and Clinical Therapy. [PDF]

Int J Mol Sci
Wang X, Liu R, Liu D.
europepmc   +1 more source

Therapeutic effects of three-strain probiotic combination on slow transit constipation: mechanistic insights into MAPK signaling pathway and gut microbiota restoration. [PDF]

Front Pharmacol
Liu L, Li P, Chen Y, Yang G, Cheng Y, Liu S, Zhang X, Wu Y, Liu Q, Zhao P, Fang W, Ren Y, Hu L, Liu Y, Li K, Chen Z, Ke X, Li Q, Shen A.   +18 more
europepmc   +1 more source

The exosomal miR-26b-3p derived from Crohn's disease-associated mesenteric adipose tissue induces M1 macrophage polarization and exacerbates ileocolonic anastomosis inflammation via the p38-MAPK signaling pathway. [PDF]

Front Immunol
Wu E, Qian W, Zhang X, Gu L, Guo Z, Yu Z, Li Y, Zhu W.   +7 more
europepmc   +1 more source

MAPK signaling pathway in development of Alzheimer’s disease

11-ая Международная конференция по биоинформатике регуляции и структуры геномов и системной биологии, 2018
openaire   +1 more source

[Retracted] Overexpression of TGF-β enhances the migration and invasive ability of ectopic endometrial cells via ERK/MAPK signaling pathway. [PDF]

Exp Ther Med
Liu Z, Yi L, Du M, Gong G, Zhu Y.
europepmc   +1 more source