Results 231 to 240 of about 288,292 (262)
Some of the next articles are maybe not open access.
The MAPK Signal Pathway Research and New Drug Discovery
2009 Ninth IEEE International Conference on Bioinformatics and BioEngineering, 2009MAPK cell signal transduction pathways determine the survival of the cells. If one can control this pathways, and then they will prohibit the proliferation of the cancer cells. Furthermore, they will heal the cancer smoothly. In order to attain this goal, we use lots of drugs to interact with MEK1 in MAPK, by using computer aided drug design to analyze
Po-Yuan Chen +4 more
openaire +1 more source
[MAPK signaling pathway and erectile dysfunction].
Zhonghua nan ke xue = National journal of andrology, 2018The MAPK signaling pathway plays a key role in the differentiation, proliferation and apoptosis of cells, and its family members mainly include extracellular signal-regulated kinase (ERK), stress-activated protein kinase (JNK), and p38 mitogen-activated protein kinase (p38MAPK). Recent studies have shown that the ERK, JNK and p38MAPK signaling pathways
Si-Xiang, Chen +2 more
openaire +1 more source
The Role of MAPK/p38 Signalling Pathway in Cancer
Journal of Clinical and Medical Research, 2023Cancer is one of the fatal diseases globally. It is unfortunate that despite many years of devoted studies towards finding a better therapeutic approach, the scourge of the disease has continued to rise with attendant mortalities. Many studies have been devoted to finding constructive clues to the pathways that are implicated in the onset and ...
openaire +1 more source
Regulation of cross-talk in yeast MAPK signaling pathways
Current Opinion in Microbiology, 2010MAP kinase (MAPK) modules are conserved three-kinase cascades that serve central roles in intracellular signal transduction in eukaryotic cells. MAPK pathways of different inputs and outputs use overlapping sets of signaling components. In yeast, for example, three MAPK pathways (pheromone response, filamentous growth response, and osmostress ...
openaire +2 more sources
MAPK signaling pathway and endometriosis: what is the link?
Archives of Gynecology and Obstetrics, 2012Endometriosis is defined as the presence of endometrial tissue outside the uterus, predominantly on the ovary and pelvic peritoneum [1]. It occurs in approximately 10 % of women of reproductive age and, although it is a benign disease, it causes infertility and pelvic pain, compromising the quality of life [1].
Raffaella, Mormile, Giorgio, Vittori
openaire +2 more sources
Wound signaling-coordination of the octadecanoid and MAPK pathways
Plant Physiology and Biochemistry, 2003Abstract Plants have developed integrated signaling networks that play a pivotal role in mediating the perception of and response to environmental factors, including wounding, a common stress. Wound signaling is known to involve at least two major signaling pathways—the octadecanoid and the MAPK pathways.
Randeep Rakwal, Ganesh Kumar Agrawal
openaire +1 more source
TAB1 Links MAPK Signaling to the p53 Pathway
Cancer Discovery, 2013Abstract TAB1 interacts with MDM2 and regulates p53-mediated cell death in response to cisplatin.
openaire +1 more source
Regulation of MAPK/JNK signaling pathway and TGF-beta signaling pathway by axin
2014Axin was originally identified from the characterization of the Fused locus, the disruption of which leads to duplication of axis and embryonic lethality. Axin is a multidomain protein that interacts with multiple proteins and functions as a negative regulator of Wnt signaling by downregulating the β-catenin levels. It also plays an important role in a
openaire +2 more sources
Non-Coding RNA Related to MAPK Signaling Pathway in Liver Cancer
International Journal of Molecular Sciences, 2022Liling Tang +2 more
exaly
MAPK Signaling Pathway in Oral Squamous Cell Carcinoma: Biological Function and Targeted Therapy
Cancers, 2022Zhangui Tang, Juan Chen, Yuxi Cheng
exaly