Results 281 to 290 of about 436,308 (305)
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TAB1 Links MAPK Signaling to the p53 Pathway
Cancer Discovery, 2013Abstract TAB1 interacts with MDM2 and regulates p53-mediated cell death in response to cisplatin.
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Regulation of MAPK/JNK signaling pathway and TGF-beta signaling pathway by axin
2014Axin was originally identified from the characterization of the Fused locus, the disruption of which leads to duplication of axis and embryonic lethality. Axin is a multidomain protein that interacts with multiple proteins and functions as a negative regulator of Wnt signaling by downregulating the β-catenin levels. It also plays an important role in a
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Targeting the RAS/RAF/MAPK pathway for cancer therapy: from mechanism to clinical studies
Signal Transduction and Targeted Therapy, 2023Md Entaz Bahar, Deok-Ryong Kim
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MAPK Signaling Pathway in Oral Squamous Cell Carcinoma: Biological Function and Targeted Therapy
Cancers, 2022雨熹 成, Juan Chen, Zhangui Tang
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Structural keys unlock RAS–MAPK cellular signalling pathway
Nature, 2022Hugo Lavoie, Marc Therrien
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Targeting the MAPK Pathway in KRAS-Driven Tumors
Cancer Cell, 2020Matthias Drosten, Mariano Barbacid
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