Results 61 to 70 of about 36,270 (266)

Automation of an integrated micro‐scale platform for monoclonal antibody process development by incorporation of a depth filter mimic

Biotechnology Progress, EarlyView.
Integrating non‐chromatographic operations, such as low pH viral inactivation and a depth filtration mimic, into an automated micro‐scale platform enhances productivity while reducing resource and time requirements. By facilitating rapid, data‐rich experimentation, the platform offers a powerful and efficient tool for assessing and optimizing ...
Paras Sharma, Petra Sebastian, Lars Robbel, Michael Schmitt, Daniel G. Bracewell   +4 more
wiley   +1 more source

Identification of CCZ1 as an essential lysosomal trafficking regulator in Marburg and Ebola virus infections

Nature Communications, 2023
Marburg and Ebola filoviruses are two of the deadliest infectious agents and several outbreaks have occurred in the last decades. Although several receptors and co-receptors have been reported for Ebola virus, key host factors remain to be elucidated. In
Vanessa Monteil, Hyesoo Kwon, Lijo John, Cristiano Salata, Gustav Jonsson, Sabine U. Vorrink, Sofia Appelberg, Sonia Youhanna, Matheus Dyczynski, Alexandra Leopoldi, Nicole Leeb, Jennifer Volz, Astrid Hagelkruys, Max J. Kellner, Stéphanie Devignot, Georg Michlits, Michelle Foong-Sobis, Friedemann Weber, Volker M. Lauschke, Moritz Horn, Heinz Feldmann, Ulrich Elling, Josef M. Penninger, Ali Mirazimi   +23 more
doaj   +1 more source

Infection Risk From Humans and Animals in the Anatomy Laboratory: A Scoping Review

Clinical Anatomy, EarlyView.
ABSTRACT Whole‐body dissection is a cornerstone of anatomy education. During and following the COVID‐19 pandemic, exposure to infectious agents and other risks of dissection were highlighted. To identify potential risks, one must have the data outlining these risks in specific situations.
Margaret A. McNulty, Elizabeth R. Agosto
wiley   +1 more source

PPARγ and LXR Signaling Inhibit Dendritic Cell-Mediated HIV-1 Capture and trans-Infection [PDF]

, 2010
Dendritic cells (DCs) contribute to human immunodeficiency virus type 1 (HIV-1) transmission and dissemination by capturing and transporting infectious virus from the mucosa to draining lymph nodes, and transferring these virus particles to CD4+ T cells ...
Blay Puryear, Wendy, Gummuluru, Suryaram, Hanley, Timothy M., Viglianti, Gregory A.   +3 more
core   +5 more sources

Second Attempt at America First: Donald Trump and the Survival of International Organizations

Global Policy, EarlyView.
ABSTRACT The second Trump administration poses an existential challenge to many international organizations (IOs), putting them at risk of no longer being able to perform their core functions. Compared to the first term, the scope of America First is much wider and the speed much faster.
Hylke Dijkstra
wiley   +1 more source

Health services for survivors of gender-based violence in northern Uganda: a qualitative study.

, 2008
The 20-year war in northern Uganda has resulted in up to 1.7 million people being internally displaced, and impoverishment and vulnerability to violence amongst the civilian population.
Borchert, Matthias, Henttonen, Mirkka, Kaducu, Felix, Roberts, Bayard, Watts, Charlotte   +4 more
core   +1 more source

Screening donors for xenotransplantation: The potential for xenozoonoses [PDF]

, 1994
Xenotransplantation is a potential solution to the current donor shortage for solid organ transplantation. The transmission of infectious agents from donor organs or bone marrow to the recipient is a well-recognized phenomenon following ...
Kahleen, B, Kalter, S, McMichael, JP, Michaels, MG, Peters, RL, Simmons, RL, Starzl, TE   +6 more
core   +1 more source

Forty-Five Years of Marburg Virus Research

Viruses, 2012
In 1967, the first reported filovirus hemorrhagic fever outbreak took place in Germany and the former Yugoslavia. The causative agent that was identified during this outbreak, Marburg virus, is one of the most deadly human pathogens.
Kristina Brauburger, Adam J. Hume, Judith Olejnik, Elke Mühlberger   +3 more
doaj   +1 more source

Maternal, childhood and adolescent influences on Leydig cell functional capacity and circulating INSL3 concentration in young adults: Importance of childhood infections and body mass index

Andrology, EarlyView.
Abstract Background The constitutive Leydig cell hormone insulin‐like peptide 3 (INSL3) is considered a good estimate of the adult Leydig cell functional capacity and appears to remain relatively consistent throughout adult male life, only gradually declining into old age.
Richard Ivell, Bilal Tulumcu, Waleed Alhujaili, Ravinder Anand‐Ivell   +3 more
wiley   +1 more source

Viewpoint: filovirus haemorrhagic fever outbreaks: much ado about nothing? [PDF]

, 2000
The recent outbreak of Marburg haemorrhagic fever in the Democratic Republic of Congo has put the filovirus threat back on the international health agenda.
Boelaert, M, Borchert, M, Colebunders, R, Muyembe-Tamfum, J J, Pirard, P, Sleurs, H, van der Groen, G, Van der Stuyft, P   +7 more
core   +3 more sources