Results 81 to 90 of about 1,701,603 (284)

An introduction to the Marburg virus vaccine consortium, MARVAC

PLoS Pathogens, 2022
The emergence of Marburg virus (MARV) in Guinea and Ghana triggered the assembly of the MARV vaccine “MARVAC” consortium representing leaders in the field of vaccine research and development aiming to facilitate a rapid response to this infectious ...
R. Cross, I. Longini, S. Becker, K. Bok, David Boucher, M. Carroll, Janet Diaz, W. Dowling, R. Draghia‐Akli, J. T. Duworko, J. Dye, M. Egan, P. Fast, Amy Finan, Courtney L. Finch, T. Fleming, J. Fusco, T. Geisbert, Anthony Griffiths, S. Günther, L. Hensley, A. Honko, Ruth Hunegnaw, J. Jakubik, J. Ledgerwood, K. Luhn, Demetrius Matassov, J. Meshulam, E. Nelson, C. Parks, R. Rustomjee, D. Safronetz, L. Schwartz, Dean Smith, Paul Smock, Ydrissa Sow, C. Spiropoulou, N. Sullivan, Kelly L. Warfield, Daniel Wolfe, Courtney Woolsey, R. Zahn, A. Henao-Restrepo, C. Muñoz-Fontela, A. Marzi   +44 more
semanticscholar   +1 more source

A highly attenuated Vesiculovax vaccine rapidly protects nonhuman primates against lethal Marburg virus challenge

bioRxiv, 2022
Background Marburg virus (MARV), an Ebola-like virus, remains an eminent threat to public health as demonstrated by its high associated mortality rate (23-90%) and recent emergence in West Africa for the first time.
Courtney Woolsey, R. Cross, K. Agans, V. Borisevich, D. Deer, J. Geisbert, Cheryl S. Gerardi, Theresa Latham, Karla A. Fenton, M. Egan, J. Eldridge, T. Geisbert, Demetrius Matassov   +12 more
semanticscholar   +1 more source

Treatment of Marburg and Ebola hemorrhagic fevers: A strategy for testing new drugs and vaccines under outbreak conditions. [PDF]

, 2008
The filoviruses, Marburg and Ebola, have the dubious distinction of being associated with some of the highest case-fatality rates of any known infectious disease-approaching 90% in many outbreaks.
A.G. Sprecher, Anon., Baize, Basler, Bausch, Bausch, Bausch, Bausch, Bausch, Bausch, Bausch, Bausch, Benjamin Jeffs, Bernard, Borchert, Bosio, Bosio, Boumandouki, Bray, Bray, Bray, Bray, Brummel-Ziedins, Bukreyev, Bwaka, CDC and WHO, Colebunders, Daddario-DiCaprio, Daniel G. Bausch, Dowell, Egbring, Emond, Enterlein, Feldmann, Formenty, Fourrier, Gear, Geisbert, Geisbert, Geisbert, Geisbert, Geisbert, Geisbert, Geisbert, Geisbert, Gibbs, Gupta, Hensley, Hensley, Hensley, Hewlett, Hewlett, Hoenen, Hotchkiss, Huggins, Jahrling, Jahrling, Jahrling, Jeffs, Johnson, Jones, Jones, Khan, Ksiazek, Kudoyarova-Zubavichene, Larkin, Leroy, Leroy, Mahanty, Mahanty, Martin, Martini, Martini, Monath, Mupapa, Mupapa, Nikiforov, Oswald, Parrino, Pattyn, Paul Boumandouki, Peters, Peterson, Peterson, Pourrut, Reid, Rivers, Roberts, Rollin, Sanchez, Schnittler, Schuler, Smith, Spurgers, Stille, Sullivan, Sullivan, Swanepoel, Takada, Todorovitch, Towner, Warfield, Warfield, Warfield, Wilson, Zaki   +105 more
core   +2 more sources

Obtaining Recombinant Antigens for the Development of Serological Diagnosis of Marburg Fever

Проблемы особо опасных инфекций, 2021
Aim. Production of recombinant viral antigens of the main immunodominant proteins: glycoprotein (GPΔMLD), nucleoprotein (NP) and matrix protein (VP40) of the Marburg virus, as well as the study of their antigenic and immunogenic properties.Materials and ...
N. V. Volkova, A. V. Ivanova, A. A. Isaeva, O. A. Polezhaeva, A. V. Zaykovskaya, D. N. Shcherbakov, E. I. Kazachinskaya   +6 more
doaj   +1 more source

Clinical Manifestations and Case Management of Ebola Haemorrhagic Fever caused by a newly identified virus strain, Bundibugyo, Uganda, 2007-2008 [PDF]

, 2012
A confirmed Ebola haemorrhagic fever (EHF) outbreak in Bundibugyo, Uganda, November 2007-February 2008, was caused by a putative new species (Bundibugyo ebolavirus). It included 93 putative cases, 56 laboratory-confirmed cases, and 37 deaths (CFR = 25%).
A Grolla, A MacNeil, A Tuffs, AJ Georges, AM Casillas, B Jeffs, B Le Guenno, Benjamin Jeffs, BS Hewlett, DG Bausch, DG Bausch, DG Bausch, DG Bausch, DG Bausch, DH Smith, DL Heymann, E Mupere, ED Johnson, EM Leroy, EM Leroy, Esther Sterk, GA Martini, GA Martini, JL Conrad, Joseph Wamala, JS Gear, JS Towner, Julius Lutwama, K Kibadi, K Mupapa, K Mupapa, KJ Davis, M Borchert, M Bray, M Bray, MA Bwaka, Malcolm Gracie Semple, Maria D. Van Kerkhove, Matthias Borchert, ME Miranda, Michel Van Herp, MJ Bonnet, Natasha Howard, NK Jaax, P Formenty, P Formenty, P Francesconi, P Roddy, P Roddy, Paul Roddy, PE Rollin, Pedro Pablo Palma, PH Sureau, R Colebunders, R Ndambi, R Siegert, RC Baron, Robert Colebunders, RT Emond, S Becker, SF Dowell, SP Fisher-Hoch, SR Zaki, TH Roels, U Stroher, Y Kalongi, Zabulon Yoti   +66 more
core   +3 more sources

Paediatric acute liver failure: A prospective, nationwide, population‐based surveillance study in Germany

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Paediatric acute liver failure (PALF) is a rare but life‐threatening condition, yet comprehensive epidemiological data in Germany are lacking. Our study aimed to systematically analyse incidence, aetiology, and outcome of PALF in Germany.
Dominic Lenz, Muhammad Abdulaziz, Bianca Peters, Matias Wagner, Lea D. Schlieben, Victor M. Corman, Ulrich Baumann, Philip Bufler, Tal Dattner, Rainer Ganschow, Kristin Genzel, Nicole Hammann, Steffen Hartleif, Bianca Hegen, Stephan Henning, André Hoerning, Martin Jankofsky, Norman Junge, Simone Kathemann, Birgit Knoppke, Martina Kohl‐Sobania, Martin Laass, Elke Lainka, Eberhard Lurz, Michael Melter, Hanna Müller, Denisa Pilic, Markus Ries, Lisa Schiefele, Tobias Schwerd, Ekkehard Sturm, Mechtild Wegner, Michael S. Urschitz, Sven F. Garbade, Daniel Wenning, Christian Drosten, Alexander Fichtner, Stefan Kölker, Georg F. Hoffmann, Holger Prokisch, Christian Staufner   +40 more
wiley   +1 more source

Protection against Marburg Virus and Sudan Virus in NHP by an Adenovector-Based Trivalent Vaccine Regimen Is Correlated to Humoral Immune Response Levels

Vaccines, 2022
The Marburg virus (MARV) and Sudan virus (SUDV) belong to the filovirus family. The sporadic human outbreaks occur mostly in Africa and are characterized by an aggressive disease course with high mortality.
M. Tiemessen, L. Solforosi, Liesbeth Dekking, D. Czapska-Casey, Jan Serroyen, N. Sullivan, A. Volkmann, M. Pau, Benoît Callendret, H. Schuitemaker, K. Luhn, R. Zahn, R. Roozendaal   +12 more
semanticscholar   +1 more source

Six Injections of Modified Adjuvanted PQ Grass Is Effective and Well‐Tolerated in a Pivotal Phase III Trial

Allergy, EarlyView.
A pivotal Phase III DBPC adaptive trial was conducted with PQ Grass 27600 SU. The primary endpoint EAACI‐CSMS0–6 demonstrated a highly significant, clinically meaningful improvement for PQ Grass of −0.27 points (95% CI: −0.42 to −0.12), corresponding to a relative difference of −20.3% (p = 0.0005) over placebo. Highly consistent secondary endpoints and
Stefan Zielen, Jonathan A. Bernstein, Gunter J. Sturm, Marek Jutel, Oliver Pfaar, the RESONATE Investigator Group, R. Gattringer, K. Gangl, J. Potesil, T. Sykora, M. Mattauchova, P. Panzner, M. Kasl, Z. Chovancova, T. Hofstetr, J. Poloniova, A. Zlamal, J. Haas, F. Heimlich, C. Korte, S. Ballenberger, J. Grosskopf, P. Heymer, C. Bergmann, M. Froer, G. Hoheisel, U. Thieme, C. Grigat, U. Schaefer, P. El Naib, A. Schwinn, S. Runge, M. Worm, S. Pauser, M. Jandl, J.‐C. Bohn, C. von Engelhardt, A. Schaefer, J. Rieker‐Schwienbacher, M. Cuevas, S. Lassmann, Y. Yarin, T. Nyeky, I. Szanyi, V. Urban, J. Nemes, P. Borowy, Z. Siergiejko, E. Janusik, B. Tluczykont, D. Madra‐Rogacka, S. Ptaczek, I. Wojciechowska, J. Orlicz‐Widawska, M. Żurowska‐Gębala, T. Hofman, S. Tokarski, M. Bederska, A. Latos, K. Kowal, E. Markut‐Miotla, E. Pisarczyk‐Bogacka, P. Kuna, B. Majorek‐Olechowska, A. Chmielewska, B. Kucinska, C. Chwala, P. Parikh, J. Sublett, J. Weiss, J. Leflein, P. Shapero, D. McNeil, K. O’Brien, E. Sher, G. Steven, L. Ford, A. Darter, L. Clore, D. Elkayam, G. Myers, J. Matz, M. Vanderwalker, S. Smiley, J. DeAngelo, A. Montanaro, J. Delgado, W. Greisner, C. Thornblade, M. Moss, Mohamed H. Shamji, Ralph Mösges, Markus Berger, Uwe E. Berger, Lawrence DuBuske, Janice A. Layhadi, Ludger Klimek, Markus Ollert, Murray A. Skinner, Matthias F. Kramer, Pieter‐Jan de Kam   +100 more
wiley   +1 more source

Macaque models of human infectious disease. [PDF]

, 2008
Macaques have served as models for more than 70 human infectious diseases of diverse etiologies, including a multitude of agents-bacteria, viruses, fungi, parasites, prions.
Abe, Adams, Ahmed, Ajariyakhajorn, Albrecht, Allen, Apetrei, Apetrei, Arroyo, Bai, Bannantine, Barker, Barnett, Barouch, Baskerville, Baskin, Baze, Bennett, Blanchard, Blaney, Bons, Boonjakuakul, Breitschwerdt, Brooks, Brown, Bruce, Campos, Capone, Capone, Carbone, Carlson, Carlson, CARVALHO, Chan, Chattopadhyay, Chen, Chen, Chenine, Choi, Chomel, Choo, Chopra, Christe, Coalson, Coban, Cohen, Cohen, Contreras, Courgnaud, Custer, Cypess, Daddario-DiCaprio, Daddario-Dicaprio, Dalgard, Daniel, de Swart, Dezzutti, Di Giulio, Dittmer, Doi, Donnelly, Dubois, Dubois, Dutta, Earl, Edghill-Smith, Edghill-Smith, Ekanayake, Engel, Escalante, Espana, Farber, Feichtinger, Fisher-Hoch, Fisher-Hoch, Fitzgeorge, Fogg, Foley, Foucault, Fritz, Frolova, Gajdusek, Gallinella, Gao, Gardner, Gardner, Gardner, Gaynor, Geisbert, Geisbert, Geisbert, Geisbert, Gheit, Gibbs, Giddens, Goldstein, Gonder, Good, Gormus, Gormus, Goverdhan, Graczyk, Graff, Gray, Green, Guirakhoo, Haagmans, Haase, Habis, Hambleton, Hansen, Hawley, Heise, Heraud, Herzog, Hessell, Hicks, Higashi, Hirano, Hirsch, Hooper, Hotez, Hubbert, Hull, Hunsmann, Hutin, Ilyinskii, Inoue, Ivanoff, Jahrling, Ji, Johnson, Johnson, Jones-Engel, Jones-Engel, Kao, Kawai, Kawai, Kennedy, Kenyon, Kestler, Kinsey, Kishimoto, Klingstrom, Klumpp, Kobasa, Kobune, Kodama, Kornegay, Kuiken, Kuiken, Kunz, Kutok, Kwang, Lackner, Lake-Bakaar, Lasm  zas, Le Bras, Leong, Leroy, Letvin, Letvin, Letvin, Levine, Li, Li, Lichtenwalner, Lindsley, Line, Ling, Linial, Lockridge, Lodmell, Lowenstine, Lukashevich, Lukashevich, Lusso, Maddison, Mankowski, Mansfield, Mansfield, Marra, Marthas, Marthas, Marx, Mason, Masters, Matz-Rensing, Maul, McArthur-Vaughan, McMichael, McNeely, McShane, Meisenhelder, Mense, Miller, Miyoshi, Moghaddam, Monath, Mon  , Mooser, Morris, Morton, Mulder, Murphey-Corb, Murphy, Murphy, Myint, Nagle, NI, North, Novembre, O'Rourke, O'Sullivan, O'Sullivan, Olson, Ostrow, Ostrow, Oswald, Pachner, Pachner, Pachner, Pahar, Palmer, Palmer, Patton, Patton, Paul, Peiris, Percy, Perelygina, Permar, Persson, Peters, Peters, Petschow, Philipp, Philipp, Phipps, Pialoux, Pletnev, Polack, Pung, Puri, Raengsakulrach, Raether, Ratterree, Reed, Reimann, Reindel, Renne, Rhesus Macaque Genome Sequencing and Analysis Cons, Rimmelzwaan, Rimmelzwaan, Rivailler, Rockx, Rodas, Rue, Ruff, Russell, Saadat, Sale, Samuel, Sato, Schou, Schou, Schricker, Schultz, Sequar, Sestak, Shah, Shen, Shevtsova, Shuto, Simoes, Smit-McBride, Smith, Smith, Soike, Solnick, Solnick, Spencer, Stittelaar, Stittelaar, Stittelaar, Stokes, Subekti, Suss, Tanaka, Tanghe, Taylor, Taylor, Tribe, Tulis, Turell, Uberla, van den Hoogen, van Gorder, Van Heuverswyn, Van Rompay, Van Voorhis, Vasconcelos, Vasconcelos, Veazey, Voevodin, Vogel, Walsh, WALSH, Weinmann, Weiss, Wells, Wengelnik, Wenner, Westerman, White, Whitney, Williamson, Williamson, Willy, Wobus, Wolf, Wolfe, Wood, Wright, Wyatt, Xu, Yalcin, Zaucha, Zhou, Zuckerman, Zumpe   +330 more
core   +1 more source

Isolated Case of Marburg Virus Disease, Kampala, Uganda, 2014

Emerging Infectious Diseases, 2017
In September 2014, a single fatal case of Marburg virus was identified in a healthcare worker in Kampala, Uganda. The source of infection was not identified, and no secondary cases were identified.
Luke Nyakarahuka, Joseph Ojwang, Alex Tumusiime, Stephen Balinandi, Shannon Whitmer, Simon Kyazze, Sam Kasozi, Milton Wetaka, Issa Makumbi, Melissa Dahlke, Jeff Borchert, Julius Lutwama, Ute Ströher, Pierre E. Rollin, Stuart T. Nichol, Trevor R. Shoemaker   +15 more
doaj   +1 more source