Marburgvirus in Egyptian Fruit Bats, Zambia [PDF]
We detected Marburg virus genome in Egyptian fruit bats (Rousettus aegyptiacus) captured in Zambia in September 2018. The virus was closely related phylogenetically to the viruses that previously caused Marburg outbreaks in the Democratic Republic of the
Masahiro Kajihara +19 more
doaj +5 more sources
Recent advances in marburgvirus research [version 1; peer review: 3 approved] [PDF]
Marburgviruses are closely related to ebolaviruses and cause a devastating disease in humans. In 2012, we published a comprehensive review of the first 45 years of research on marburgviruses and the disease they cause, ranging from molecular biology to ...
Judith Olejnik +2 more
doaj +5 more sources
Discovery of common marburgvirus protective epitopes in a BALB/c mouse model [PDF]
Background Marburg virus (MARV) causes acute hemorrhagic fever that is often lethal, and no licensed vaccines are available for preventing this deadly viral infection.
Olinger Gene G +3 more
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Experimental Inoculation of Egyptian Rousette Bats (Rousettus aegyptiacus) with Viruses of the Ebolavirus and Marburgvirus Genera [PDF]
The Egyptian rousette bat (Rousettus aegyptiacus) is a natural reservoir for marburgviruses and a consistent source of virus spillover to humans. Cumulative evidence suggests various bat species may also transmit ebolaviruses.
Megan E.B. Jones +6 more
doaj +5 more sources
Filovirus RefSeq Entries: Evaluation and Selection of Filovirus Type Variants, Type Sequences, and Names [PDF]
Sequence determination of complete or coding-complete genomes of viruses is becoming common practice for supporting the work of epidemiologists, ecologists, virologists, and taxonomists.
Jens H. Kuhn +75 more
doaj +5 more sources
Preliminary Investigation of Schmalhausen’s Law in a Directly Transmitted Pathogen Outbreak System [PDF]
The past few decades have been marked by drastic modifications to the landscape by anthropogenic processes, leading to increased variability in the environment. For populations that thrive at their distributional boundaries, these changes can affect them
Antoine Filion +2 more
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Implementation of Objective PASC-Derived Taxon Demarcation Criteria for Official Classification of Filoviruses [PDF]
The mononegaviral family Filoviridae has eight members assigned to three genera and seven species. Until now, genus and species demarcation were based on arbitrarily chosen filovirus genome sequence divergence values (≈50% for genera, ≈30% for species ...
Yīmíng Bào +22 more
doaj +3 more sources
Periplasmic Nanobody-APEX2 Fusions Enable Facile Visualization of Ebola, Marburg, and Mĕnglà virus Nucleoproteins, Alluding to Similar Antigenic Landscapes among Marburgvirus and Dianlovirus [PDF]
We explore evolved soybean ascorbate peroxidase (APEX2) as a reporter when fused to the C-termini of llama nanobodies (single-domain antibodies, sdAb; variable domains of heavy chain-only antibodies, VHH) targeted to the E. coli periplasm.
Laura J. Sherwood, Andrew Hayhurst
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Development of a Pan-Filoviridae SYBR Green qPCR Assay for Biosurveillance Studies in Bats [PDF]
Recent studies have indicated that bats are hosts to diverse filoviruses. Currently, no pan-filovirus molecular assays are available that have been evaluated for the detection of all mammalian filoviruses.
Jessica Coertse +5 more
doaj +2 more sources
Increasing Occurrence of Marburg Virus Outbreaks in Africa: Risk Assessment for Public Health [PDF]
In this millennium, Marburgvirus (MARV) outbreaks with very high mortality but still small case numbers (
Harald Brüssow
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