Results 41 to 50 of about 1,760 (181)
Filovirus Entry: A Novelty in the Viral Fusion World
Ebolavirus (EBOV) and Marburgvirus (MARV) that compose the filovirus family of negative strand RNA viruses infect a broad range of mammalian cells.
Wendy Maury +2 more
doaj +1 more source
Assessing the feasibility of Phase 3 vaccine trials against Marburg Virus Disease: A modelling study
Background: Outbreaks of Marburg virus disease (MVD) are rare and small in size, with only 18 recorded outbreaks since 1967, only two of which involved more than 100 cases.
George Y. Qian +2 more
doaj +1 more source
Sequence determination of complete or coding-complete genomes of viruses is becoming common practice for supporting the work of epidemiologists, ecologists, virologists, and taxonomists.
Jens H. Kuhn +75 more
doaj +1 more source
Standardization of the Filovirus Plaque Assay for Use in Preclinical Studies
The filovirus plaque assay serves as the assay of choice to measure infectious virus in a cell culture, blood, or homogenized tissue sample. It has been in use for more than 30 years and is the generally accepted assay used to titrate virus in samples ...
Gene G. Olinger +10 more
doaj +1 more source
Recent outbreak of Marburg virus disease: Could it be a threat for global public health?
Health Science Reports, Volume 6, Issue 1, January 2023.
Md. Sohan +3 more
wiley +1 more source
Angola variant (MARV/Ang) has replaced Mt. Elgon variant Musoke isolate (MARV/MtE-Mus) as the consensus standard variant for Marburg virus research and is regarded as causing a more aggressive phenotype of disease in animal models; however, there is a ...
Paul W. Blair +9 more
doaj +1 more source
An Interagency Collaboration to Facilitate Development of Filovirus Medical Countermeasures
The Filovirus Animal Non-Clinical Group (FANG) is a US interdepartmental and interagency group established to support and facilitate the advanced development of filovirus Medical Countermeasures (MCM), both vaccines and therapeutics.
Edwin O. Nuzum, Nicole Kilgore
doaj +1 more source
Potential Vaccines and Post-Exposure Treatments for Filovirus Infections
Viruses of the family Filoviridae represent significant health risks as emerging infectious diseases as well as potentially engineered biothreats. While many research efforts have been published offering possibilities toward the mitigation of filoviral ...
Gene G. Olinger +6 more
doaj +1 more source
Additional file 1: Figure S1. Vaccine efficacy modelled as a function of days after vaccination. Figure S2. Serial interval, modelled as a gamma distribution. Figure S3. Number of secondary marburgvirus cases as a function of A.
Thibaut Jombart (250577) +3 more
core +1 more source
Background Marburg virus disease is an acute haemorrhagic fever caused by Marburg virus. Marburg virus is zoonotic, maintained in nature in Egyptian fruit bats, with occasional spillover infections into humans and nonhuman primates.
George Y. Qian +3 more
doaj +1 more source

