Results 41 to 50 of about 2,647 (192)

Standardization of the Filovirus Plaque Assay for Use in Preclinical Studies

Viruses, 2012
The filovirus plaque assay serves as the assay of choice to measure infectious virus in a cell culture, blood, or homogenized tissue sample. It has been in use for more than 30 years and is the generally accepted assay used to titrate virus in samples ...
Gene G. Olinger, Ana Kuehne, Jennifer L. Audet, Kendra J. Alfson, Anthony Griffiths, Holly A. Bloomfield, Elizabeth E. Zumbrun, Ashley E. Keeney, Julia E. Biggins, Amy C. Shurtleff, Sina Bavari   +10 more
doaj   +1 more source

Marburgvirus: A Global Virus, not just an African problem

Journal of Advances in Internal Medicine, 2023
The Marburg virus (MBV) phylogenetically belongs to the filovirus family and its clinical picture, spread and virulence resemble the Ebola virus very closely. The marked virulence of MBV is of great concern for not only the African region, but the globe in its entirety as a recent outbreak of the virus from a lab handling African green monkeys has ...
Jared Robinson, Indrajit Banerjee, Alexandra Leclézio   +2 more
openaire   +1 more source

Virulence of Marburg Virus Angola Compared to Mt. Elgon (Musoke) in Macaques: A Pooled Survival Analysis

Viruses, 2018
Angola variant (MARV/Ang) has replaced Mt. Elgon variant Musoke isolate (MARV/MtE-Mus) as the consensus standard variant for Marburg virus research and is regarded as causing a more aggressive phenotype of disease in animal models; however, there is a ...
Paul W. Blair, Maryam Keshtkar-Jahromi, Kevin J. Psoter, Ronald B. Reisler, Travis K. Warren, Sara C. Johnston, Arthur J. Goff, Lydia G. Downey, Sina Bavari, Anthony P. Cardile   +9 more
doaj   +1 more source

Lyophilisation of influenza, rabies and Marburg lentiviral pseudotype viruses for the development and distribution of a neutralisation-assay based diagnostic kit [PDF]

, 2014
Pseudotype viruses (PVs) are chimeric, replication-deficient virions that mimic wild-type virus entry mechanisms and can be safely employed in neutralisation assays, bypassing the need for high biosafety requirements and performing comparably to ...
Assar, Berge, Brauburger, Capecchi, Cliquet, Cox, Croyle, Demaison, Desvaux, Edward Wright, Fellowes, Gao, Higashikawa, Jackson, Kaku, Kishishita, Loi, Lowen, Mather, Molesti, Nigel J. Temperton, Noti, Papenburg, Pear, Scott, Scott, Shin, Simon D. Scott, Stoker, Stuart T. Mather, Temperton, Temperton, Terregino, To, Tong, Tyrrell, Wei, WHO, WHO, Wilschut, Wright, Wright, Wright, Yuen, Zufferey   +44 more
core   +3 more sources

A Call to Action to Enhance Filovirus Disease Outbreak Preparedness and Response

Viruses, 2014
The frequency and magnitude of recognized and declared filovirus-disease outbreaks have increased in recent years, while pathogenic filoviruses are potentially ubiquitous throughout sub-Saharan Africa.
Paul Roddy
doaj   +1 more source

Anticipating the species jump: surveillance for emerging viral threats. [PDF]

, 2012
Zoonotic disease surveillance is typically triggered after animal pathogens have already infected humans. Are there ways to identify high-risk viruses before they emerge in humans? If so, then how and where can identifications be made and by what methods?
Bush, RM, Cobey, S, Flanagan, ML, Glass, GE, Leighton, TJ, Parrish, CR   +5 more
core   +1 more source

A mathematical model of Marburg virus disease outbreaks and the potential role of vaccination in control

BMC Medicine, 2023
Background Marburg virus disease is an acute haemorrhagic fever caused by Marburg virus. Marburg virus is zoonotic, maintained in nature in Egyptian fruit bats, with occasional spillover infections into humans and nonhuman primates.
George Y. Qian, W. John Edmunds, Daniel G. Bausch, Thibaut Jombart   +3 more
doaj   +1 more source

Challenges, Progress, and Opportunities: Proceedings of the Filovirus Medical Countermeasures Workshop

Viruses, 2014
On August 22–23, 2013, agencies within the United States Department of Defense (DoD) and the Department of Health and Human Services (HHS) sponsored the Filovirus Medical Countermeasures (MCMs) Workshop as an extension of the activities of the Filovirus ...
Rona Hirschberg, Lucy A. Ward, Nicole Kilgore, Rebecca Kurnat, Helen Schiltz, Mark T. Albrecht, George W. Christopher, Ed Nuzum   +7 more
doaj   +1 more source

Isolation of Angola-like Marburg virus from Egyptian rousette bats from West Africa. [PDF]

, 2020
Marburg virus (MARV) causes sporadic outbreaks of severe Marburg virus disease (MVD). Most MVD outbreaks originated in East Africa and field studies in East Africa, South Africa, Zambia, and Gabon identified the Egyptian rousette bat (ERB; Rousettus ...
Amara, Emmanuel, Amman, Brian R, Bairoh, Fatmata V, Bakarr, Ibrahim A, Bangura, Abdulai A, Bangura, Camilla, Bangura, Doris, Bangura, James, Belaganahalli, Manjunatha, Bird, Brian H, Chow, Andrew, Conteh, Immah, Coomber, Moinya, Dhanota, Jasjeet, Edwin, Lavalie, Foday, Ibrahim, Gbakima, Aiah A, Gibson, Alexandra, Goldstein, Tracey, Graziano, James, Guetiya Wadoum, Raoul Emeric, Jambai, Amara, Johnny, Jonathan, Kamanda, Emmanuel S, Kamara, Sorie M, Kanu, Marilyn, Kanu, Osman, Kargbo, Dickson, Koroma, Alusine H, Lebbie, Aiah, Lungai, Victor, Mazet, Jonna AK, Mereweather-Thompson, Vanessa, Musa, Jonathan, Nichol, Stuart T, Ontiveros, Victoria, Osborne, Augustus, Patel, Ketan, Robert, Willie, Saidu, Emmanuel, Schuh, Amy J, Sealy, Tara K, Singh, Tushar, Taboy, Celine H, Towner, Jonathan S, Tremeau-Bravard, Alexandre, Turay, Joseph, Turay, Mohamed, Wadsworth, Richard, Williams, Samuel Maxwell Tom   +49 more
core  

Clinical Manifestations and Case Management of Ebola Haemorrhagic Fever caused by a newly identified virus strain, Bundibugyo, Uganda, 2007-2008 [PDF]

, 2012
A confirmed Ebola haemorrhagic fever (EHF) outbreak in Bundibugyo, Uganda, November 2007-February 2008, was caused by a putative new species (Bundibugyo ebolavirus). It included 93 putative cases, 56 laboratory-confirmed cases, and 37 deaths (CFR = 25%).
A Grolla, A MacNeil, A Tuffs, AJ Georges, AM Casillas, B Jeffs, B Le Guenno, Benjamin Jeffs, BS Hewlett, DG Bausch, DG Bausch, DG Bausch, DG Bausch, DG Bausch, DH Smith, DL Heymann, E Mupere, ED Johnson, EM Leroy, EM Leroy, Esther Sterk, GA Martini, GA Martini, JL Conrad, Joseph Wamala, JS Gear, JS Towner, Julius Lutwama, K Kibadi, K Mupapa, K Mupapa, KJ Davis, M Borchert, M Bray, M Bray, MA Bwaka, Malcolm Gracie Semple, Maria D. Van Kerkhove, Matthias Borchert, ME Miranda, Michel Van Herp, MJ Bonnet, Natasha Howard, NK Jaax, P Formenty, P Formenty, P Francesconi, P Roddy, P Roddy, Paul Roddy, PE Rollin, Pedro Pablo Palma, PH Sureau, R Colebunders, R Ndambi, R Siegert, RC Baron, Robert Colebunders, RT Emond, S Becker, SF Dowell, SP Fisher-Hoch, SR Zaki, TH Roels, U Stroher, Y Kalongi, Zabulon Yoti   +66 more
core   +3 more sources