Results 41 to 50 of about 1,751 (176)

Serological Evidence of Filovirus Infection in Nonhuman Primates in Zambia

open access: yesViruses, 2021
Ebolaviruses and marburgviruses are filoviruses that are known to cause severe hemorrhagic fever in humans and nonhuman primates (NHPs). While some bat species are suspected to be natural reservoirs of these filoviruses, wild NHPs often act as ...
Katendi Changula   +9 more
doaj   +1 more source

First‐ever Marburg virus disease outbreak in Equatorial Guinea and Tanzania: An imminent crisis in West and East Africa

open access: yesImmunity, Inflammation and Disease, Volume 11, Issue 8, August 2023., 2023
The Marburg virus causes the severe infectious disease known as Marburg Virus Disease (MVD). Previously, different outbreaks of MVD have appeared in different African countries. For the first time, Equatorial Guinea and Tanzania are experiencing MVD outbreaks.
Olivier Sibomana, Emmanuel Kubwimana
wiley   +1 more source

The recent outbreaks of Marburg virus disease in African countries are indicating potential threat to the global public health: Future prediction from historical data

open access: yesHealth Science Reports, Volume 6, Issue 7, July 2023., 2023
Abstract Marburg virus disease (MVD) caused by the Marburg virus has a high mortality rate. Rousettus aegyptiacus fruit bats act as the natural reservoir host of the virus. But it can also potentially be transmitted from person to person through direct contact with body secretions.
Iftekhar Ahmed   +5 more
wiley   +1 more source

Investigating Infectious Organisms of Public Health Concern Associated with Wild Meat

open access: yesTransboundary and Emerging Diseases, Volume 2023, Issue 1, 2023., 2023
The wild meat trade poses a significant threat to public health as it facilitates the spillover of zoonotic pathogens through high‐risk activities such as the hunting, butchering, trade, and consumption of wild animals. Despite the health risks and association with marking epidemics including SARS, Ebola, and COVID‐19, the global wild meat trade ...
Georgia Kate Moloney   +5 more
wiley   +1 more source

Marburgvirus: A Global Virus, not just an African problem

open access: yesJournal of Advances in Internal Medicine, 2023
The Marburg virus (MBV) phylogenetically belongs to the filovirus family and its clinical picture, spread and virulence resemble the Ebola virus very closely. The marked virulence of MBV is of great concern for not only the African region, but the globe in its entirety as a recent outbreak of the virus from a lab handling African green monkeys has ...
Jared Robinson   +2 more
openaire   +1 more source

Presentation of antigen on extracellular vesicles using transmembrane domains from viral glycoproteins for enhanced immunogenicity

open access: yesJournal of Extracellular Vesicles, Volume 11, Issue 3, March 2022., 2022
Abstract A vaccine antigen, when launched as DNA or RNA, can be presented in various forms, including intracellular, secreted, membrane‐bound, or on extracellular vesicles (EVs). Whether an antigen in one or more of these forms is superior in immune induction remains unclear.
Kai Hu   +9 more
wiley   +1 more source

Plasmodium berghei‐Mediated NRF2 Activation in Infected Hepatocytes Enhances Parasite Survival

open access: yesCellular Microbiology, Volume 2022, Issue 1, 2022., 2022
The protozoan parasite Plasmodium, causative agent of malaria, initially invades and develops in hepatocytes where it resides in a parasitophorous vacuole (PV). A single invaded parasite develops into thousands of daughter parasites. Survival of the host cell is crucial for successful completion of liver stage development.
Annina Bindschedler   +7 more
wiley   +1 more source

Filovirus Entry: A Novelty in the Viral Fusion World

open access: yesViruses, 2012
Ebolavirus (EBOV) and Marburgvirus (MARV) that compose the filovirus family of negative strand RNA viruses infect a broad range of mammalian cells.
Wendy Maury   +2 more
doaj   +1 more source

Assessing the feasibility of Phase 3 vaccine trials against Marburg Virus Disease: A modelling study

open access: yesVaccine: X, 2023
Background: Outbreaks of Marburg virus disease (MVD) are rare and small in size, with only 18 recorded outbreaks since 1967, only two of which involved more than 100 cases.
George Y. Qian   +2 more
doaj   +1 more source

Filovirus RefSeq Entries: Evaluation and Selection of Filovirus Type Variants, Type Sequences, and Names

open access: yesViruses, 2014
Sequence determination of complete or coding-complete genomes of viruses is becoming common practice for supporting the work of epidemiologists, ecologists, virologists, and taxonomists.
Jens H. Kuhn   +75 more
doaj   +1 more source

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