Results 61 to 70 of about 2,647 (192)

The Study of Viral RNA Diversity in Bird Samples Using De Novo Designed Multiplex Genus‐Specific Primer Panels

Advances in Virology, Volume 2018, Issue 1, 2018., 2018
Advances in the next generation sequencing (NGS) technologies have significantly increased our ability to detect new viral pathogens and systematically determine the spectrum of viruses prevalent in various biological samples. In addition, this approach has also helped in establishing the associations of viromes with many diseases.
Andrey A. Ayginin, Ekaterina V. Pimkina, Alina D. Matsvay, Anna S. Speranskaya, Marina V. Safonova, Ekaterina A. Blinova, Ilya V. Artyushin, Vladimir G. Dedkov, German A. Shipulin, Kamil Khafizov, Gary S. Hayward   +10 more
wiley   +1 more source

Single-Dose Trivalent VesiculoVax Vaccine Protects Macaques from Lethal Ebolavirus and Marburgvirus Challenge [PDF]

Journal of Virology, 2018
ABSTRACT Previous studies demonstrated that a single intramuscular (i.m.) dose of an attenuated recombinant vesicular stomatitis virus (rVSV) vector (VesiculoVax vector platform; rVSV-N4CT1) expressing the glycoprotein (GP) from the Mayinga strain of Zaire ebolavirus (EBOV ...
Demetrius, Matassov, Chad E, Mire, Theresa, Latham, Joan B, Geisbert, Rong, Xu, Ayuko, Ota-Setlik, Krystle N, Agans, Dean J, Kobs, Morgan Q S, Wendling, Amanda, Burnaugh, Thomas L, Rudge, Carol L, Sabourin, Michael A, Egan, David K, Clarke, Thomas W, Geisbert, John H, Eldridge   +15 more
openaire   +2 more sources

The role of cellular adhesion molecules in virus attachment and entry [PDF]

, 2015
As obligate intracellular parasites, viruses must traverse the host-cell plasma membrane to initiate infection. This presents a formidable barrier, which they have evolved diverse strategies to overcome.
Bhella, David
core   +1 more source

Living with Bats: The Case of Ve Golokuati Township in the Volta Region of Ghana

Journal of Environmental and Public Health, Volume 2017, Issue 1, 2017., 2017
Transmission of zoonotic pathogens from bats to humans through direct and indirect contact with bats raises public apprehension about living close to bats. In the township of Ve Golokuati in Ghana, several “camps” of Epomophorus gambianus roost in fruit trees that provide ecosystems services for residents.
Jesse S. Ayivor, Fidelia Ohemeng, Elaine Tweneboah Lawson, Linda Waldman, Melissa Leach, Yaa Ntiamoa-Baidu, Tongzhang Zheng   +6 more
wiley   +1 more source

Vaccinomics strategy for developing a unique multi-epitope monovalent vaccine against Marburg marburgvirus [PDF]

Infection, Genetics and Evolution, 2018
Marburg virus causes severe hemorrhagic fever in both humans and non-human primates with high degree of infectivity and lethality. To date no approved treatment is available for Marburg virus infection. A study was employed to design a novel chimeric vaccine against Marburg virus by adopting reverse vaccinology approach.
Hasan, Mahmudul, Azim, Kazi Faizul, Begum, Aklima, Khan, Noushin Anika, Shammi, Tasfia Saiyara, Imran, Md. Abdus Shukur, Chowdhury, Ishtiak Malique, Urme, Shah Rucksana Akhter   +7 more
openaire   +2 more sources

Outbreak of Marburg hemorrhagic fever among miners in Kamwenge and Ibanda Districts, Uganda, 2007 [PDF]

, 2011
Marburg hemorrhagic fever was detected among 4 miners in Ibanda District, Uganda, from June through September, 2007. Infection was likely acquired through exposure to bats or bat secretions in a mine in Kamwenge District, Uganda, and possibly human-to ...
Atek Kagirita, Bausch, Bausch, Ben Jeffs, Brian Amman, Centers for Disease Control and Prevention, Centers for Disease Control and Prevention, Craig Manning, Edgar Kansiime, Eileen C. Farnon, Emmanuel Byaruhanga, F. Katunguka, Florimond Tschioko, Godfrey S. Bwire, Jennifer Adjemian, Jentes, Jonathan Towner, Jordan W. Tappero, Joseph F. Wamala, Julius J. Lutwama, Pierre E. Rollin, Pierre Formenty, Robert Downing, Sam Ahimbisibwe, Stuart T. Nichol, Swanepoel, Taylor, Timen, Towner, Towner, Wahl-Jensen, World Health Organization   +31 more
core   +2 more sources

Marburg virus outbreaks in Africa

Bulletin of the National Research Centre, 2023
Marburg virus disease (MVD) is a zoonotic viral hemorrhagic illness, caused by a negative sense, single-stranded RNA virus which has an envelope. The Marburg virus belongs to the genus Marburgvirus of the family Filoviridae.
Ibrahim Idris, Ridwan Olamilekan Adesola, Joanna Nicole D’Souza   +2 more
doaj   +1 more source

Effective Binding of a Phosphatidylserine‐Targeting Antibody to Ebola Virus Infected Cells and Purified Virions

Journal of Immunology Research, Volume 2015, Issue 1, 2015., 2015
Ebola virus is responsible for causing severe hemorrhagic fevers, with case fatality rates of up to 90%. Currently, no antiviral or vaccine is licensed against Ebola virus. A phosphatidylserine‐targeting antibody (PGN401, bavituximab) has previously been shown to have broad‐spectrum antiviral activity.
S. D. Dowall, V. A. Graham, K. Corbin-Lickfett, C. Empig, K. Schlunegger, C. B. Bruce, L. Easterbrook, R. Hewson, Caroline Rowland   +8 more
wiley   +1 more source

Factors Associated with Marburg Hemorrhagic Fever: [PDF]

, 2010
Background. Reliable on-site polymerase chain reaction (PCR) testing for Marburg hemorrhagic fever (MHF) is not always available. Therefore, clinicians triage patients on the basis of presenting symptoms and contact history.
Bengi Moco Henrique, Benjamin Jeffs, Fernando Paixao Damiao Machado, Heinz Feldmann, James E. Strong, Luis Villa, Matthias Borchert, Oscar Bernal, Pascoal Nascimento Folo, Pedro Pablo Palma, Roddy, Paul, Sara L Thomas, Steven M. Jones   +12 more
core   +2 more sources

Land Use Change and Infectious Disease Emergence

Reviews of Geophysics, Volume 63, Issue 2, June 2025.
Abstract Major infectious diseases threatening human health are transmitted to people from animals or by arthropod vectors such as insects. In recent decades, disease outbreaks have become more common, especially in tropical regions, including new and emerging infections that were previously undetected or unknown. Even though there is growing awareness
M. Cristina Rulli, Paolo D’Odorico, Nikolas Galli, Reju S. John, Renata L. Muylaert, Monia Santini, David T. S. Hayman   +6 more
wiley   +1 more source