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Filovirus Outbreaks in Central Africa.
, 2022 Mbandaka was the site of two EBOV outbreaks: 2018 (54 cases) and 2020 (130 cases). Other outbreaks in the northwestern DRC occurred in: Yambuku (1976; 318 cases; 540 km from Mbandaka), Tandala (1977; 1 case; 350 km), Boende (2014; 69 cases; 300 km) and ...
Brandyn R. West (12206976) +18 more
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A Call to Action to Enhance Filovirus Disease Outbreak Preparedness and Response
Viruses, 2014 The frequency and magnitude of recognized and declared filovirus-disease outbreaks have increased in recent years, while pathogenic filoviruses are potentially ubiquitous throughout sub-Saharan Africa.
Paul Roddy
doaj +1 more source
Novel Small Molecule Therapeutics and Mechanisms of Action for the Treatment of Filovirus Diseases [PDF]
, 2021 Filoviruses are among the deadliest diseases known to mankind with mortality rates up to 90%. Furthermore, new filoviruses are being discovered in areas such as China where they had not previously been reported.
Adam Michael Schafer (11298372)
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Viruses, 2017 The mononegaviral family Filoviridae has eight members assigned to three genera and seven species. Until now, genus and species demarcation were based on arbitrarily chosen filovirus genome sequence divergence values (≈50% for genera, ≈30% for species ...
Yīmíng Bào +22 more
doaj +1 more source
Evidence that ebolaviruses and cuevaviruses have been diverging from marburgviruses since the Miocene [PDF]
PeerJ, 2014 An understanding of the timescale of evolution is critical for comparative virology but remains elusive for many RNA viruses. Age estimates based on mutation rates can severely underestimate divergences for ancient viral genes that are evolving under ...
Derek J. Taylor +4 more
doaj +2 more sources
Viruses, 2014 On August 22–23, 2013, agencies within the United States Department of Defense (DoD) and the Department of Health and Human Services (HHS) sponsored the Filovirus Medical Countermeasures (MCMs) Workshop as an extension of the activities of the Filovirus ...
Rona Hirschberg +7 more
doaj +1 more source
MicroorganismsFiloviruses are among the most lethal viral human pathogens known, with significant relevance to public health, yet their evolutionary history remains poorly resolved.
Thiago S. Messias +15 more
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Advances in Virology, Volume 2018, Issue 1, 2018., 2018 Advances in the next generation sequencing (NGS) technologies have significantly increased our ability to detect new viral pathogens and systematically determine the spectrum of viruses prevalent in various biological samples. In addition, this approach has also helped in establishing the associations of viromes with many diseases.
Andrey A. Ayginin +10 more
wiley +1 more source
Cohorts of immature Pteropus bats show interannual variation in Hendra virus serology
Journal of Animal Ecology, Volume 95, Issue 3, Page 521-537, March 2026.Pteropus bat with offspring, photo taken by Manuel Ruiz‐Aravena. Abstract Understanding the drivers of seasonal disease outbreaks remains a fundamental challenge in disease ecology. Periodic outbreaks can be driven by several seasonally varying factors, including pulses of susceptible individuals through births, changes in host behaviour and social ...
Daniel E. Crowley +24 more
wiley +1 more source
Marburg virus outbreaks in Africa
Bulletin of the National Research Centre, 2023 Marburg virus disease (MVD) is a zoonotic viral hemorrhagic illness, caused by a negative sense, single-stranded RNA virus which has an envelope. The Marburg virus belongs to the genus Marburgvirus of the family Filoviridae.
Ibrahim Idris +2 more
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