Results 51 to 60 of about 1,751 (176)
Standardization of the Filovirus Plaque Assay for Use in Preclinical Studies
Viruses, 2012 The filovirus plaque assay serves as the assay of choice to measure infectious virus in a cell culture, blood, or homogenized tissue sample. It has been in use for more than 30 years and is the generally accepted assay used to titrate virus in samples ...
Gene G. Olinger +10 more
doaj +1 more source
Recent outbreak of Marburg virus disease: Could it be a threat for global public health?
, 2023 Health Science Reports, Volume 6, Issue 1, January 2023.
Md. Sohan +3 more
wiley +1 more source
Viruses, 2018 Angola variant (MARV/Ang) has replaced Mt. Elgon variant Musoke isolate (MARV/MtE-Mus) as the consensus standard variant for Marburg virus research and is regarded as causing a more aggressive phenotype of disease in animal models; however, there is a ...
Paul W. Blair +9 more
doaj +1 more source
An Interagency Collaboration to Facilitate Development of Filovirus Medical Countermeasures
Viruses, 2012 The Filovirus Animal Non-Clinical Group (FANG) is a US interdepartmental and interagency group established to support and facilitate the advanced development of filovirus Medical Countermeasures (MCM), both vaccines and therapeutics.
Edwin O. Nuzum, Nicole Kilgore
doaj +1 more source
Potential Vaccines and Post-Exposure Treatments for Filovirus Infections
Viruses, 2012 Viruses of the family Filoviridae represent significant health risks as emerging infectious diseases as well as potentially engineered biothreats. While many research efforts have been published offering possibilities toward the mitigation of filoviral ...
Gene G. Olinger +6 more
doaj +1 more source
BMC Medicine, 2023 Background Marburg virus disease is an acute haemorrhagic fever caused by Marburg virus. Marburg virus is zoonotic, maintained in nature in Egyptian fruit bats, with occasional spillover infections into humans and nonhuman primates.
George Y. Qian +3 more
doaj +1 more source
A Call to Action to Enhance Filovirus Disease Outbreak Preparedness and Response
Viruses, 2014 The frequency and magnitude of recognized and declared filovirus-disease outbreaks have increased in recent years, while pathogenic filoviruses are potentially ubiquitous throughout sub-Saharan Africa.
Paul Roddy
doaj +1 more source
Homo-Oligomerization of Marburgvirus VP35 Is Essential for Its Function in Replication and Transcription [PDF]
Journal of Virology, 2005 ABSTRACT The nucleocapsid protein VP35 of Marburgvirus, a filovirus, acts as the cofactor of the viral polymerase and plays an essential role in transcription and replication of the viral RNA. VP35 forms complexes with the genome encapsidating protein NP and with the RNA-dependent RNA polymerase L.
Peggy, Möller +3 more
openaire +2 more sources
Shedding of Marburg Virus in Naturally Infected Egyptian Rousette Bats, South Africa, 2017 [PDF]
, 2020 We detected Marburg virus RNA in rectal swab samples from Egyptian rousette bats in South Africa in 2017. This finding signifies that fecal contamination of natural bat habitats is a potential source of infection for humans.
Palacios, G. +12 more
core +1 more source
Viruses, 2017 The mononegaviral family Filoviridae has eight members assigned to three genera and seven species. Until now, genus and species demarcation were based on arbitrarily chosen filovirus genome sequence divergence values (≈50% for genera, ≈30% for species ...
Yīmíng Bào +22 more
doaj +1 more source