Results 31 to 40 of about 1,487 (150)
Animal models for Ebola and Marburg virus infections
Frontiers in Microbiology, 2013 Ebola and Marburg hemorrhagic fevers (EHF and MHF) are caused by the Filoviridae family, Ebolavirus and Marburgvirus (ebolavirus and marburgvirus), respectively. These severe diseases have high mortality rates in humans.
Eri eNakayama, Masayuki eSaijo
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Filovirus Entry: A Novelty in the Viral Fusion World
Viruses, 2012 Ebolavirus (EBOV) and Marburgvirus (MARV) that compose the filovirus family of negative strand RNA viruses infect a broad range of mammalian cells.
Wendy Maury +2 more
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Assessing the feasibility of Phase 3 vaccine trials against Marburg Virus Disease: A modelling study
Vaccine: X, 2023 Background: Outbreaks of Marburg virus disease (MVD) are rare and small in size, with only 18 recorded outbreaks since 1967, only two of which involved more than 100 cases.
George Y. Qian +2 more
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Viruses, 2014 Sequence determination of complete or coding-complete genomes of viruses is becoming common practice for supporting the work of epidemiologists, ecologists, virologists, and taxonomists.
Jens H. Kuhn +75 more
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Standardization of the Filovirus Plaque Assay for Use in Preclinical Studies
Viruses, 2012 The filovirus plaque assay serves as the assay of choice to measure infectious virus in a cell culture, blood, or homogenized tissue sample. It has been in use for more than 30 years and is the generally accepted assay used to titrate virus in samples ...
Gene G. Olinger +10 more
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Recent outbreak of Marburg virus disease: Could it be a threat for global public health?
, 2023 Health Science Reports, Volume 6, Issue 1, January 2023.
Md. Sohan +3 more
wiley +1 more source
Viruses, 2018 Angola variant (MARV/Ang) has replaced Mt. Elgon variant Musoke isolate (MARV/MtE-Mus) as the consensus standard variant for Marburg virus research and is regarded as causing a more aggressive phenotype of disease in animal models; however, there is a ...
Paul W. Blair +9 more
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An Interagency Collaboration to Facilitate Development of Filovirus Medical Countermeasures
Viruses, 2012 The Filovirus Animal Non-Clinical Group (FANG) is a US interdepartmental and interagency group established to support and facilitate the advanced development of filovirus Medical Countermeasures (MCM), both vaccines and therapeutics.
Edwin O. Nuzum, Nicole Kilgore
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Ebolavirus Δ-Peptide Immunoadhesins Inhibit Marburgvirus and Ebolavirus Cell Entry [PDF]
Journal of Virology, 2011 ABSTRACT With the exception of Reston and Lloviu viruses, filoviruses (marburgviruses, ebolaviruses, and “cuevaviruses”) cause severe viral hemorrhagic fevers in humans. Filoviruses use a class I fusion protein, GP 1,2 , to bind to an unknown, but shared, cell surface receptor to initiate virus-cell fusion.
Sheli R, Radoshitzky +18 more
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Potential Vaccines and Post-Exposure Treatments for Filovirus Infections
Viruses, 2012 Viruses of the family Filoviridae represent significant health risks as emerging infectious diseases as well as potentially engineered biothreats. While many research efforts have been published offering possibilities toward the mitigation of filoviral ...
Gene G. Olinger +6 more
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