Results 11 to 20 of about 1,760 (181)

Recent advances in marburgvirus research [version 1; peer review: 3 approved] [PDF]

open access: yesF1000Research, 2019
Marburgviruses are closely related to ebolaviruses and cause a devastating disease in humans. In 2012, we published a comprehensive review of the first 45 years of research on marburgviruses and the disease they cause, ranging from molecular biology to ...
Judith Olejnik   +2 more
doaj   +6 more sources

Animal models for Ebola and Marburg virus infections [PDF]

open access: yesFrontiers in Microbiology, 2013
Ebola and Marburg hemorrhagic fevers (EHF and MHF) are caused by the Filoviridae family, Ebolavirus and Marburgvirus (ebolavirus and marburgvirus), respectively. These severe diseases have high mortality rates in humans.
Eri eNakayama, Masayuki eSaijo
doaj   +2 more sources

Periplasmic Nanobody-APEX2 Fusions Enable Facile Visualization of Ebola, Marburg, and Mĕnglà virus Nucleoproteins, Alluding to Similar Antigenic Landscapes among Marburgvirus and Dianlovirus

open access: yesViruses, 2019
We explore evolved soybean ascorbate peroxidase (APEX2) as a reporter when fused to the C-termini of llama nanobodies (single-domain antibodies, sdAb; variable domains of heavy chain-only antibodies, VHH) targeted to the E. coli periplasm.
Laura J. Sherwood, Andrew Hayhurst
doaj   +2 more sources

Marburgvirus in Egyptian Fruit Bats, Zambia [PDF]

open access: yesEmerging Infectious Diseases, 2019
We detected Marburg virus genome in Egyptian fruit bats (Rousettus aegyptiacus) captured in Zambia in September 2018. The virus was closely related phylogenetically to the viruses that previously caused Marburg outbreaks in the Democratic Republic of the
Masahiro Kajihara   +19 more
doaj   +4 more sources

Ebolavirus Δ-Peptide Immunoadhesins Inhibit Marburgvirus and Ebolavirus Cell Entry [PDF]

open access: yesJournal of Virology, 2011
ABSTRACT With the exception of Reston and Lloviu viruses, filoviruses (marburgviruses, ebolaviruses, and “cuevaviruses”) cause severe viral hemorrhagic fevers in humans. Filoviruses use a class I fusion protein, GP 1,2 , to bind to an unknown, but shared, cell surface receptor to initiate virus-cell fusion.
Sheli R, Radoshitzky   +18 more
openaire   +3 more sources

Marburgvirus Resurgence in Kitaka Mine Bat Population After Extermination Attempts, Uganda.

open access: yesEmerging Infectious Diseases, 2014
To the Editor: Marburg virus (MARV) and Ravn virus (RAVV), collectively called marburgviruses, cause Marburg hemorrhagic fever (MHF) in humans. In July 2007, 4 cases of MHF (1 fatal) occurred in miners at Kitaka Mine in southern Uganda. Later, MHF occurred in 2 tourists who visited Python Cave, ≈50 km from Kitaka Mine.
Anita McElroy   +2 more
exaly   +5 more sources

Unveiling a Drift Resistant Cryptotope within Marburgvirus Nucleoprotein Recognized by Llama Single-Domain Antibodies [PDF]

open access: yesFrontiers in Immunology, 2017
Marburg virus (MARV) is a highly lethal hemorrhagic fever virus that is increasingly re-emerging in Africa, has been imported to both Europe and the US, and is also a Tier 1 bioterror threat.
John Anthony Garza   +5 more
doaj   +2 more sources

Discovery of common marburgvirus protective epitopes in a BALB/c mouse model [PDF]

open access: yesVirology Journal, 2009
Background Marburg virus (MARV) causes acute hemorrhagic fever that is often lethal, and no licensed vaccines are available for preventing this deadly viral infection.
Olinger Gene G   +3 more
doaj   +3 more sources

Untersuchungen zur Rolle des VP24 im Vermehrungszyklus des Marburgvirus

open access: yes, 2005
The highly pathogenic enveloped Marburgvirus (MARV) is composed of seven structural proteins and the nonsegmented negative-sensed viral RNA genome. Four proteins (NP, VP35, VP30, and L) make up the helical nucleocapsid complex which is surrounded by a matrix that is composed of VP40 and VP24.
Bamberg, Sandra (129898848)
core   +4 more sources

Development of a model for marburgvirus based on severe-combined immunodeficiency mice [PDF]

open access: yesVirology Journal, 2007
The filoviruses, Ebola (EBOV) and Marburg (MARV), cause a lethal hemorrhagic fever. Human isolates of MARV are not lethal to immmunocompetent adult mice and, to date, there are no reports of a mouse-adapted MARV model. Previously, a uniformly lethal EBOV-
Kalina Warren V   +7 more
doaj   +3 more sources

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