Results 81 to 90 of about 1,760 (181)

Coverage robustness.

open access: yes, 2012
The coverage of new protein set viral diversity of nucleoprotein (NP) and glycoprotein (GP) by vaccines designed against original and new protein sequence sets for both mosaic cocktails and best-natural cocktails.
Paul W. Fenimore (131047)   +12 more
core   +1 more source

Filoviruses in Bats: Current Knowledge and Future Directions

open access: yesViruses, 2014
Filoviruses, including Ebolavirus and Marburgvirus, pose significant threats to public health and species conservation by causing hemorrhagic fever outbreaks with high mortality rates. Since the first outbreak in 1967, their origins, natural history, and
Kevin J. Olival, David T. S. Hayman
doaj   +1 more source

Ebolavirus and Marburgvirus Infections [PDF]

open access: yes, 2016
Ebolaviruses and marburgviruses are incompletely understood pathogens that cause severe, often fatal, illnesses in humans and non-human primates. These diseases have been known as Ebola and Marburg hemorrhagic fevers, respectively, after the most ...

core  

Cross-species binding of filovirus VP30 and NP.

open access: yes, 2016
ITC experiments were carried out using EBOV, SUDV or MARV VP30 CTD (ebolavirus 139–288 or Marburgvirus 146–281) and EBOV, SUDV or MARV NP peptide (ebolavirus 600–617 or Marburg virus 552–569) fused to T4 lysozyme. Equilibrium dissociation constants (KDs)
Robert N. Kirchdoerfer (2418154)   +3 more
core   +1 more source

Serological Detection of Ebola Virus Exposures in Native Non-human Primates of Southern Nigeria

open access: yesJournal of Epidemiology and Global Health, 2018
Ebola viruses (family: Filoviridae) are the cause of Ebola virus disease (EVD), a highly fatal illness characterised by haemorrhagic fever syndrome in both humans and non-human primates (NHPs).
B.N. Ogunro   +5 more
doaj   +1 more source

T-cell immunoglobulin and mucin domain 1 (TIM-1) is a receptor for Zaire Ebolavirus and Lake Victoria Marburgvirus

open access: yes, 2011
The glycoproteins (GP) of enveloped viruses facilitate entry into the host cell by interacting with specific cellular receptors. Despite extensive study, a cellular receptor for the deadly filoviruses Ebolavirus and
Paul Rennert   +15 more
core   +1 more source

Diagnostic reverse-transcription polymerase chain reaction kit for filoviruses based on the strain collections of all European biosafety level 4 laboratories

open access: yes, 2007
A network of European biosafety level 4 laboratories has designed the first industry-standard molecular assay for all filoviruses species, based on the strain collections of all participants. It uses 5 optimized L gene primers and 3 probes, as well as an
Panning, M   +9 more
core   +1 more source

Deep Sequencing Identifies Noncanonical Editing of Ebola and Marburg Virus RNAs in Infected Cells

open access: yesmBio, 2014
Deep sequencing of RNAs produced by Zaire ebolavirus (EBOV) or the Angola strain of Marburgvirus (MARV-Ang) identified novel viral and cellular mechanisms that diversify the coding and noncoding sequences of viral mRNAs and genomic RNAs.
Reed S. Shabman   +7 more
doaj   +1 more source

Thermostable bivalent filovirus vaccine protects against severe and lethal Sudan ebolavirus and marburgvirus infection. [PDF]

open access: yesVaccine
Although two vaccines for Zaire ebolavirus (EBOV) have been licensed and deployed successfully to combat recurring outbreaks of Ebolavirus Disease in West Africa, there are no vaccines for two other highly pathogenic members of the Filoviridae, Sudan ebolavirus (SUDV) and Marburg marburgvirus (MARV).
To A   +16 more
europepmc   +3 more sources

Filiviruses of southeast Asia, China and Europe (review)

open access: yesЖурнал инфектологии, 2019
Filoviruses are known as causative agents of severe haemorrhagic fevers with a high mortality rate in humans. Zaire ebolavirus and Marburgvirus, the most known of them, are associated with the occurrence of sporadic cases and outbreaks of hemorrhagic ...
A. M. Porshakov   +2 more
doaj   +1 more source

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