Results 81 to 90 of about 1,760 (181)
The coverage of new protein set viral diversity of nucleoprotein (NP) and glycoprotein (GP) by vaccines designed against original and new protein sequence sets for both mosaic cocktails and best-natural cocktails.
Paul W. Fenimore (131047) +12 more
core +1 more source
Filoviruses in Bats: Current Knowledge and Future Directions
Filoviruses, including Ebolavirus and Marburgvirus, pose significant threats to public health and species conservation by causing hemorrhagic fever outbreaks with high mortality rates. Since the first outbreak in 1967, their origins, natural history, and
Kevin J. Olival, David T. S. Hayman
doaj +1 more source
Ebolavirus and Marburgvirus Infections [PDF]
Ebolaviruses and marburgviruses are incompletely understood pathogens that cause severe, often fatal, illnesses in humans and non-human primates. These diseases have been known as Ebola and Marburg hemorrhagic fevers, respectively, after the most ...
core
Cross-species binding of filovirus VP30 and NP.
ITC experiments were carried out using EBOV, SUDV or MARV VP30 CTD (ebolavirus 139–288 or Marburgvirus 146–281) and EBOV, SUDV or MARV NP peptide (ebolavirus 600–617 or Marburg virus 552–569) fused to T4 lysozyme. Equilibrium dissociation constants (KDs)
Robert N. Kirchdoerfer (2418154) +3 more
core +1 more source
Serological Detection of Ebola Virus Exposures in Native Non-human Primates of Southern Nigeria
Ebola viruses (family: Filoviridae) are the cause of Ebola virus disease (EVD), a highly fatal illness characterised by haemorrhagic fever syndrome in both humans and non-human primates (NHPs).
B.N. Ogunro +5 more
doaj +1 more source
The glycoproteins (GP) of enveloped viruses facilitate entry into the host cell by interacting with specific cellular receptors. Despite extensive study, a cellular receptor for the deadly filoviruses Ebolavirus and
Paul Rennert +15 more
core +1 more source
A network of European biosafety level 4 laboratories has designed the first industry-standard molecular assay for all filoviruses species, based on the strain collections of all participants. It uses 5 optimized L gene primers and 3 probes, as well as an
Panning, M +9 more
core +1 more source
Deep Sequencing Identifies Noncanonical Editing of Ebola and Marburg Virus RNAs in Infected Cells
Deep sequencing of RNAs produced by Zaire ebolavirus (EBOV) or the Angola strain of Marburgvirus (MARV-Ang) identified novel viral and cellular mechanisms that diversify the coding and noncoding sequences of viral mRNAs and genomic RNAs.
Reed S. Shabman +7 more
doaj +1 more source
Thermostable bivalent filovirus vaccine protects against severe and lethal Sudan ebolavirus and marburgvirus infection. [PDF]
Although two vaccines for Zaire ebolavirus (EBOV) have been licensed and deployed successfully to combat recurring outbreaks of Ebolavirus Disease in West Africa, there are no vaccines for two other highly pathogenic members of the Filoviridae, Sudan ebolavirus (SUDV) and Marburg marburgvirus (MARV).
To A +16 more
europepmc +3 more sources
Filiviruses of southeast Asia, China and Europe (review)
Filoviruses are known as causative agents of severe haemorrhagic fevers with a high mortality rate in humans. Zaire ebolavirus and Marburgvirus, the most known of them, are associated with the occurrence of sporadic cases and outbreaks of hemorrhagic ...
A. M. Porshakov +2 more
doaj +1 more source

