Need of surveillance response systems to combat Ebola outbreaks and other emerging infectious diseases in African countries [PDF]
, 2014 There is growing concern in Sub-Saharan Africa about the spread of the Ebola virus disease (EVD), formerly known as Ebola haemorrhagic fever, and the public health burden that it ensues.
Emmanuel Ugwu +2 more
core +10 more sources
Introducing EbolaCheck: potential for point-of-need infectious disease diagnosis [PDF]
, 2015 The 2013–2015 Ebolavirus disease humanitarian crisis has spurred the development of laboratory-free, point-of-care nucleic acid testing solutions.
Christie A +6 more
core +1 more source
Evolutionary maintenance of filovirus-like genes in bat genomes
BMC Evolutionary Biology, 2011 Background Little is known of the biological significance and evolutionary maintenance of integrated non-retroviral RNA virus genes in eukaryotic host genomes.
Taylor Derek J +3 more
doaj +1 more source
Charakterisierung der Rolle des endosomalen Recycling-Systems für den intrazellulären Transport des Marburg Virus Glykoproteins [PDF]
, 2019 Das Marburg Virus (MARV), das zur Familie der Filoviridae gezählt wird, ist ein Erreger schwerer Fieber mit Letalitätsraten von bis zu 90 %. Das Glykoprotein GP stellt das einzige Oberflächenprotein des MARV dar und daher ist sein korrekter Transport zu ...
Halwe, Sandro
core +1 more source
Die IRE1-abhängige ER-Stress-Antwort wird durch antagonistische Effekte der Marburg Virus Proteine GP und VP30 ausbalanciert [PDF]
, 2019 Das Marburg Virus (MARV) gehört, wie das Ebola Virus (EBOV), zur Familie der Filoviridae. Im Menschen führt eine Infektion mit dem MARV häufig zu schweren Fiebererkrankungen mit einer Letalitätsrate von bis zu 90%.
Rohde, Cornelius
core +1 more source
Filoviral Immune Evasion Mechanisms
Viruses, 2011 The Filoviridae family of viruses, which includes the genera Ebolavirus (EBOV) and Marburgvirus (MARV), causes severe and often times lethal hemorrhagic fever in humans. Filoviral infections are associated with ineffective innate antiviral responses as a
Christopher F. Basler +5 more
doaj +1 more source
Essentials of Filoviral Load Quantification [PDF]
, 2016 Quantitative measurement of viral load is an important parameter in the management of filovirus disease outbreaks because viral load correlates with severity of disease, survival, and infectivity.
Ariën, KK +18 more
core +1 more source
, 2014 Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 25, Issue 3, Page 128-129, 2014.
Kevin B Laupland, Louis Valiquette
wiley +1 more source
Mechanisms of immunity in post-exposure vaccination against Ebola virus infection. [PDF]
PLoS ONE, 2015 Ebolaviruses can cause severe hemorrhagic fever that is characterized by rapid viral replication, coagulopathy, inflammation, and high lethality rates.
Steven B Bradfute +8 more
doaj +1 more source
Ebola Virus Localization in the Macaque Reproductive Tract during Acute Ebola Virus Disease. [PDF]
, 2018 Sexual transmission of Ebola virus (EBOV) has been demonstrated more than a year after recovery from the acute phase of Ebola virus disease (EVD). The mechanisms underlying EBOV persistence and sexual transmission are not currently understood.
Bernbaum, John G. +7 more
core +1 more source