Development of a model for marburgvirus based on severe-combined immunodeficiency mice [PDF]
Virology Journal, 2007 The filoviruses, Ebola (EBOV) and Marburg (MARV), cause a lethal hemorrhagic fever. Human isolates of MARV are not lethal to immmunocompetent adult mice and, to date, there are no reports of a mouse-adapted MARV model. Previously, a uniformly lethal EBOV-
Kalina Warren V +7 more
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Filovirus RefSeq Entries: Evaluation and Selection of Filovirus Type Variants, Type Sequences, and Names [PDF]
Viruses, 2014 Sequence determination of complete or coding-complete genomes of viruses is becoming common practice for supporting the work of epidemiologists, ecologists, virologists, and taxonomists.
Jens H. Kuhn +75 more
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Discovery of common marburgvirus protective epitopes in a BALB/c mouse model [PDF]
Virology Journal, 2009 Background Marburg virus (MARV) causes acute hemorrhagic fever that is often lethal, and no licensed vaccines are available for preventing this deadly viral infection.
Olinger Gene G +3 more
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Implementation of Objective PASC-Derived Taxon Demarcation Criteria for Official Classification of Filoviruses [PDF]
Viruses, 2017 The mononegaviral family Filoviridae has eight members assigned to three genera and seven species. Until now, genus and species demarcation were based on arbitrarily chosen filovirus genome sequence divergence values (≈50% for genera, ≈30% for species ...
Yīmíng Bào +22 more
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Preliminary Investigation of Schmalhausen’s Law in a Directly Transmitted Pathogen Outbreak System [PDF]
Viruses, 2023 The past few decades have been marked by drastic modifications to the landscape by anthropogenic processes, leading to increased variability in the environment. For populations that thrive at their distributional boundaries, these changes can affect them
Antoine Filion +2 more
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Marburg Virus Disease: A Narrative Review [PDF]
Health Science Reports, Volume 8, Issue 5, May 2025.ABSTRACT Background and Aims Given the recent deadly outbreaks of the Marburg virus (MARV), in early 2023 in Tanzania and Equatorial Guinea, and the most recent one in Rwanda in 2024, there has been renewed attention across Africa on the threat posed by the re‐emergence of MARV as a growing concern for public health.
Arash Letafati +4 more
wiley +2 more sources
Process Intensification for Recombinant Marburg Virus Glycoprotein Production Using Drosophila S2 Cells [PDF]
Engineering in Life Sciences, Volume 25, Issue 5, May 2025.ABSTRACT Marburg marburgvirus (MARV) is a highly virulent human pathogen with limited therapeutic options. Recombinant MARV glycoprotein (GP) produced in Drosophila Schneider 2 (S2) cells has been extensively investigated as potential vaccine antigen with promising efficacy demonstrated in nonhuman primate models.
Sven Göbel +7 more
wiley +2 more sources
Development of a Pan-Filoviridae SYBR Green qPCR Assay for Biosurveillance Studies in Bats [PDF]
Viruses, 2023 Recent studies have indicated that bats are hosts to diverse filoviruses. Currently, no pan-filovirus molecular assays are available that have been evaluated for the detection of all mammalian filoviruses.
Jessica Coertse +5 more
doaj +2 more sources
Identification of Filovirus Entry Inhibitors from Marine Fungus-Derived Indole Alkaloids [PDF]
Marine DrugsFiloviruses, mainly consisting of the two genera of Ebolavirus and Marburgvirus, are enveloped negative-strand RNA viruses that can infect humans to cause severe hemorrhagic fevers and outbreaks with high mortality rates.
Leah Liu Wang +6 more
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Evolutionary maintenance of filovirus-like genes in bat genomes [PDF]
BMC Evolutionary Biology, 2011 Background Little is known of the biological significance and evolutionary maintenance of integrated non-retroviral RNA virus genes in eukaryotic host genomes.
Taylor Derek J +3 more
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