Recent advances in marburgvirus research [version 1; peer review: 3 approved] [PDF]
F1000Research, 2019 Marburgviruses are closely related to ebolaviruses and cause a devastating disease in humans. In 2012, we published a comprehensive review of the first 45 years of research on marburgviruses and the disease they cause, ranging from molecular biology to ...
Judith Olejnik +2 more
doaj +5 more sources
Marburgvirus Hijacks Nrf2-Dependent Pathway by Targeting Nrf2-Negative Regulator Keap1 [PDF]
Cell Reports, 2014 Marburg virus (MARV) has a high fatality rate in humans, causing hemorrhagic fever characterized by massive viral replication and dysregulated inflammation.
Audrey Page +14 more
doaj +5 more sources
Marburgvirus in Egyptian Fruit Bats, Zambia [PDF]
Emerging Infectious Diseases, 2019 We detected Marburg virus genome in Egyptian fruit bats (Rousettus aegyptiacus) captured in Zambia in September 2018. The virus was closely related phylogenetically to the viruses that previously caused Marburg outbreaks in the Democratic Republic of the
Masahiro Kajihara +19 more
doaj +5 more sources
Discovery of common marburgvirus protective epitopes in a BALB/c mouse model [PDF]
Virology Journal, 2009 Background Marburg virus (MARV) causes acute hemorrhagic fever that is often lethal, and no licensed vaccines are available for preventing this deadly viral infection.
Olinger Gene G +3 more
doaj +5 more sources
PLoS Pathogens, 2010 Vertebrate genomes contain numerous copies of retroviral sequences, acquired over the course of evolution. Until recently they were thought to be the only type of RNA viruses to be so represented, because integration of a DNA copy of their genome is ...
Vladimir A Belyi +2 more
doaj +4 more sources
Development of a model for marburgvirus based on severe-combined immunodeficiency mice [PDF]
Virology Journal, 2007 The filoviruses, Ebola (EBOV) and Marburg (MARV), cause a lethal hemorrhagic fever. Human isolates of MARV are not lethal to immmunocompetent adult mice and, to date, there are no reports of a mouse-adapted MARV model. Previously, a uniformly lethal EBOV-
Kalina Warren V +7 more
doaj +5 more sources
Immunoinformatic and reverse vaccinology-based designing of potent multi-epitope vaccine against Marburgvirus targeting the glycoprotein [PDF]
Heliyon, 2023 Marburg virus (MARV) has been a major concern since its first outbreak in 1967. Although the deadly BSL-4 pathogen has been reported in few individuals with sporadic outbreaks following 1967, its rarity commensurate the degree of disease severity.
Hassan Yousaf +6 more
doaj +4 more sources
Budding of Marburgvirus is associated with filopodia [PDF]
Cellular Microbiology, 2006 Viruses exploit the cytoskeleton of host cells to transport their components and spread to neighbouring cells. Here we show that the actin cytoskeleton is involved in the release of Marburgvirus (MARV) particles. We found that peripherally located nucleocapsids and envelope precursors of MARV are located either at the tip or at the side of filopodial ...
Larissa Kolesnikova +3 more
openalex +3 more sources
Experimental Inoculation of Egyptian Rousette Bats (Rousettus aegyptiacus) with Viruses of the Ebolavirus and Marburgvirus Genera [PDF]
Viruses, 2015 The Egyptian rousette bat (Rousettus aegyptiacus) is a natural reservoir for marburgviruses and a consistent source of virus spillover to humans. Cumulative evidence suggests various bat species may also transmit ebolaviruses.
Megan E.B. Jones +6 more
doaj +5 more sources
Marburgvirus Resurgence in Kitaka Mine Bat Population after Extermination Attempts, Uganda [PDF]
Emerging Infectious Diseases, 2014 To the Editor: Marburg virus (MARV) and Ravn virus (RAVV), collectively called marburgviruses, cause Marburg hemorrhagic fever (MHF) in humans. In July 2007, 4 cases of MHF (1 fatal) occurred in miners at Kitaka Mine in southern Uganda. Later, MHF occurred in 2 tourists who visited Python Cave, ≈50 km from Kitaka Mine.
Brian Amman +11 more
doaj +4 more sources