Results 21 to 30 of about 1,452 (166)

Isolation and genome characterization of Lloviu virus from Italian Schreibers’s bats [PDF]

Scientific Reports, 2023
Lloviu cuevavirus (LLOV) was the first identified member of Filoviridae family outside the Ebola and Marburgvirus genera. A massive die-off of Schreibers’s bats (Miniopterus schreibersii) in the Iberian Peninsula in 2002 led to its initial discovery ...
Gábor E. Tóth, Adam J. Hume, Ellen L. Suder, Safia Zeghbib, Ágota Ábrahám, Zsófia Lanszki, Zsaklin Varga, Zsófia Tauber, Fanni Földes, Brigitta Zana, Dino Scaravelli, Maria Teresa Scicluna, Andrea Pereswiet-Soltan, Tamás Görföl, Calogero Terregino, Paola De Benedictis, Isabel Garcia-Dorival, Covadonga Alonso, Ferenc Jakab, Elke Mühlberger, Stefania Leopardi, Gábor Kemenesi   +21 more
doaj   +2 more sources

Marburgvirus [PDF]

, 2020

openalex   +2 more sources

Homo-Oligomerization of Marburgvirus VP35 Is Essential for Its Function in Replication and Transcription [PDF]

Journal of Virology, 2005
ABSTRACT The nucleocapsid protein VP35 of Marburgvirus, a filovirus, acts as the cofactor of the viral polymerase and plays an essential role in transcription and replication of the viral RNA. VP35 forms complexes with the genome encapsidating protein NP and with the RNA-dependent RNA polymerase L.
Peggy Möller, Nonia Pariente, Hans‐Dieter Klenk, Stephan Becker   +3 more
openalex   +5 more sources

Ebolavirus and Marburgvirus: Insight the Filoviridae family [PDF]

Molecular Aspects of Medicine, 2007
Ebolavirus and Marburgvirus (belonging to the Filoviridae family) emerged four decades ago and cause epidemics of haemorrhagic fever with high case-fatality rates. The genome of filoviruses encodes seven proteins. No significant homology is observed between filovirus proteins and any known macromolecule.
Paolo Ascenzi, Alessio Bocedi, J Heptonstall, Maria Rosaria Capobianchi, Antonino Di, Eloise Mastrangelo, Martino Bolognesi, Giuseppe Ippolito   +7 more
openalex   +11 more sources

Marburg Virus Disease: A Narrative Review. [PDF]

Health Sci Rep
ABSTRACT Background and Aims Given the recent deadly outbreaks of the Marburg virus (MARV), in early 2023 in Tanzania and Equatorial Guinea, and the most recent one in Rwanda in 2024, there has been renewed attention across Africa on the threat posed by the re‐emergence of MARV as a growing concern for public health.
Letafati A, Fakhr SSH, Najafabadi AQ, Karami N, Karami H.   +4 more
europepmc   +2 more sources

Ebolavirus Δ-Peptide Immunoadhesins Inhibit Marburgvirus and Ebolavirus Cell Entry [PDF]

Journal of Virology, 2011
ABSTRACT With the exception of Reston and Lloviu viruses, filoviruses (marburgviruses, ebolaviruses, and “cuevaviruses”) cause severe viral hemorrhagic fevers in humans. Filoviruses use a class I fusion protein, GP 1,2 , to bind to an unknown, but shared, cell surface receptor to initiate virus-cell fusion.
Sheli R. Radoshitzky, Kelly L. Warfield, Xiǎolì Chī, Lián Dŏng, Krishna P. Kota, Steven B. Bradfute, Jacqueline Gearhart, Cary Retterer, Philip J. Kranzusch, John Misasi, Marc A. Hogenbirk, Victoria Wahl‐Jensen, Viktor E. Volchkov, James M. Cunningham, Peter B. Jahrling, M. Javad Aman, Sina Bavari, Michael Farzan, Jens H. Kuhn   +18 more
openalex   +5 more sources

Vaccinomics strategy for developing a unique multi-epitope monovalent vaccine against Marburg marburgvirus [PDF]

Infection, Genetics and Evolution, 2018
Marburg virus causes severe hemorrhagic fever in both humans and non-human primates with high degree of infectivity and lethality. To date no approved treatment is available for Marburg virus infection. A study was employed to design a novel chimeric vaccine against Marburg virus by adopting reverse vaccinology approach.
Mahmudul Hasan, Kazi Faizul Azim, Aklima Begum, Noushin Anika Khan, Tasfia Saiyara Shammi, Md. Abdus Shukur Imran, Ishtiak Malique Chowdhury, Shah Rucksana Akhter Urme   +7 more
  +6 more sources

Marburgvirus Nucleoprotein-Capture Enzyme-Linked Immunosorbent Assay Using Monoclonal Antibodies to Recombinant Nucleoprotein: Detection of Authentic Marburgvirus

Japanese Journal of Infectious Diseases, 2006
There have recently been large outbreaks of Marburg hemorrhagic fever (MHF) caused by Marburgvirus (MARV) in the Democratic Republic of Congo and Angola. The development of reliable diagnostic systems for MHF is urgently needed. An antigen-capture enzyme-linked immunosorbent assay (Ag-capture ELISA) using either of the two monoclonal antibodies (2A7 ...
Masayuki Saijo, Marie‐Claude Georges‐Courbot, Shuetsu Fukushi, Tetsuya Mizutani, Marianneau Philippe, Alain‐Jean Georges, Ichiro Kurane, Shigeru Morikawa   +7 more
openalex   +4 more sources

Process Intensification for Recombinant Marburg Virus Glycoprotein Production Using <i>Drosophila</i> S2 Cells. [PDF]

Eng Life Sci
ABSTRACT Marburg marburgvirus (MARV) is a highly virulent human pathogen with limited therapeutic options. Recombinant MARV glycoprotein (GP) produced in Drosophila Schneider 2 (S2) cells has been extensively investigated as potential vaccine antigen with promising efficacy demonstrated in nonhuman primate models.
Göbel S, Mayerlen L, Eiser IY, Fichtmueller L, Clements D, Reichl U, Genzel Y, Lehrer A.   +7 more
europepmc   +2 more sources

Immunoinformatic screening of Marburgvirus epitopes and computational investigations of epitope-allele complexes

SSRN Electronic Journal, 2022
Marburgvirus (MARV), a member of the Filovirus family, causes severe hemorrhagic fever in humans. Currently, there are no approved vaccines or post exposure treatment methods available against MARV. With the aim of identifying vaccine candidates against MARV, we employ different sequence-based computational methods to predict the MHC-I and MHC-II T ...
Prabin Baral, Elumalai Pavadai, Ziyou Zhou, Yang Xu, Christopher K. Tison, Rudramani Pokhrel, Bernard S. Gerstman, Prem P. Chapagain   +7 more
openalex   +4 more sources