Results 41 to 50 of about 2,702 (198)

Untersuchungen zur Rolle des VP24 im Vermehrungszyklus des Marburgvirus

, 2005
The highly pathogenic enveloped Marburgvirus (MARV) is composed of seven structural proteins and the nonsegmented negative-sensed viral RNA genome. Four proteins (NP, VP35, VP30, and L) make up the helical nucleocapsid complex which is surrounded by a matrix that is composed of VP40 and VP24.
Sandra Bamberg
openalex   +4 more sources

Conserved Receptor-binding Domains of Lake Victoria Marburgvirus and Zaire Ebolavirus Bind a Common Receptor [PDF]

Journal of Biological Chemistry, 2006
The GP(1,2) envelope glycoproteins (GP) of filoviruses (marburg- and ebolaviruses) mediate cell-surface attachment, membrane fusion, and entry into permissive cells. Here we show that a 151-amino acid fragment of the Lake Victoria marburgvirus GP1 subunit bound filovirus-permissive cell lines more efficiently than full-length GP1.
Jens H. Kuhn, Sheli R. Radoshitzky, Alexander C. Guth, Kelly L. Warfield, Wenhui Li, Martin J. Vincent, Jonathan S. Towner, Stuart T. Nichol, Sina Bavari, Hyeryun Choe, M. Javad Aman, Michael Farzan   +11 more
openalex   +4 more sources

Phosphorylation of Marburgvirus NP and its influence on the viral life cycle

, 2016
Das Marburgvirus (MARV) bildet zusammen mit Ebolavirus (EBOV) und Lloviuvirus (LLOV) die Familie der Filoviridae und besitzt ein einzelsträngiges RNA-Genom negativer Orientierung. Filoviren werden als BSL-4-Pathogene klassifiziert, da sie schwere hämorrhagische Fieber bei Menschen und Affen verursachen. Das Nukleoprotein
Anne Kelterbaum
openalex   +2 more sources

Unveiling a drift-resistant cryptotope within Marburgvirus nucleoprotein recognized by llama single-domain antibodies [PDF]

Acta Crystallographica Section A Foundations and Advances, 2018
(Uploaded by Plazi for the Bat Literature Project) Marburg virus (MARV) is a highly lethal hemorrhagic fever virus that is increasingly re-emerging in Africa, has been imported to both Europe and the US, and is also a Tier 1 bioterror threat. As a negative sense RNA virus, MARV has error prone replication which can yield progeny capable of evading ...
Alex Taylor, J.A. Garza, Laura J. Sherwood, John Hart, Andrew Hayhurst   +4 more
openalex   +5 more sources

Marburg Virus Disease: A Narrative Review. [PDF]

Health Sci Rep
ABSTRACT Background and Aims Given the recent deadly outbreaks of the Marburg virus (MARV), in early 2023 in Tanzania and Equatorial Guinea, and the most recent one in Rwanda in 2024, there has been renewed attention across Africa on the threat posed by the re‐emergence of MARV as a growing concern for public health.
Letafati A, Fakhr SSH, Najafabadi AQ, Karami N, Karami H.   +4 more
europepmc   +2 more sources

Process Intensification for Recombinant Marburg Virus Glycoprotein Production Using <i>Drosophila</i> S2 Cells. [PDF]

Eng Life Sci
ABSTRACT Marburg marburgvirus (MARV) is a highly virulent human pathogen with limited therapeutic options. Recombinant MARV glycoprotein (GP) produced in Drosophila Schneider 2 (S2) cells has been extensively investigated as potential vaccine antigen with promising efficacy demonstrated in nonhuman primate models.
Göbel S, Mayerlen L, Eiser IY, Fichtmueller L, Clements D, Reichl U, Genzel Y, Lehrer A.   +7 more
europepmc   +2 more sources

Structural and biochemical characterization of marburgvirus VP35 and its role in immune evasion

, 2012
Parameshwaran Ramanan
openalex   +4 more sources

Serological Evidence of Filovirus Infection in Nonhuman Primates in Zambia

Viruses, 2021
Ebolaviruses and marburgviruses are filoviruses that are known to cause severe hemorrhagic fever in humans and nonhuman primates (NHPs). While some bat species are suspected to be natural reservoirs of these filoviruses, wild NHPs often act as ...
Katendi Changula, Edgar Simulundu, Boniface Pongombo Lombe, Eri Nakayama, Hiroko Miyamoto, Yuji Takahashi, Hirofumi Sawa, Chuma Simukonda, Bernard M. Hang’ombe, Ayato Takada   +9 more
doaj   +1 more source

Communicating the risks of handling bats: analysing approaches used by Australian stakeholders in the context of Australian bat lyssavirus

Australian Veterinary Journal, Volume 101, Issue 11, Page 430-439, November 2023., 2023
Australian bat lyssavirus (ABLV) is a member of the Lyssavirus genus of the Rhabdoviridae family and is found in Australian bat species. It is of public health concern because of the rabies‐like syndrome it causes in humans, resulting in government health and wildlife agencies using varied communication approaches to inform targeted audiences about ...
BP Liang, K Wingett, KL Bosward, MR Taylor   +3 more
wiley   +1 more source

First‐ever Marburg virus disease outbreak in Equatorial Guinea and Tanzania: An imminent crisis in West and East Africa

Immunity, Inflammation and Disease, Volume 11, Issue 8, August 2023., 2023
The Marburg virus causes the severe infectious disease known as Marburg Virus Disease (MVD). Previously, different outbreaks of MVD have appeared in different African countries. For the first time, Equatorial Guinea and Tanzania are experiencing MVD outbreaks.
Olivier Sibomana, Emmanuel Kubwimana
wiley   +1 more source