Results 61 to 70 of about 2,702 (198)

Ebola virus VP30 and nucleoprotein interactions modulate viral RNA synthesis [PDF]

, 2017
Ebola virus (EBOV) is an enveloped negative-sense RNA virus that causes sporadic outbreaks with high case fatality rates. Ebola viral protein 30 (eVP30) plays a critical role in EBOV transcription initiation at the nucleoprotein (eNP) gene, with ...
Amarasinghe, Gaya K, Basler, Christopher F, Batra, Jyoti, Leung, Daisy W, Luthra, Priya, Wu, Chao, Xu, Wei   +6 more
core   +2 more sources

Virulence of Marburg Virus Angola Compared to Mt. Elgon (Musoke) in Macaques: A Pooled Survival Analysis

Viruses, 2018
Angola variant (MARV/Ang) has replaced Mt. Elgon variant Musoke isolate (MARV/MtE-Mus) as the consensus standard variant for Marburg virus research and is regarded as causing a more aggressive phenotype of disease in animal models; however, there is a ...
Paul W. Blair, Maryam Keshtkar-Jahromi, Kevin J. Psoter, Ronald B. Reisler, Travis K. Warren, Sara C. Johnston, Arthur J. Goff, Lydia G. Downey, Sina Bavari, Anthony P. Cardile   +9 more
doaj   +1 more source

Treatment of Marburg and Ebola hemorrhagic fevers: A strategy for testing new drugs and vaccines under outbreak conditions. [PDF]

, 2008
The filoviruses, Marburg and Ebola, have the dubious distinction of being associated with some of the highest case-fatality rates of any known infectious disease-approaching 90% in many outbreaks.
A.G. Sprecher, Anon., Baize, Basler, Bausch, Bausch, Bausch, Bausch, Bausch, Bausch, Bausch, Bausch, Benjamin Jeffs, Bernard, Borchert, Bosio, Bosio, Boumandouki, Bray, Bray, Bray, Bray, Brummel-Ziedins, Bukreyev, Bwaka, CDC and WHO, Colebunders, Daddario-DiCaprio, Daniel G. Bausch, Dowell, Egbring, Emond, Enterlein, Feldmann, Formenty, Fourrier, Gear, Geisbert, Geisbert, Geisbert, Geisbert, Geisbert, Geisbert, Geisbert, Geisbert, Gibbs, Gupta, Hensley, Hensley, Hensley, Hewlett, Hewlett, Hoenen, Hotchkiss, Huggins, Jahrling, Jahrling, Jahrling, Jeffs, Johnson, Jones, Jones, Khan, Ksiazek, Kudoyarova-Zubavichene, Larkin, Leroy, Leroy, Mahanty, Mahanty, Martin, Martini, Martini, Monath, Mupapa, Mupapa, Nikiforov, Oswald, Parrino, Pattyn, Paul Boumandouki, Peters, Peterson, Peterson, Pourrut, Reid, Rivers, Roberts, Rollin, Sanchez, Schnittler, Schuler, Smith, Spurgers, Stille, Sullivan, Sullivan, Swanepoel, Takada, Todorovitch, Towner, Warfield, Warfield, Warfield, Wilson, Zaki   +105 more
core   +2 more sources

Assessing the feasibility of Phase 3 vaccine trials against Marburg Virus Disease: A modelling study

Vaccine: X, 2023
Background: Outbreaks of Marburg virus disease (MVD) are rare and small in size, with only 18 recorded outbreaks since 1967, only two of which involved more than 100 cases.
George Y. Qian, Thibaut Jombart, W. John Edmunds   +2 more
doaj   +1 more source

Mapping the zoonotic niche of Marburg virus disease in Africa. [PDF]

, 2015
BACKGROUND: Marburg virus disease (MVD) describes a viral haemorrhagic fever responsible for a number of outbreaks across eastern and southern Africa. It is a zoonotic disease, with the Egyptian rousette (Rousettus aegyptiacus) identified as a reservoir ...
Brady, Oliver J, Golding, Nick, Hay, Simon I, Huang, Zhi, Kraemer, Moritz UG, Mylne, Adrian, Pigott, David M, Weiss, Daniel J   +7 more
core   +2 more sources

Recent outbreak of Marburg virus disease: Could it be a threat for global public health?

, 2023
Health Science Reports, Volume 6, Issue 1, January 2023.
Md. Sohan, Mohammad Shahriar, Mohiuddin Ahmed Bhuiyan, Md. Rabiul Islam   +3 more
wiley   +1 more source

Filovirus Entry: A Novelty in the Viral Fusion World

Viruses, 2012
Ebolavirus (EBOV) and Marburgvirus (MARV) that compose the filovirus family of negative strand RNA viruses infect a broad range of mammalian cells.
Wendy Maury, Catherine L. Hunt, Nicholas J. Lennemann   +2 more
doaj   +1 more source

Panmicrobial oligonucleotide array for diagnosis of infectious diseases [PDF]

, 2007
To facilitate rapid, unbiased, differential diagnosis of infectious diseases, we designed GreeneChipPm, a panmicrobial microarray comprising 29,455 sixty-mer oligonucleotide probes for vertebrate viruses, bacteria, fungi, and parasites.
Briese, Thomas, Büchen-Osmond, Cornelia, Conlan, Sean, Ellerbrok, Heinz, Feldmann, Heinz, Formenty, Pierre, Geisbert, Thomas W., Grolla, Allen, Hegyi, Hedi, Hirschberg, David L., Hui, Jeffrey, Jabado, Omar J., Jahrling, Peter B., Lipkin, W. Ian, Liu, Yang, Lussier, Yves, Nichol, Stuart T., Palacios, Gustavo F., Quan, Phuong-Lan, Renwick, Neil, Sanchez-Seco, Maria Paz, Strong, James E., Towner, Jonathan S., Zhai, Junhui   +23 more
core   +3 more sources

Outbreak of Marburg hemorrhagic fever among miners in Kamwenge and Ibanda Districts, Uganda, 2007 [PDF]

, 2011
Marburg hemorrhagic fever was detected among 4 miners in Ibanda District, Uganda, from June through September, 2007. Infection was likely acquired through exposure to bats or bat secretions in a mine in Kamwenge District, Uganda, and possibly human-to ...
Atek Kagirita, Bausch, Bausch, Ben Jeffs, Brian Amman, Centers for Disease Control and Prevention, Centers for Disease Control and Prevention, Craig Manning, Edgar Kansiime, Eileen C. Farnon, Emmanuel Byaruhanga, F. Katunguka, Florimond Tschioko, Godfrey S. Bwire, Jennifer Adjemian, Jentes, Jonathan Towner, Jordan W. Tappero, Joseph F. Wamala, Julius J. Lutwama, Pierre E. Rollin, Pierre Formenty, Robert Downing, Sam Ahimbisibwe, Stuart T. Nichol, Swanepoel, Taylor, Timen, Towner, Towner, Wahl-Jensen, World Health Organization   +31 more
core   +2 more sources

A Call to Action to Enhance Filovirus Disease Outbreak Preparedness and Response

Viruses, 2014
The frequency and magnitude of recognized and declared filovirus-disease outbreaks have increased in recent years, while pathogenic filoviruses are potentially ubiquitous throughout sub-Saharan Africa.
Paul Roddy
doaj   +1 more source