Results 101 to 110 of about 209 (125)
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Total Synthesis and Bioactivities of Two Proposed Structures of Maresin
Chemistry – An Asian Journal, 2010AbstractMaresin is a potent anti‐inflammatory lipid mediator derived from docosahexaenoic acid (DHA). A highly convergent total synthesis of two proposed structures of C7‐epimeric maresins from the four known fragments was achieved in 17 steps. The three key coupling reactions were the BF3‐mediated alkyne attack on the epoxide, chiral titanium complex ...
Kenji, Sasaki +4 more
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Serum Maresin 1 levels in idiopathic acute anterior uveitis patients
Journal Français d'Ophtalmologie, 2022The purpose of the present study is to assess the levels of Maresin 1 (MaR1) in patients with idiopathic acute anterior uveitis (IAAU) and to compare the MaR1 results with healthy controls.This study includes 24 patients with idiopathic AAU and 24 healty controls (C). The serum MaR1 levels were analyzed using enzyme-linked immunosorbent assays (ELISA).
F.C. Gül +4 more
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Identification of Metabolites of Maresin 1 in Human Neutrophils
The FASEB Journal, 2017The resolution of inflammation, once considered to be rather passive, is now understood to be a complex, regulated process. One of the components in this process is the action of pro‐resolving lipid mediators, including lipoxins, resolvins, protectins and maresins.
Miguel A Gijón +4 more
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Maresin 1 Maintains the Permeability of Lung Epithelial Cells In Vitro and In Vivo
Inflammation, 2016Previous reports showed that Maresin 1 (MaR1) possessed organ protection effects and could attenuate acute lung injury. Here, we aim to figure out whether MaR1 can maintain the permeability of lung epithelial cells by regulating the expression of tight junction protein during lung injury.
Lin, Chen +7 more
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Are decreased serum Maresin 1 levels predictive of cholangiocarcinoma?
Journal of Current Hematology & Oncology ResearchAims: Cholangiocarcinoma (CC) is a rare form of adenocarcinoma originating from the epithelial cells of the biliary tract. Chronic inflammation is known to be a risk factor for this tumor. The present study aimed to investigate whether serum levels of Maresin 1 (MaR1) (a macrophage-derived anti-inflammatory lipid mediator) were associated with the ...
Salih Karatlı +4 more
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Upregulation of the maresin pathway and PGE2 metabolism in the failing human left ventricle
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of LipidsChronic inflammation is involved in the pathogenesis of heart failure (HF), with cardiac remodeling and fibrosis resulting from sustained myofibroblasts activation. This is due to an imbalance between pro-inflammatory and pro-resolving mediators including specialized pro-resolving lipid mediators (SPM).
Amel, Bouhadoun +17 more
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Maresin 1 activates brown adipocytes metabolism
2018Brown adipose tissue (BAT) is the main site for adaptive heat production through non-shivering thermogenesis. BAT has been brought to attention, since it provides a protective mechanism against excessive body weight and fat mass accumulation. Recently, it has been suggested emerging roles of BAT activation in the regulation of metabolism, including ...
Laiglesia, Laura M. +3 more
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Maresin-1 and its receptors RORα/LGR6 as potential therapeutic target for respiratory diseases
Pharmacological Research, 2022Jun Wan, Jishou Zhang
exaly