Results 101 to 110 of about 2,016 (189)

Maresin 1 promotes inflammatory resolution, neuroprotection, and functional neurological recovery after Spinal Cord Injury [PDF]

, 2017
Resolution of inflammation is defective after spinal cord injury (SCI), which impairs tissue integrity and remodeling and leads to functional deficits. Effective pharmacological treatments for SCI are not currently available. Maresin 1 (MaR1) is a highly
Gronert, Karsten, Schwab, Jan M., López Vales, Rubén, Marcel A. Kopp, Brommer, Benedikt, Aaron B. Sullivan, Ruben López-Vales, Sullivan, Aaron B., Jan M. Schwab, David, Samuel, Kopp, Marcel A., Santos Nogueira, Eva, Karsten Gronert, Francos Quijorna, Isaac, Eva Santos-Nogueira, Samuel David, Benedikt Brommer, Isaac Francos-Quijorna   +17 more
core   +1 more source

The future of periodontology: Emerging technologies and conceptual shifts

Journal of Periodontology, Volume 97, Issue 5, Page 875-882, May 2026.
Abstract Periodontology is entering a transformative era driven by advances in diagnostics, therapeutics, and digital integration. Emerging technologies and conceptual shifts are currently reshaping the specialty, with a focus on predictive, preventive, and personalized care.
Michael S. Reddy
wiley   +1 more source

Maresin conjugates in tissue regeneration biosynthesis enzymes in human macrophages

, 2019
Macrophages are central in coordinating immune responses, tissue repair, and regeneration, with different subtypes being associated with inflammation-initiating and proresolving actions.
Chiang, Nan, Dalli, Jesmond, Spur, Bernd, Rodriguez, Ana, Serhan, Charles, Petasis, Nicos, Riley, Ian, Vlasakov, Iliyan   +7 more
core   +1 more source

Eicosapentaenoic and Docosahexaenoic Acid Levels in Mouse Tissues After Intake of Echium and Ahiflower Oils Rich in Stearidonic and α‐Linolenic Acids

Lipids, Volume 61, Issue 3, Page 417-426, May 2026.
Dietary supplementation with stearidonic acid–rich Echium and Ahiflower oils increases EPA levels across multiple mouse tissues, while DHA responses remain tissue‐specific and limited, supporting the strategic use of plant‐based omega‐3 sources for EPA‐focused interventions. ABSTRACT Omega‐3 fatty acids (n‐3 FA), particularly eicosapentaenoic acid (EPA)
Letícia V. Segre, Mariana S. Bisinotto, Inar A. Castro   +2 more
wiley   +1 more source

Maresin 1 Biosynthesis and Proresolving Anti-infective Functions with Human-Localized Aggressive Periodontitis Leukocytes

, 2019
Localized aggressive periodontitis (LAP) is a distinct form of early-onset periodontitis linked to periodontal infection with uncontrolled inflammation and leukocyte-mediated tissue destruction.
Chiang, Nan, Dalli, Jesmond, Arnardottir, Hildur, Serhan, Charles, Colas, Romain, Hasturk, Hatice, Van Dyke, Thomas E., Wang, Chin-Wei, Nguyen, Daniel   +8 more
core   +1 more source

Maresin-like 1 Ameliorates Neuropathology of Alzheimer's Disease in Brains of a Transgenic Mouse Model. [PDF]

Biomedicines
(1) Background: Impeded resolution of inflammation contributes substantially to the pathogenesis of Alzheimer’s disease (AD); consequently, resolving inflammation is pivotal to the amelioration of AD pathology.
Shrivastava P, Lu Y, Su S, Kobayashi Y, Zhao Y, Lien N, Masoud AR, Lukiw WJ, Hong S.   +8 more
europepmc   +2 more sources

Protectin D1 and maresin 1 attenuate airway hyperreactivity induced by IL‐13 in human isolated small bronchi

British Journal of Pharmacology, Volume 183, Issue 9, Page 2049-2060, May 2026.
Background and Purpose Interleukin (IL)‐13 is implicated in airway hyperreactivity (AHR), a key feature of asthma. We explored the potential anti‐AHR activity of selected specialised pro‐resolving mediators (SPMs) in IL‐13‐induced AHR models, using human bronchial smooth muscle cells (BSMCs) and human isolated bronchi.
Willem Abma, Sven‐Erik Dahlén, Craig E. Wheelock, Mikael Adner, Mamdoh Al‐Amerie, Erik Sachs, Kasra Vali Jalali, Leonardo De Maria, Henric Olsson, Jesper Säfholm   +9 more
wiley   +1 more source

Resolvin D5 Inhibits CXCL8 Expression in Colonic Epithelial Cells Through Activating GPR101 to Impede Neutrophil Recruitment and Consequently Alleviate Ulcerative Colitis

Advanced Science, Volume 13, Issue 21, 13 April 2026.
RvD5 effectively alleviates UC by inhibiting STAT1 signaling to reduce CXCL8 expression in colonic epithelial cells via activation of GPR101, which subsequently decreases the infiltration of neutrophils in the colonic mucosal epithelium. Epimedin A1, a natural allosteric inhibitor of 5‐LOX, demonstrates potential as a therapeutic agent for UC by ...
Pengxiang Guo, Yilei Guo, Yanrong Zhu, Ke Yan, Yulai Fang, Jiafeng Zhang, Yue He, Zhifeng Wei, Yufeng Xia, Yue Dai   +9 more
wiley   +1 more source

Effects of Maresin 1 (MaR1) on Colonic Inflammation and Gut Dysbiosis in Diet-Induced Obese Mice

, 2020
The aim of this study was to characterize the effects of Maresin 1 (MaR1), a DHA-derived pro-resolving lipid mediator, on obesity-related colonic inflammation and gut dysbiosis in diet-induced obese (DIO) mice.
Escoté-Miró, X. (Xavier), Moreno-Aliaga, M. J. (María Jesús), Sainz, N. (Neira), Guruceaga, E. (Elizabeth), Vázquez, S. (Sergio), León, I.C. (Irene C.)   +5 more
core   +3 more sources

Maresin 1 Attenuates Radicular Pain Through the Inhibition of NLRP3 Inflammasome-Induced Pyroptosis via NF-κB Signaling

Frontiers in Neuroscience, 2020
BackgroundThe exposure of the nucleus pulposus (NP) causes an immune and inflammatory response, which is intrinsically linked to the pathogenesis of radicular pain. As a newly discovered pro-resolving lipid mediator, maresin 1 (MaR1) could exert powerful
Yi-hao Wang, Yi-hao Wang, Yan Li, Jun-nan Wang, Qing-xiang Zhao, Jin Jin, Shuang Wen, Si-cong Wang, Tao Sun   +8 more
doaj   +1 more source