Results 91 to 100 of about 2,016 (189)

Maresin: Macrophage Mediator for Resolving Inflammation and Bridging Tissue Regeneration—A System-Based Preclinical Systematic Review

, 2023
Maresins are lipid mediators derived from omega-3 fatty acids with anti-inflammatory and pro-resolving properties, capable of promoting tissue regeneration and potentially serving as a therapeutic agent for chronic inflammatory diseases.
Wei-Ming Chang, Chin-Wei Wang, Yu-Hsin Yang, Wen-Chun Liu, Yu-Chin Wang   +4 more
core   +1 more source

Differential Effects of Benralizumab and Mepolizumab on Pro‐Resolving Mediators

Allergy, EarlyView.
Jaime Bernaola, José Antonio Cañas, Álvaro Arranz‐Fragua, José Manuel Rodrigo‐Muñoz, Daniel Rodríguez‐González, Antonio Serrano‐Santiago, Gema Guillén‐Sánchez, Alma Martínez Fernández, Marcela Valverde‐Monge, Diana Betancor, Erwin Javier Pinillos‐Robles, Claudia Rodríguez‐Busto, María Jesús Rodríguez‐Nieto, Joaquín Sastre, Victoria del Pozo   +14 more
wiley   +1 more source

Fatty Acid Metabolism in Health and Cancer: From Fundamental Mechanisms to Therapeutic Application

MedComm, Volume 7, Issue 6, June 2026.
The modulation of the TME by fatty acid metabolism primarily occurs through four key pathways: inflammation regulation, signal transduction, translation to TME, and oxidative stress. ABSTRACT Fatty acid metabolism (FAM) plays a vital role in maintaining health by supporting energy production, cellular structure, and signaling processes.
Na Hang, Runkang Zhao, Fan Zhang, Dandan Guo, Qing Li, Zhijun Shen, Ruiqing Gao, Chenyu Gao, Zhao Xie, Sentao Fu, Peng Luo, Bufu Tang, Ling Wang   +12 more
wiley   +1 more source

Maresin 1 biosynthesis during platelet–neutrophil interactions is organ-protective [PDF]

Proceedings of the National Academy of Sciences, 2014
Significance Neutrophil accumulation is fundamental to acute inflammation. In response to tissue injury, circulating neutrophil–platelet aggregates (N-PAs) form for secondary capture. Counterregulation of acute inflammatory processes by specialized proresolving mediators is essential to mitigate collateral injury to healthy bystander tissue ...
Abdulnour, Raja-Elie, Dalli, Jesmond, Colby, Jennifer, Krishnamoorthy, Nandini, Timmons, Jack, Tan, Sook Hwa, Colas, Romain, Petasis, Nicos, Serhan, Charles, Levy, Bruce   +9 more
openaire   +4 more sources

Maresin 1 biosynthesis during platelet–neutrophil interactions is organ-protective

, 2019
Unregulated acute inflammation can lead to collateral tissue injury in vital organs, such as the lung during the acute respiratory distress syndrome.
Dalli, Jesmond, Colby, Jennifer, Abdulnour, Raja-Elie, Timmons, Jack, Serhan, Charles, Colas, Romain, Petasis, Nicos, Krishnamoorthy, Nandini, Levy, Bruce, Tan, Sook Hwa   +9 more
core   +1 more source

The specialized pro-resolving lipid mediator maresin 1 protects hepatocytes from lipotoxic and hypoxia-induced endoplasmic reticulum stress. [PDF]

, 2019
Endoplasmic reticulum (ER) stress and activation of the unfolded protein response (UPR) are hallmarks of nonalcoholic fatty liver disease (NAFLD), which is the hepatic manifestation of the metabolic syndrome associated with obesity.
Rius, Bibiana, Titos Rodríguez, Esther, López Vicario, Cristina, Casulleras, Mireia, Duran Güell, Marta, Alcaraz-Quiles, José, Lopategi, Aritz, Lozano Salvatella, Juan José, Flores Costa, Roger, Clària i Enrich, Joan   +9 more
core   +1 more source

The role of presepsin and Maresin-1 levels in blood and synovial fluid in early diagnosis of septic arthritis

Acta Orthopaedica et Traumatologica Turcica
Objective: Early and accurate diagnosis of septic arthritis is essential to prevent irreversible joint damage and systemic complications. This study aimed to evaluate the diagnostic performance of serum and synovial fluid presepsin and Maresin-1 levels ...
Ceren Aydın, Ayşe Sağmak Tartar, Oğuz Aydın, Muhammed Kazez   +3 more
doaj   +1 more source

Endogenous Ceramide 24:1 Constrains Th17‐Driven Neutrophilic Inflammation by Antagonizing EP2 Signaling

Advanced Science, Volume 13, Issue 29, 22 May 2026.
Cer24:1 levels are reduced in neutrophilic asthma and inversely correlate with disease severity and airway neutrophilia. Restoring Cer24:1 suppresses pathogenic Th17 differentiation by engaging EP2 on CD4+ T cells, thereby dampening the JAK2–STAT3–RORγt axis and reducing IL‐17 production.
Huan Liu, Abudureyimujiang Aili, Zheng Kuang, Liting Cao, Zemin Li, Ying Shang, Yingying Ge, Tingting Hu, Yongchang Sun, Wuli Zhao, Rong Jin, Chun Chang   +11 more
wiley   +1 more source

Lipoxin A4 and Resolvin D1 Preserve Neural Inductive Capacity of Dental Pulp Stem Cells Cultured Under Inflammatory Conditions

Cell Biology International, Volume 50, Issue 5, May 2026.
ABSTRACT Human dental pulp stem cells (DPSCs) exhibit neurogenic differentiation potential; however, inflammatory conditions may impair this process. This study investigated the impact of tumor necrosis factor alpha (TNF‐α) on the neurodifferentiation potential of DPSCs and the modulatory role of the pro‐resolving lipid mediators lipoxin A4 (LXA4) and ...
Ana Paula Turrioni, Geovana Pires da Silva, Yan Xu, Alpdogan Kantarci, Hatice Hasturk, Ricardo A. Battaglino, Leslie R. Morse   +6 more
wiley   +1 more source

The relationship between hepatocellular carcinoma and maresin 1

, 2021
Tıp Fakültesi, İç Hastalıkları Ana Bilim DalıGiriş ve Amaç: Karaciğer kanseri, kansere bağlı ölümlerde 4. sıradadır ve hepatoselüler karsinom (HCC), karaciğerin en sık görülen primer malign tümörüdür.
Yücel, Ayşe
core