Results 81 to 90 of about 209 (125)

Maresin 1 Resolves Inflammation and Aids Bone Healing in Periapical Lesions

Journal of Dental Research
Chronic apical periodontitis (CAP) is a persistent inflammatory condition caused by microbial infections in the root canal system, leading to bone loss and tissue damage. In this study, we tested the hypothesis that maresin 1 (MaR1), a specialized proresolving mediator, facilitates inflammatory resolution and promotes bone healing ...
E. Demir, I. İlgenli, Z. Guney, S. Mohammadi, K. Lauwens, N. Yakar, C. Alvarez Rivas, O. Unlu, A. Kantarci   +8 more
openaire   +3 more sources

Maresin 1 induces resolution of hepatic fibrosis through RORα-dependent reprogramming of resident macrophages

Frontiers in Pharmacology
Hepatic fibrosis is a progressive pathological condition characterized by chronic inflammation and excessive extracellular matrix deposition (ECM), which may progress to cirrhosis and liver failure. Although specialized pro-resolving lipid mediators have
Francisca Herrera Vielma, Francisca Herrera Vielma, Matías Quiñones San Martin, Matías Quiñones San Martin, Nicolás Muñoz-Carrasco, Nicolás Muñoz-Carrasco, Fernanda Berrocal-Navarrete, Fernanda Berrocal-Navarrete, Andrés A. Herrada, Alexandra Olate-Briones, Sebastián Zagmutt, Rosalía Rodríguez-Rodríguez, Daniel R. González, Jessica Zúñiga-Hernandez   +13 more
doaj   +1 more source

Maresin 1 modulates renal and cardiac lipid profiles in hypertensive rats

American Journal of Physiology-Renal Physiology
This study shows that MaR1, a specialized proresolving mediator, influences lipid metabolism and modifies gene expression in the heart and kidney in a salt-sensitive hypertension model, without affecting blood pressure or organ structure. These findings highlight the potential role of MaR1 in regulating inflammation and circadian rhythms associated ...
Ruslan Bohovyk, Olha Kravtsova, Gunjan Upadhyay, Vladislav Levchenko, Melissa Lowe, Abigail Shapiro, Ganesh V. Halade, Alexander Staruschenko   +7 more
openaire   +2 more sources

Maresins as novel anti-inflammatory actors and putative therapeutic targets in sepsis

Pharmacological Research
Sepsis, a complex clinical syndrome characterized by an exaggerated host response to infection, often necessitates hospitalization and intensive care unit admission. Delayed or inaccurate diagnosis of sepsis, coupled with suboptimal treatment strategies, can result in unfavorable outcomes, including mortality.
Yan Sun, Shujun Sun, Pu Chen, Yan Dai, Dong Yang, Yun Lin, Lisha Yi   +6 more
openaire   +3 more sources

Circulating Maresin-1 and cartilage remodeling biomarkers in rheumatoid arthritis and osteoarthritis

Scientific Reports
Rheumatoid arthritis (RA) and osteoarthritis (OA) are prevalent chronic joint diseases characterized by persistent inflammation, progressive cartilage degeneration, and impaired tissue repair mechanisms.
Omer Esmez, Gulnihal Deniz, Zubeyde Ercan, Secil Yılmaz, Meryem Sedef Dogru, Ahmet Karatas   +5 more
doaj   +1 more source

Maresin 1 (MaR1) [PDF]

Science-Business eXchange, 2014
openaire   +1 more source

Synthesis of maresin 1 and (7S)-isomer

Synthesis of maresin 1 and (7S)-isomer
identifier:oai:t2r2.star.titech.ac.jp ...
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Pro-resolving mediator maresin 1 ameliorates pain hypersensitivity in a rat spinal nerve ligation model of neuropathic pain

Journal of Pain Research, 2018
Jie Gao,1,2,* Chaoliang Tang,3,4,* Lydia Wai Tai,5 Yeling Ouyang,2,6 Na Li,2,6 Zhiqiang Hu,2,6 Xiangdong Chen2,6 1Department of Anesthesiology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, Anhui Provence, China; 2Department ...
Gao J, Tang C, Tai LW, Ouyang Y, Li N, Hu Z, Chen X   +6 more
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Maresin 1 Alleviates Seizure Symptoms by Modulating the Crosstalk Between Inflammation and Ferroptosis

Journal of Inflammation Research
Yueying Liu,1,* Shengjie Xu,1,* Yufan Luo,1,* Xue Xiao,1 Xiaofan Jiang,1 Wei Xiao,1 Ruijin Xie,1 Xianhui Deng,2 Zhen Li,3 Yingsi Cao,1 Yuanjin Chang,1 Dongqin Wu,1 Hua Xu,1 Wenjing Zhao4 1Department of Pediatrics, Affiliated ...
Liu Y, Xu S, Luo Y, Xiao X, Jiang X, Xiao W, Xie R, Deng X, Li Z, Cao Y, Chang Y, Wu D, Xu H, Zhao W   +13 more
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Stereoselective Synthesis of Maresin-like Lipid Mediators

Stereoselective Synthesis of Maresin-like Lipid Mediators
identifier:oai:t2r2.star.titech.ac.jp ...
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