Results 61 to 70 of about 2,016 (189)
Maresins: anti-inflammatory pro-resolving mediators with therapeutic potential.
European review for medical and pharmacological sciences, 2020 Although inflammation is protective of the body, uncontrolled acute inflammatory reactions may inflict tissue damage and lead to chronic inflammation. There is a fast-growing research interest in mechanisms that mediate regression of inflammation and actions of anti-inflammatory factors.
Li, Q.-F. +4 more
openaire +2 more sources
Biosynthesis of the Maresin Intermediate, 13S,14S-Epoxy-DHA, by Human 15-Lipoxygenase and 12-Lipoxygenase and Its Regulation through Negative Allosteric Modulators [PDF]
, 2020 Human reticulocyte 15-lipoxygenase-1 (h15-LOX-1 or ALOX15) and platelet 12-lipoxygenase (h12-LOX or ALOX12) catalysis of docosahexaenoic acid (DHA) and the maresin precursor, 14S-hydroperoxy-4Z,7Z,10Z,12E,16Z,19Z-docosahexaenoic acid (14S-HpDHA), were ...
Tourdot, Benjamin E +7 more
core +1 more source
Maresin 1 modulates renal and cardiac lipid profiles in hypertensive rats. [PDF]
Am J Physiol Renal PhysiolThis study shows that MaR1, a specialized proresolving mediator, influences lipid metabolism and modifies gene expression in the heart and kidney in a salt-sensitive hypertension model, without affecting blood pressure or organ structure. These findings highlight the potential role of MaR1 in regulating inflammation and circadian rhythms associated ...
Bohovyk R +7 more
europepmc +3 more sources
Maresin conjugates in tissue regeneration-1 suppresses ferroptosis in septic acute kidney injury
Cell & Bioscience, 2021 Background Ferroptosis is unique among different types of regulated cell death and closely related to organ injury. Whether ferroptosis occurs in sepsis-associated acute kidney injury (SA-AKI) is not clear.
Ji Xiao +7 more
doaj +1 more source
Maresin conjugates in tissue regeneration biosynthesis enzymes in human macrophages [PDF]
Proceedings of the National Academy of Sciences, 2016 Significance We recently uncovered a family of macrophage-derived molecules, coined maresin conjugates in tissue regeneration, that regulate the system’s ability to clear bacteria as well as repair and regenerate damaged tissues. In the present study, we identified enzymes involved in the formation of these potent molecules in human ...
Dalli, Jesmond +7 more
openaire +4 more sources
The relationship between cholangiocellular carcinoma and maresin 1
, 2021 Tıp Fakültesi, İç Hastalıkları Ana Bilim DalıGiriş ve Amaç: Kolanjioselüler karsinoma (KSK), safra yolları epitel hücrelerinden köken alan, adenokanser yapısında olan malign bir tümördür.
Karatlı, Salih
core
, 2022 Supplemental material, sj-pdf-1-jdr-10.1177_00220345221090879 for Periodontal Stem Cells Synthesize Maresin Conjugate in Tissue Regeneration 3 by A. Rakian, R. Rakian, A.E. Shay, C.N. Serhan and T.E.
A.E. Shay (12425200) +4 more
core +1 more source
The relationship between maresin 1 levels and disease activity in Crohn's disease patients
, 2022 Amaç: Bu çalışmada amacımız, antiinflamatuar ve inflamasyon çözücü özelliklere sahip olan maresin 1 düzeylerinin Crohn hastalarında, hastalık aktivitesi üzerindeki etkisini diğer inflamatuar parametrelerle karşılaştırarak belirlemektir. Materyal ve Metod:
Turan, Tuna
core
Neural Regeneration ResearchSpecialized pro-resolving lipid mediators including maresin 1 mediate resolution but the levels of these are reduced in Alzheimer’s disease brain, suggesting that they constitute a novel target for the treatment of Alzheimer’s disease to prevent/stop ...
Ying Wang +8 more
doaj +1 more source
Maresin 1 and CHI3L1 Levels Exhibit Opposing Trends and Correlations with Renal Dysfunction in Diabetic Nephropathy. [PDF]
Medicina (Kaunas)Background and Objectives: This study aimed to investigate the relationship between Maresin-1 (MaR1), Chitinase-3-like protein 1 (CHI3L1), and inflammatory as well as hematological markers in patients with type 2 diabetes mellitus (T2DM) and diabetic ...
Bulu A +8 more
europepmc +2 more sources