Results 111 to 120 of about 1,949 (158)

Serum biomarker screening and metabolic profiling analysis of nonalcoholic fatty liver disease patients using untargeted metabolomics and machine learning techniques

Frontiers in Molecular Biosciences
Background and ObjectiveNon-alcoholic fatty liver disease (NAFLD) represents the most prevalent chronic hepatic metabolic disorder globally. Without timely intervention, it can progress to non-alcoholic steatohepatitis (NASH), liver fibrosis, and even ...
Lijuan Dan, Huan Shi, Lina Cao, Xiuyan Li, Lirui Kong, Xiaojie You, Wenping Liu, Yanwei Hao, Dong Wang, Hongfei Song, Jie Mu, Qiao Li   +11 more
doaj   +1 more source

Synthesis of maresin 1 and (7S)-isomer

Synthesis of maresin 1 and (7S)-isomer
identifier:oai:t2r2.star.titech.ac.jp ...
openaire  

The effect of cardiopulmonary bypass on Maresin-1 levels and implications for cardiac function

Journal of Medical and Dental Investigations
Aim: Cardiopulmonary bypass (CPB) surgery causes changes in biomarkers associated with inflammatory responses and cardiac stress. Maresin-1 is a novel lipid mediator involved in inflammation resolution, and its role in cardiac function and its prognostic value postoperatively have not yet been sufficiently investigated.
Bişar Amaç, Mustafa Abanoz, Mesut Engin   +2 more
openaire   +1 more source

The specialized pro-resolving lipid mediator maresin 1 protects hepatocytes from lipotoxic and hypoxia-induced endoplasmic reticulum stress.

Endoplasmic reticulum (ER) stress and activation of the unfolded protein response (UPR) are hallmarks of nonalcoholic fatty liver disease (NAFLD), which is the hepatic manifestation of the metabolic syndrome associated with obesity.
Rius, Bibiana, Titos Rodríguez, Esther, Casulleras, Mireia, Duran Güell, Marta, Alcaraz-Quiles, José, Lopategi, Aritz, Flores Costa, Roger, Clària i Enrich, Joan, López-Vicario, Cristina, Lozano, Juanjo   +9 more
core  

Resolution of post-lung transplant ischemia-reperfusion injury is modulated via Resolvin D1-FPR2 and Maresin 1-LGR6 signaling. [PDF]

J Heart Lung Transplant, 2023
Leroy V, Cai J, Tu Z, McQuiston A, Sharma S, Emtiazjoo A, Atkinson C, Upchurch GR, Sharma AK.   +8 more
europepmc   +1 more source

The pro-resolving lipid mediator Maresin 1 ameliorates pain responses and neuroinflammation in the spared nerve injury-induced neuropathic pain: A study in male and female mice. [PDF]

PLoS One, 2023
Teixeira-Santos L, Martins S, Sousa T, Albino-Teixeira A, Pinho D.   +4 more
europepmc   +1 more source

Maresin 1 Alleviates Diabetic Kidney Disease via LGR6-Mediated cAMP-SOD2-ROS Pathway. [PDF]

Oxid Med Cell Longev, 2022
Li X, Xu B, Wu J, Pu Y, Wan S, Zeng Y, Wang M, Luo L, Zhang F, Jiang Z, Xu Y.   +10 more
europepmc   +1 more source

Maresin-1 Alleviates Sepsis-Induced Liver Injury by Regulating Apoptosis and Autophagy via Activation of the PI3K/Akt Signaling Pathway in Mice. [PDF]

Curr Issues Mol Biol
Wang H, Sun M, Fan H.
europepmc   +1 more source

Maresin-1 Prevents Liver Fibrosis by Targeting Nrf2 and NF-κB, Reducing Oxidative Stress and Inflammation. [PDF]

Cells, 2021
Rodríguez MJ, Sabaj M, Tolosa G, Herrera Vielma F, Zúñiga MJ, González DR, Zúñiga-Hernández J.   +6 more
europepmc   +1 more source

Low serum Maresin-1 levels are associated with non-alcoholic fatty liver disease: a cross-sectional study. [PDF]

Lipids Health Dis, 2021
Fang X, Wang H, Ye T, Fu X, Tan X, Zeng Y, Fan J, Xu Y.   +7 more
europepmc   +1 more source