Results 111 to 120 of about 1,753 (136)
Maresin 1 biosynthesis during platelet–neutrophil interactions is organ-protective [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2014 Significance Neutrophil accumulation is fundamental to acute inflammation. In response to tissue injury, circulating neutrophil–platelet aggregates (N-PAs) form for secondary capture. Counterregulation of acute inflammatory processes by specialized proresolving mediators is essential to mitigate collateral injury to healthy bystander ...
Jesmond Dalli +2 more
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Maresin 1 intervention reverses experimental pulmonary arterial hypertension in mice
British Journal of Pharmacology, 2022Background and PurposePulmonary arterial hypertension (PAH) is a pulmonary vasculature obstructive disease that leads to right heart failure and death. Maresin 1 is an endogenous lipid mediator known to promote inflammation resolution. However, the effect of Maresin 1 on PAH remains unclear.Experimental ApproachThe serum Maresin 1 concentration was ...
Aaron Scott, Hui Li
exaly +3 more sources
Relationship between pancreatic cancer and Maresin 1
Journal of Current Hematology & Oncology Research, 2023Aims: Pancreatic cancer is the 4th most common cause of death from cancer. In addition, pancreatic cancer is the most common primary malignant tumor of the pancreas. There are many risk factors for pancreatic cancer, including age, certain genetic syndromes, smoking, diabetes, alcohol abuse and obesity.
Hakan Varol +5 more
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Serum Maresin 1 levels in idiopathic acute anterior uveitis patients
Journal Français d'Ophtalmologie, 2022The purpose of the present study is to assess the levels of Maresin 1 (MaR1) in patients with idiopathic acute anterior uveitis (IAAU) and to compare the MaR1 results with healthy controls.This study includes 24 patients with idiopathic AAU and 24 healty controls (C). The serum MaR1 levels were analyzed using enzyme-linked immunosorbent assays (ELISA).
F.C. Gül +4 more
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Identification of Metabolites of Maresin 1 in Human Neutrophils
The FASEB Journal, 2017The resolution of inflammation, once considered to be rather passive, is now understood to be a complex, regulated process. One of the components in this process is the action of pro‐resolving lipid mediators, including lipoxins, resolvins, protectins and maresins.
Miguel A Gijón +4 more
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Maresin 1 Maintains the Permeability of Lung Epithelial Cells In Vitro and In Vivo
Inflammation, 2016Previous reports showed that Maresin 1 (MaR1) possessed organ protection effects and could attenuate acute lung injury. Here, we aim to figure out whether MaR1 can maintain the permeability of lung epithelial cells by regulating the expression of tight junction protein during lung injury.
Lin, Chen +7 more
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Are decreased serum Maresin 1 levels predictive of cholangiocarcinoma?
Journal of Current Hematology & Oncology ResearchAims: Cholangiocarcinoma (CC) is a rare form of adenocarcinoma originating from the epithelial cells of the biliary tract. Chronic inflammation is known to be a risk factor for this tumor. The present study aimed to investigate whether serum levels of Maresin 1 (MaR1) (a macrophage-derived anti-inflammatory lipid mediator) were associated with the ...
Salih Karatlı +4 more
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Maresin 1 activates brown adipocytes metabolism
2018Brown adipose tissue (BAT) is the main site for adaptive heat production through non-shivering thermogenesis. BAT has been brought to attention, since it provides a protective mechanism against excessive body weight and fat mass accumulation. Recently, it has been suggested emerging roles of BAT activation in the regulation of metabolism, including ...
Laiglesia, Laura M. +3 more
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Association of Low Serum Maresin-1 Levels with Hepatocellular Carcinoma in Cirrhotic Liver
Clinical LaboratoryMaresin-1 (MaR1) is a macrophage-derived antiinflammatory lipid mediator that negatively regulates oxidative and proinflammatory cytokines and also restores integrity in various tissues after inflammation. Non-resolving inflammation is known to have an important role in the pathogenesis of hepatocellular carcinoma (HCC).
Ergül, Bilal +5 more
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