Results 91 to 100 of about 1,949 (158)

Maresin 1 Biosynthesis and Proresolving Anti-infective Functions with Human-Localized Aggressive Periodontitis Leukocytes

, 2019
Localized aggressive periodontitis (LAP) is a distinct form of early-onset periodontitis linked to periodontal infection with uncontrolled inflammation and leukocyte-mediated tissue destruction.
Chiang, Nan, Dalli, Jesmond, Arnardottir, Hildur, Serhan, Charles, Colas, Romain, Hasturk, Hatice, Van Dyke, Thomas E., Wang, Chin-Wei, Nguyen, Daniel   +8 more
core   +1 more source

The future of periodontology: Emerging technologies and conceptual shifts

Journal of Periodontology, Volume 97, Issue 5, Page 875-882, May 2026.
Abstract Periodontology is entering a transformative era driven by advances in diagnostics, therapeutics, and digital integration. Emerging technologies and conceptual shifts are currently reshaping the specialty, with a focus on predictive, preventive, and personalized care.
Michael S. Reddy
wiley   +1 more source

Eicosapentaenoic and Docosahexaenoic Acid Levels in Mouse Tissues After Intake of Echium and Ahiflower Oils Rich in Stearidonic and α‐Linolenic Acids

Lipids, Volume 61, Issue 3, Page 417-426, May 2026.
Dietary supplementation with stearidonic acid–rich Echium and Ahiflower oils increases EPA levels across multiple mouse tissues, while DHA responses remain tissue‐specific and limited, supporting the strategic use of plant‐based omega‐3 sources for EPA‐focused interventions. ABSTRACT Omega‐3 fatty acids (n‐3 FA), particularly eicosapentaenoic acid (EPA)
Letícia V. Segre, Mariana S. Bisinotto, Inar A. Castro   +2 more
wiley   +1 more source

Protectin D1 and maresin 1 attenuate airway hyperreactivity induced by IL‐13 in human isolated small bronchi

British Journal of Pharmacology, Volume 183, Issue 9, Page 2049-2060, May 2026.
Background and Purpose Interleukin (IL)‐13 is implicated in airway hyperreactivity (AHR), a key feature of asthma. We explored the potential anti‐AHR activity of selected specialised pro‐resolving mediators (SPMs) in IL‐13‐induced AHR models, using human bronchial smooth muscle cells (BSMCs) and human isolated bronchi.
Willem Abma, Sven‐Erik Dahlén, Craig E. Wheelock, Mikael Adner, Mamdoh Al‐Amerie, Erik Sachs, Kasra Vali Jalali, Leonardo De Maria, Henric Olsson, Jesper Säfholm   +9 more
wiley   +1 more source

Resolvin D5 Inhibits CXCL8 Expression in Colonic Epithelial Cells Through Activating GPR101 to Impede Neutrophil Recruitment and Consequently Alleviate Ulcerative Colitis

Advanced Science, Volume 13, Issue 21, 13 April 2026.
RvD5 effectively alleviates UC by inhibiting STAT1 signaling to reduce CXCL8 expression in colonic epithelial cells via activation of GPR101, which subsequently decreases the infiltration of neutrophils in the colonic mucosal epithelium. Epimedin A1, a natural allosteric inhibitor of 5‐LOX, demonstrates potential as a therapeutic agent for UC by ...
Pengxiang Guo, Yilei Guo, Yanrong Zhu, Ke Yan, Yulai Fang, Jiafeng Zhang, Yue He, Zhifeng Wei, Yufeng Xia, Yue Dai   +9 more
wiley   +1 more source

Hlutverk maresin 1 og viðtaka þess LGR6 í bólguhjöðnun í ósæðarlokum og kölkun þeirra

, 2021
Failure to engage pro-resolving processes during the inflammatory response may lead to chronic inflammation, which is the underlying cause of many prevalent diseases.
Erna María Jónsdóttir 1995-
core  

Maresin 1 Mitigates Sepsis-Associated Acute Kidney Injury in Mice via Inhibition of the NF-κB/STAT3/MAPK Pathways

Frontiers in Pharmacology, 2019
Acute kidney injury (AKI) is one of the most common and serious complications of sepsis in which the inflammatory cascade plays a crucial role. There is now increasing evidence that lipid mediators derived from the omega-3 fatty acid docosahexaenoic acid
ShuJun Sun, ShuJun Sun, JiaMei Wang, JingXu Wang, JingXu Wang, FuQuan Wang, FuQuan Wang, ShangLong Yao, ShangLong Yao, HaiFa Xia, HaiFa Xia   +10 more
doaj   +1 more source

Maresin 1 Resolves Inflammation and Aids Bone Healing in Periapical Lesions

Journal of Dental Research
Chronic apical periodontitis (CAP) is a persistent inflammatory condition caused by microbial infections in the root canal system, leading to bone loss and tissue damage. In this study, we tested the hypothesis that maresin 1 (MaR1), a specialized proresolving mediator, facilitates inflammatory resolution and promotes bone healing ...
E. Demir, I. İlgenli, Z. Guney, S. Mohammadi, K. Lauwens, N. Yakar, C. Alvarez Rivas, O. Unlu, A. Kantarci   +8 more
openaire   +2 more sources

Additional file 1 of Administration of Maresin-1 ameliorates the physiopathology of experimental autoimmune encephalomyelitis

, 2022
Additional file 1. Fig. S1. MaR1 reduces the accumulation of immune cells in the spinal cord of mice at the peak of EAE. Fig. S2. MaR1 modulates T cells responses in the spinal cord of EAE mice. Fig. S3. MaR1 modulates the macrophages and microglia phenotypes towards a more anti-inflammatory phenotype. Fig. S4. Effects of the treatment with MaR1 in the
Sánchez-Fernández, Alba, Zandee, Stephanie, Mastrogiovanni, Mauricio, Charabati, Marc, Rubbo, Homero, Prat, Alexandre, López-Vales, Rubèn   +6 more
openaire   +1 more source

The Pro-resolving Mediators Maresin 1, Maresin 2 and Annexin A1 in Maintenance of Ocular Surface Health

, 2022
The omega-3 fatty acids Maresin 1 and Maresin 2 and the protein Annexin A1 are pro-resolving mediators which play an active role in resolution of inflammation. The mediators enhance elimination of apoptotic cells, activation of immune cells and limit invasion of leukocytes.
openaire   +2 more sources