Results 81 to 90 of about 1,753 (136)

Macrophage proresolving mediator maresin 1 stimulates tissue regeneration and controls pain

The FASEB Journal, 2012
Self‐resolving inflammatory exudates and lipid mediator metabolomics recently uncovered a new family of potent anti‐inflammatory and proresolving mediators biosynthesized by macrophages (MΦs), denoted maresins. Here we determined that maresin 1 (MaR1) produced by human MΦs from endogenous docosahexaenoic acid (DHA) matched ...
Charles N, Serhan, Jesmond, Dalli, Sergey, Karamnov, Alexander, Choi, Chul-Kyu, Park, Zhen-Zhong, Xu, Ru-Rong, Ji, Min, Zhu, Nicos A, Petasis   +8 more
openaire   +3 more sources

Does exercise enhance maresin-1 production? A new direction in metabolic anti-inflammatory research [PDF]

Exploration of Immunology
Obesity is a major global health challenge characterized by chronic low-grade inflammation and metabolic dysfunction. Among lipid-derived mediators involved in inflammation resolution, maresin-1 (MaR1)—a specialized pro-resolving mediator derived from ...
Mehran Alipour, Ayoub Saeidi, Maryam N. ALNasser, Khadija Ayed, Abdullah Almaqhawi, Keyvan Hejazi, Hassane Zouhal   +6 more
doaj   +1 more source

Synthesis of maresin 1 and (7S)-isomer

Synthesis of maresin 1 and (7S)-isomer
identifier:oai:t2r2.star.titech.ac.jp ...
openaire  

Maresin 1 mitigates renal ischemia/reperfusion injury in mice via inhibition of the TLR4/MAPK/ NF-κB pathways and activation of the Nrf2 pathway

Drug Design, Development and Therapy, 2019
Yun Qiu, Yichen Wu, Hongmei Zhao, Hong Sun, Sumin Gao Department of Emergency Medicine, The Affiliated Huaian No 1 People’s Hospital of Nanjing Medical University, Huai’an, Jiangsu Province, China Background: Inflammation and oxidative ...
Qiu Y, Wu Y, Zhao H, Sun H, Gao S
doaj  

Maresin 1 (MaR1) [PDF]

Science-Business eXchange, 2014
openaire   +1 more source

The effect of cardiopulmonary bypass on Maresin-1 levels and implications for cardiac function

Journal of Medical and Dental Investigations
Aim: Cardiopulmonary bypass (CPB) surgery causes changes in biomarkers associated with inflammatory responses and cardiac stress. Maresin-1 is a novel lipid mediator involved in inflammation resolution, and its role in cardiac function and its prognostic value postoperatively have not yet been sufficiently investigated.
Bişar Amaç, Mustafa Abanoz, Mesut Engin   +2 more
openaire   +1 more source

Maresin-like 1 Ameliorates Neuropathology of Alzheimer's Disease in Brains of a Transgenic Mouse Model

Biomedicines
1) Background: Impeded resolution of inflammation contributes substantially to the pathogenesis of Alzheimer's disease (AD); consequently, resolving inflammation is pivotal to the amelioration of AD pathology. This can potentially be achieved by the treatment with specialized pro-resolving lipid mediators (SPMs), which should resolve neuroinflammation ...
Pallavi Shrivastava, Yan Lu, Shanchun Su, Yuichi Kobayashi, Yuhai Zhao, Nathan Lien, Abdul-Razak Masoud, Walter J. Lukiw, Song Hong   +8 more
openaire   +3 more sources

Pro-resolving mediator maresin 1 ameliorates pain hypersensitivity in a rat spinal nerve ligation model of neuropathic pain

Journal of Pain Research, 2018
Jie Gao,1,2,* Chaoliang Tang,3,4,* Lydia Wai Tai,5 Yeling Ouyang,2,6 Na Li,2,6 Zhiqiang Hu,2,6 Xiangdong Chen2,6 1Department of Anesthesiology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, Anhui Provence, China; 2Department ...
Gao J, Tang C, Tai LW, Ouyang Y, Li N, Hu Z, Chen X   +6 more
doaj  

Resolution of post-lung transplant ischemia-reperfusion injury is modulated via Resolvin D1-FPR2 and Maresin 1-LGR6 signaling. [PDF]

J Heart Lung Transplant, 2023
Leroy V, Cai J, Tu Z, McQuiston A, Sharma S, Emtiazjoo A, Atkinson C, Upchurch GR, Sharma AK.   +8 more
europepmc   +1 more source

The pro-resolving lipid mediator Maresin 1 ameliorates pain responses and neuroinflammation in the spared nerve injury-induced neuropathic pain: A study in male and female mice. [PDF]

PLoS One, 2023
Teixeira-Santos L, Martins S, Sousa T, Albino-Teixeira A, Pinho D.   +4 more
europepmc   +1 more source