Results 61 to 70 of about 1,949 (158)

Biosynthesis of the Maresin Intermediate, 13S,14S-Epoxy-DHA, by Human 15-Lipoxygenase and 12-Lipoxygenase and Its Regulation through Negative Allosteric Modulators [PDF]

, 2020
Human reticulocyte 15-lipoxygenase-1 (h15-LOX-1 or ALOX15) and platelet 12-lipoxygenase (h12-LOX or ALOX12) catalysis of docosahexaenoic acid (DHA) and the maresin precursor, 14S-hydroperoxy-4Z,7Z,10Z,12E,16Z,19Z-docosahexaenoic acid (14S-HpDHA), were ...
Tourdot, Benjamin E, Jacobson, Matthew P, Holinstat, Michael, Perry, Steve, Tran, Adrianne, Holman, Theodore R, Freedman, Cody, Kalyanaraman, Chakrapani   +7 more
core   +1 more source

The relationship between cholangiocellular carcinoma and maresin 1

, 2021
Tıp Fakültesi, İç Hastalıkları Ana Bilim DalıGiriş ve Amaç: Kolanjioselüler karsinoma (KSK), safra yolları epitel hücrelerinden köken alan, adenokanser yapısında olan malign bir tümördür.
Karatlı, Salih
core  

Subfatin, asprosin, alamandine and maresin-1 in cerebral ischemia, intracranial and subarachnoid hemorrhages.

European review for medical and pharmacological sciences, 2023
Cerebrovascular diseases (CVDs) remain an important public health issue due to the increasing number of deaths worldwide. Changes in the synthesis and release of peptides in CVDs may play an important role in elucidating the physiopathology of the disease. Therefore, this study was to investigate the fate of maresin-1 (MaR-1), subfatin (SUB), asprosin (
Albayrak, S., Aydin, M.A., Ugur, K., Hanbeyoglu, O., Aydin, S., Erol, E., Kilinc, A., Acar, V., Sahin, İ., Aydin, S.   +9 more
openaire   +2 more sources

Association between pancreatic cancer and maresin 1

, 2022
Pankreas kanseri ile Maresin 1 arasındaki ilişki, Kırıkkale Üniversitesi Tıp Fakültesi İç Hastalıkları Anabilim Dalı, Uzmanlık Tezi, Kırıkkale, 2022. Giriş ve Amaç: Pankreas kanseri, kansere bağlı ölümlerde 4. sıradadır ve pankreas kanseri, pankreasın en
Varol, Hakan
core  

Maresin 1 regulates peripheral leukocyte responses in patients with chronic eosinophilic nasal polyposis [PDF]

, 2023
The discovery of specialized pro-resolving mediators (SPM) has changed our understanding of inflammation leading to an appreciation for the role of dysregulated SPM pathways in chronic disease.
Beegun, I
core  

Pro-resolving lipid mediator reduces amyloid-β42–induced gene expression in human monocyte–derived microglia

Neural Regeneration Research
Specialized pro-resolving lipid mediators including maresin 1 mediate resolution but the levels of these are reduced in Alzheimer’s disease brain, suggesting that they constitute a novel target for the treatment of Alzheimer’s disease to prevent/stop ...
Ying Wang, Xiang Zhang, Henrik Biverstål, Nicolas G. Bazan, Shuai Tan, Nailin Li, Makiko Ohshima, Marianne Schultzberg, Xiaofei Li   +8 more
doaj   +1 more source

Maresin conjugates in tissue regeneration-1 suppresses ferroptosis in septic acute kidney injury

Cell & Bioscience, 2021
Background Ferroptosis is unique among different types of regulated cell death and closely related to organ injury. Whether ferroptosis occurs in sepsis-associated acute kidney injury (SA-AKI) is not clear.
Ji Xiao, Qian Yang, Ye’an Zhang, Haoran Xu, Yang Ye, Linchao Li, Yi Yang, Shengwei Jin   +7 more
doaj   +1 more source

Peripheral targets for neuropathic pain

British Journal of Pharmacology, EarlyView.
Neuropathic pain represents a significant clinical challenge, with still limited pharmacological approaches to symptomatic relief. This review focuses on molecular targets implicated in neuropathic pain, particularly those involved in peripheral mechanisms. Using the IUPHAR/BPS database of biological targets, their occurrence together with ‘neuropathic
Amirhossein Afsharipour, Cosmin I. Ciotu, Felix J. Resch, Michael J. M. Fischer   +3 more
wiley   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

The relationship between maresin 1 levels and disease activity in Crohn's disease patients

, 2022
Amaç: Bu çalışmada amacımız, antiinflamatuar ve inflamasyon çözücü özelliklere sahip olan maresin 1 düzeylerinin Crohn hastalarında, hastalık aktivitesi üzerindeki etkisini diğer inflamatuar parametrelerle karşılaştırarak belirlemektir. Materyal ve Metod:
Turan, Tuna
core