Results 41 to 50 of about 1,949 (158)
Resolving Lipid Mediators Maresin 1 and Resolvin D2 Prevent Atheroprogression in Mice [PDF]
Circulation Research, 2016 Rationale: Atheroprogression is a consequence of nonresolved inflammation, and currently a comprehensive overview of the mechanisms preventing resolution is missing. However, in acute inflammation, resolution is known to be orchestrated by a switch from inflammatory to resolving lipid mediators ...
Viola, Joana R. +13 more
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Drug Design, Development and Therapy, 2019 Yun Qiu, Yichen Wu, Hongmei Zhao, Hong Sun, Sumin Gao Department of Emergency Medicine, The Affiliated Huaian No 1 People’s Hospital of Nanjing Medical University, Huai’an, Jiangsu Province, China Background: Inflammation and oxidative ...
Qiu Y, Wu Y, Zhao H, Sun H, Gao S
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Journal of Pain Research, 2018 Jie Gao,1,2,* Chaoliang Tang,3,4,* Lydia Wai Tai,5 Yeling Ouyang,2,6 Na Li,2,6 Zhiqiang Hu,2,6 Xiangdong Chen2,6 1Department of Anesthesiology, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, Anhui Provence, China; 2Department ...
Gao J +6 more
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Maresin 1 Ameliorates Diabetic Kidney Disease in Mice by Promoting Macrophage M2 Polarization [PDF]
Mediators of InflammationYueli Pu +8 more
doaj +2 more sources
Biomedicines1) Background: Impeded resolution of inflammation contributes substantially to the pathogenesis of Alzheimer's disease (AD); consequently, resolving inflammation is pivotal to the amelioration of AD pathology. This can potentially be achieved by the treatment with specialized pro-resolving lipid mediators (SPMs), which should resolve neuroinflammation ...
Pallavi Shrivastava +8 more
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The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Specialized pro-resolving mediator Maresin 1 attenuates pain in a mouse model of osteoarthritis [PDF]
Osteoarthritis and CartilageYu-Ru V Shih +2 more
exaly +2 more sources
Identification and Actions of the Maresin 1 Metabolome in Infectious Inflammation [PDF]
The Journal of Immunology, 2016 Abstract Maresin 1 (MaR1) is an immunoresolvent that governs resolution of acute inflammation, and its local metabolism in the context of infectious inflammation is of interest. In this study, we investigated the MaR1 metabolome in infectious exudates and its bioactions in regulating leukocyte responses in the context of bacterial ...
Romain A Colas +6 more
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Southern Clinics of Istanbul Eurasia, 2020 INTRODUCTION[|]The purpose of this study is to examine the protective effects of maresin 1 on testicular injury induced by ischemia reperfusion. [¤]METHODS[|]24 Sprague-Dawley male rats were divided into 3 groups. The groups are planned as follows; sham,
Ayhan Tanyeli +6 more
doaj +1 more source
Frontiers in Neuroscience, 2020 BackgroundThe exposure of the nucleus pulposus (NP) causes an immune and inflammatory response, which is intrinsically linked to the pathogenesis of radicular pain. As a newly discovered pro-resolving lipid mediator, maresin 1 (MaR1) could exert powerful
Yi-hao Wang +8 more
doaj +1 more source