Maresin 1 activates brown adipose tissue and promotes browning of white adipose tissue in mice [PDF]
Molecular Metabolism, 2023 Objective: Maresin 1 (MaR1) is a docosahexaenoic acid-derived proresolving lipid mediator with insulin-sensitizing and anti-steatosis properties. Here, we aim to unravel MaR1 actions on brown adipose tissue (BAT) activation and white adipose tissue (WAT)
Laura M. Laiglesia +19 more
doaj +2 more sources
Maresin 1 Exerts a Tissue-Specific Regulation of Adipo-Hepato-Myokines in Diet-Induced Obese Mice and Modulates Adipokine Expression in Cultured Human Adipocytes in Basal and Inflammatory Conditions [PDF]
Biomolecules, 2023 This study analyses the effects of Maresin 1 (MaR1), a docosahexaenoic acid (DHA)-derived specialized proresolving lipid mediator with anti-inflammatory and insulin-sensitizing actions, on the expression of adipokines, including adiponectin, leptin ...
Leyre Martínez-Fernández +6 more
doaj +2 more sources
Plasma and aqueous humor levels of Maresin-1 in patients with diabetic retinopathy [PDF]
Scientific ReportsThe aim of this study was to evaluate plasma and aqueous Maresin-1 (MaR1) levels in patients with diabetic retinopathy (DR) and to examine the ability of these levels to distinguish proliferative diabetic retinopathy.
Sabiha Güngör Kobat +8 more
doaj +2 more sources
Frontiers in Cellular Neuroscience, 2019 Alzheimer’s disease (AD) is one of the most common neurodegenerative disease. Accumulating evidences suggest an active role of inflammation in the pathogenesis of AD.
Jiachun Feng +2 more
exaly +3 more sources
Decreased Plasma Maresin 1 Concentration Is Associated with Diabetic Foot Ulcer [PDF]
Mediators of Inflammation, 2020 Aims. To assess the maresin 1 (MaR1) contents in type 2 diabetic patients with or without diabetic foot ulcer and to analyze the association of MaR1 concentrations with several metabolism-related parameters. Methods.
Tian Miao +9 more
doaj +3 more sources
Serum Resolvin D1 and Maresin 1 Levels During Migraine Attacks and the Interictal Period: A Paired Analysis in Emergency Department Patients [PDF]
BiomedicinesBackground/Objectives: Neurogenic inflammation plays a key role in migraine pathophysiology. This study aimed to evaluate serum Resolvin D1 (RvD1) and Maresin 1 (MaR1) levels during acute migraine attacks and in the interictal period in the same patients,
Miraç Koç +2 more
doaj +2 more sources
Maresin 1 Mitigates Inflammatory Response and Protects Mice from Sepsis [PDF]
Mediators of Inflammation, 2016 Sepsis, frequently caused by infection of bacteria, is considered as an uncontrollable systematic inflammation response syndrome (SIRS). Maresin 1 (Mar1) is a new proresolving mediator with potent anti-inflammatory effect in several animal models ...
Ruidong Li +8 more
doaj +3 more sources
Maresin-1 and S-Equol as Emerging Metabolic Biomarkers in Gestational Diabetes-Associated Inflammation [PDF]
DiagnosticsBackground/Objectives: The most prevalent metabolic condition during pregnancy is gestational diabetes mellitus (GDM), typically diagnosed in the second or third trimester and absent prior to gestation, with a reported prevalence ranging between 1% and ...
Seyda Yavuzkir +4 more
doaj +2 more sources
Maresin 1 and CHI3L1 Levels Exhibit Opposing Trends and Correlations with Renal Dysfunction in Diabetic Nephropathy [PDF]
MedicinaBackground and Objectives: This study aimed to investigate the relationship between Maresin-1 (MaR1), Chitinase-3-like protein 1 (CHI3L1), and inflammatory as well as hematological markers in patients with type 2 diabetes mellitus (T2DM) and diabetic ...
Aykut Bulu +8 more
doaj +2 more sources
Impact of Resolvin-E1 and Maresin-1 on Bone Marrow Stem Cell Osteogenesis under Inflammatory Stress [PDF]
CellsPeriodontal disease is characterized by inflammation and bone loss. Central to its pathogenesis is the dysregulated inflammatory response, complicating regenerative therapies.
Shahd AlZahrani +3 more
doaj +2 more sources