Results 51 to 60 of about 1,949 (158)

Blood, saliva and urine maresin-1 and malondialdehyde may be useful biomarker in patients with polycystic ovary syndrome: a prospective study

Clinical and Experimental Obstetrics & Gynecology, 2022
Background: Maresin-1 (MaR1) plays a major role in many inflammatory disorders. Polycystic ovary syndrome (PCOS) aside from a hormonal disorder, an inflammation might also contribute to PCOS and its metabolic associations.
Adem Yavuz, Kader Ugur, Zuhal Karaca Karagoz, Durmus Ayan, Suleyman Aydin   +4 more
doaj   +1 more source

Maresin 1 attenuates neuroinflammation in a mouse model of perioperative neurocognitive disorders [PDF]

British Journal of Anaesthesia, 2019
Resolution of inflammation is an active and dynamic process after surgery. Maresin 1 (MaR1) is one of a growing number of specialised pro-resolving lipids biosynthesised by macrophages that regulates acute inflammation. We investigated the effects of MaR1 on postoperative neuroinflammation, macrophage activity, and cognitive function in mice.Adult male
Yang, T., Xu, G., Newton, P.T., Chagin, A.S., Mkrtchian, S., Carlström, M., Zhang, X.-M., Harris, R.A., Cooter, M., Berger, M., Maddipati, K.R., Akassoglou, K., Terrando, N.   +12 more
openaire   +2 more sources

Anti-Inflammatory Effect of Specialized Proresolving Lipid Mediators on Mesenchymal Stem Cells: An In Vitro Study

Cells, 2022
An interconnection between tissue inflammation and regeneration has been established through the regulation of defense and repair mechanisms within diseased dental tissue triggered by the release of immune-resolvent mediators. To better our understanding
Shahd AlZahrani, Zakia Shinwari, Ameera Gaafar, Ayodele Alaiya, Ahmed Al-Kahtani   +4 more
doaj   +1 more source

Maresin 1 resolves aged‐associated macrophage inflammation to improve bone regeneration [PDF]

The FASEB Journal, 2020
Abstract Inflammaging is associated with poor tissue regeneration observed in advanced age. Specifically, protracted inflammation after acute injury has been associated with decreased bone fracture healing and increased rates of nonunion in elderly patients.
Huang, Rong, Vi, Linda, Zong, Xiaohua, Baht, Gurpreet S.   +3 more
openaire   +2 more sources

Maresin-1 Attenuates Sepsis-Associated Acute Kidney Injury via Suppressing Inflammation, Endoplasmic Reticulum Stress and Pyroptosis by Activating the AMPK/SIRT3 Pathway. [PDF]

J Inflamm Res
Miaomiao Sun,1– 3,* Fuquan Wang,1– 3,* Haopeng Li,1– 3 Mengyu Li,1– 3 Yu Wang,1– 3 Chenchen Wang,1– 3 Yan Zhang,1– 3 Dingyu Zhang,1– 4 Jianhua Li,5 Shanglong Yao1– 3 1Department of Anesthesiology, Union Hospital, Tongji Medical College, Huazhong ...
Sun M, Wang F, Li H, Li M, Wang Y, Wang C, Zhang Y, Zhang D, Li J, Yao S.   +9 more
europepmc   +2 more sources

sj-pdf-1-jdr-10.1177_00220345221090879 – Supplemental material for Periodontal Stem Cells Synthesize Maresin Conjugate in Tissue Regeneration 3

, 2022
Supplemental material, sj-pdf-1-jdr-10.1177_00220345221090879 for Periodontal Stem Cells Synthesize Maresin Conjugate in Tissue Regeneration 3 by A. Rakian, R. Rakian, A.E. Shay, C.N. Serhan and T.E.
A.E. Shay (12425200), C.N. Serhan (12425203), T.E. Van Dyke (5510435), R. Rakian (12425197), A. Rakian (12425194)   +4 more
core   +1 more source

Maresin 1 biosynthesis during platelet–neutrophil interactions is organ-protective [PDF]

Proceedings of the National Academy of Sciences, 2014
Significance Neutrophil accumulation is fundamental to acute inflammation. In response to tissue injury, circulating neutrophil–platelet aggregates (N-PAs) form for secondary capture. Counterregulation of acute inflammatory processes by specialized proresolving mediators is essential to mitigate collateral injury to healthy bystander tissue ...
Abdulnour, Raja-Elie, Dalli, Jesmond, Colby, Jennifer, Krishnamoorthy, Nandini, Timmons, Jack, Tan, Sook Hwa, Colas, Romain, Petasis, Nicos, Serhan, Charles, Levy, Bruce   +9 more
openaire   +4 more sources

Maresin 1 Improves Cognitive Decline and Ameliorates Inflammation in a Mouse Model of Alzheimer’s Disease

Frontiers in Cellular Neuroscience, 2019
Alzheimer’s disease (AD) is one of the most common neurodegenerative disease. Accumulating evidences suggest an active role of inflammation in the pathogenesis of AD.
Ping Yin, Ping Yin, Xu Wang, Shuang Wang, Yafen Wei, Yafen Wei, Jiachun Feng, Mingqin Zhu   +7 more
doaj   +1 more source

Maresin 1 protects the liver against ischemia/reperfusion injury via the ALXR/Akt signaling pathway

Molecular Medicine, 2021
Background Hepatic ischemia/reperfusion (I/R) injury can be a major complication following liver surgery contributing to post-operative liver dysfunction. Maresin 1 (MaR1), a pro-resolving lipid mediator, has been shown to suppress I/R injury.
Da Tang, Guang Fu, Wenbo Li, Ping Sun, Patricia A. Loughran, Meihong Deng, Melanie J. Scott, Timothy R. Billiar   +7 more
doaj   +1 more source

Maresin 1 induces a novel pro‐resolving phenotype in human platelets [PDF]

Journal of Thrombosis and Haemostasis, 2017
Essentials Specialized proresolving mediators (SPMs) promote the resolution of inflammation. This study sought to investigate the effects of SPMs on human platelet function. The SPM, Maresin 1, enhanced hemostatic, but suppressed inflammatory functions of platelets.
K L, Lannan, S L, Spinelli, N, Blumberg, R P, Phipps   +3 more
openaire   +2 more sources