Results 51 to 60 of about 4,269 (185)
Maresin conjugates in tissue regeneration biosynthesis enzymes in human macrophages [PDF]
Proceedings of the National Academy of Sciences, 2016 Significance We recently uncovered a family of macrophage-derived molecules, coined maresin conjugates in tissue regeneration, that regulate the system’s ability to clear bacteria as well as repair and regenerate damaged tissues. In the present study, we identified enzymes involved in the formation of these potent molecules in human ...
Dalli, Jesmond +7 more
openaire +3 more sources
Decreased Plasma Maresin 1 Concentration Is Associated with Diabetic Foot Ulcer [PDF]
Mediators of Inflammation, 2020 Aims. To assess the maresin 1 (MaR1) contents in type 2 diabetic patients with or without diabetic foot ulcer and to analyze the association of MaR1 concentrations with several metabolism-related parameters. Methods. Plasma MaR1 concentrations were analyzed in 96 subjects with normal glucose tolerant (NC, n=43), type 2 diabetes (T2DM, n=40), or ...
Tian Miao +9 more
openaire +3 more sources
Significance of long chain polyunsaturated fatty acids in human health [PDF]
, 2017 In the last decades, the development of new technologies applied to lipidomics has revitalized the analysis of lipid profile alterations and the understanding of the underlying molecular mechanisms of lipid metabolism, together with their involvement in ...
El Jaber-Vazdekis, Nabil +4 more
core +1 more source
Maresin 1 Mitigates Inflammatory Response and Protects Mice from Sepsis [PDF]
Mediators of Inflammation, 2016 Sepsis, frequently caused by infection of bacteria, is considered as an uncontrollable systematic inflammation response syndrome (SIRS). Maresin 1 (Mar1) is a new proresolving mediator with potent anti-inflammatory effect in several animal models. However, its effect in sepsis is still not investigated.
Ruidong Li +8 more
openaire +3 more sources
Can vagus nerve stimulation halt or ameliorate rheumatoid arthritis and lupus?
Lipids in Health and Disease, 2011 Acetylcholine, the principal vagus neurotransmitter, inhibits inflammation by suppressing the production of pro-inflammatory cytokines through a mechanism dependent on the α7 nicotinic acetylcholine receptor subunit (alpha7nAChR) that explains why vagus ...
Das Undurti N
doaj +1 more source
What makes gouty inflammation so variable? [PDF]
, 2017 Acute gout arthritis flares contribute dominantly to gout-specific impaired health-related quality of life, representing a progressively increasing public health problem.
Terkeltaub, Robert
core +2 more sources
Journal of Advanced Research, 2019 It has been suggested that hepatitis B virus (HBV)- and hepatitis C virus (HCV)-induced hepatic damage and cirrhosis and associated hypoalbuminemia, non-alcoholic fatty liver disease (NAFLD), and alcoholic fatty liver disease (AFLD) are due to an ...
Undurti N. Das
doaj +1 more source
Mediators of Inflammation, 2018 Acute inflammatory responses are host-protective and normally self-limited; these responses can maintain cell homeostasis and promote defense against various infections and damage factors.
Shi Tang +4 more
doaj +1 more source
Frontiers in ImmunologySepsis is a life-threatening syndrome of organ dysfunction, characterized by uncontrolled inflammatory response and immune dysregulation, often leading to multiple organ failure and even death.
Shujun Sun +22 more
doaj +1 more source
Frontiers in Immunology, 2012 The role of inflammation in the pathogenesis of type 2 diabetes mellitus (T2DM) and its associated complications is increasingly recognized. The resolution of inflammation is actively regulated by endogenously produced lipid mediators such as lipoxins ...
Emma eBorgeson, Catherine eGodson
doaj +1 more source