Results 61 to 70 of about 4,269 (185)

Резольвины, протектины и марезины - новые медиаторы воспаления [PDF]

, 2012
воспалениемарезиныпротектинырезольвин
Гребенников, И. Н., Куликов, В. А.   +1 more
core  

Maresin-1 impairs cutaneous wound healing response

ImmunoHorizons
Abstract Maresin-1 is a derivative of docosahexaenoic acid with strong anti-inflammatory action in various disease models. However, these effects may not always be beneficial. In instances like cutaneous diseases in which wound healing is important, inflammation is required.
Reiko Hara, Natsuko Saito-Sasaki, Yu Sawada   +2 more
openaire   +2 more sources

N-3 fatty acids as resolvents of inflammation in the A549 cells [PDF]

, 2015
Background Fatty acids and their derivatives are one of the most crucial inflammation mediators. The aim of our study was to evaluate the impact of polyunsaturated fatty acids as eicosanoids precursors on the A549 cell line.
Czepiel, Jacek, Gdula-Argasińska, Joanna, Grzywacz, Agata, Jurczyszyn, Artur, Librowski, Tadeusz, Perucki, William, Wojtoń, Katarzyna, Woźniakiewicz, Aneta, Woźniakiewicz, Michał   +8 more
core   +1 more source

Unified nexus of macrophages and maresins in cardiac reparative mechanisms [PDF]

The FASEB Journal, 2018
ABSTRACT Macrophages are immune‐sensing “big eater” phagocytic cells responsible for an innate, adaptive, and regenerative response. After myocardial infarction, macrophages predominantly clear the deceased cardiomyocyte apoptotic or necrotic neutrophils to develop a regenerative and reparative program with the ...
Jeevan Kumar, Jadapalli, Ganesh V, Halade   +1 more
openaire   +2 more sources

A defect in Δ⁶ and Δ⁵ desaturases may be a factor in the initiation and progression of insulin resistance, the metabolic syndrome and ischemic heart disease in South Asians

Lipids in Health and Disease, 2010
The high incidence of insulin resistance and the metabolic syndrome in South Asians remains unexplained. I propose that a defect in the activity of Δ6 and Δ5 desaturases and consequent low plasma and tissue concentrations of polyunsaturated fatty acids ...
Das Undurti N
doaj   +1 more source

The DPA-derivative 11S, 17S-dihydroxy 7,9,13,15,19 (Z,E,Z,E,Z)-docosapentaenoic acid inhibits IL-6 production by inhibiting ROS production and ERK/NF-κB pathway in keratinocytes HaCaT stimulated with a fine dust PM10

Ecotoxicology and Environmental Safety, 2022
11 S, 17S-dihydroxy 7,9,13,15,19 (Z,E,Z,E,Z)-docosapentaenoic acid (DoPE) is a derivative of docosapentaenoic acid, a specialized pro-resolving mediator of inflammation such as lipoxins, resolvins, maresins, and protectins.
Myoung-Kwon Choi, Jinju Kim, Hyo-Min Park, Chae-Min Lim, Thu-Huyen Pham, Ha Youn Shin, Seong-Eun Kim, Deok-Kun Oh, Do-Young Yoon   +8 more
doaj   +1 more source

Inflammation and Obesity (Lipoinflammation) [PDF]

, 2016
Obesity is a chronic disease with multiple origins. It is a widespread global phenomenon carrying potentially serious complications which requires a multidisciplinary approach due to the significant clinical repercussions and elevated health costs ...
Domingo i Pedrol, Joan Carles, Izaola, Olatz, Luis, Daniel de, Sajoux, Ignacio, Vidal, Montserrat   +4 more
core   +1 more source

Maresins as novel anti-inflammatory actors and putative therapeutic targets in sepsis

Pharmacological Research
Sepsis, a complex clinical syndrome characterized by an exaggerated host response to infection, often necessitates hospitalization and intensive care unit admission. Delayed or inaccurate diagnosis of sepsis, coupled with suboptimal treatment strategies,
Yan Sun, Shujun Sun, Pu Chen, Yan Dai, Dong Yang, Yun Lin, Lisha Yi   +6 more
doaj   +1 more source

Current experimental methods to investigate the impact of specialized pro-resolving lipid mediators on Sjögren’s syndrome

Frontiers in Immunology, 2023
Sjögren’s syndrome is a chronic inflammatory autoimmune disease characterized by diminished secretory function of the exocrine glands. Although extensive investigation has been done to understand Sjögren’s syndrome, the causes of the disease are as yet ...
Harim T. dos Santos, Harim T. dos Santos, Kihoon Nam, Kihoon Nam, Diana Gil, Diana Gil, Diana Gil, Venkata Yellepeddi, Venkata Yellepeddi, Olga J. Baker, Olga J. Baker, Olga J. Baker   +11 more
doaj   +1 more source

ω3 Polyunsaturated Fatty Acids as Immunomodulators in Colorectal Cancer: New Potential Role in Adjuvant Therapies [PDF]

, 2016
Diet composition may affect the onset and progression of chronic degenerative diseases, including cancer, whose pathogenesis relies on inflammatory processes.
Anna Maria Mileo, Roberta Masella, Sandra Gessani, Stefania Miccadei   +3 more
core   +2 more sources