Results 81 to 90 of about 1,734 (194)
Antiviral Drug Combinations for Viral Infection Treatment [PDF]
, 2023 Enterovirus, som er en del av Picornaviridae-familien, er ansvarlig for et bredt spekter av sykdommer som varierer fra asymptomatiske til dødelige, inkludert utslett, lammelse, hjernehinnebetennelse, poliomyelitt, forkjølelse, hepatitt A og fot-og ...
Anunnitipat, Kraipit
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Journal of Medical Virology, Volume 97, Issue 8, August 2025.ABSTRACT This study introduces a new procedure for antiviral resistance analysis and genetic classification of human cytomegalovirus (HCMV) using next‐generation sequencing (NGS) adapted to existing methodologies, aiming for more targets due to the recent use of new antivirals. It expands the classical investigation of mutations in UL54 and UL97 genes,
Maria Arnedo‐Muñoz +16 more
wiley +1 more source
Recent advances in cytomegalovirus infection management in solid organ transplant recipients [PDF]
Purpose of review Human cytomegalovirus (CMV) continues to be the most important infectious complication following solid organ transplantation (SOT).
Grossi P. A., Peghin M.
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Brazilian Journal of Infectious DiseasesIntroduction: Cytomegalovirus (CMV) infection is one of the main infectious complications in patients undergoing hematopoietic stem cell transplant (BMT), and is associated with significant morbidity and mortality.
Leticia Leite Batista +4 more
doaj +1 more source
Antiviral resistance and persistent replication of cytomegalovirus and SARS-CoV-2 in immunocompromised patients [PDF]
, 2022 [eng] The main objectives of this thesis are to study the opportunistic infection caused by human cytomegalovirus and SARS-CoV-2 inquiring persistent infection and antiviral resistance.
Santos Bravo, Marta
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Pediatric Transplantation, Volume 29, Issue 5, August 2025.ABSTRACT The recently published 4th International Consensus Guidelines on the Management of CMV in Solid‐Organ Transplantation offers updated recommendations for CMV prevention, treatment, and monitoring in pediatric solid organ transplant (pSOT) recipients.
Kevin J. Downes +5 more
wiley +1 more source
Usage of Antivirals and the Occurrence of Antiviral Resistance in Norway 2019. RAVN [PDF]
, 2020 The usage of antivirals According to The Norwegian Drug Wholesales statistics database, the sales of antiviral drugs measured in defined daily doses (DDDs) continued to increase in 2018.
Bragstad, Karoline +5 more
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Drugs in R & D, 2007 Maribavir is a novel benzimidazole riboside compound that is currently in clinical development with ViroPharma for the prevention of cytomegalovirus (CMV) infections in transplant patients. Maribavir is thought to inhibit viral DNA assembly and inhibit egress of viral capsids from infected cell nuclei. This mechanism is different to other available CMV
openaire +2 more sources
Current and Emerging Antiviral Agents in the Prevention and Treatment of Cytomegalovirus in Pediatric Transplant Recipients [PDF]
Despite current prophylaxis regimens, cytomegalovirus (CMV) is common in hematopoietic cell transplantation (HCT) and solid organ transplantation (SOT) and remains a significant cause of morbidity and mortality.
Danziger-Isakov, Lara A +2 more
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Cytomegalovirus UL97 mutations in the era of ganciclovir and maribavir [PDF]
Reviews in Medical Virology, 2008 AbstractMutations in the human CMV UL97 kinase gene are a major mechanism of viral resistance to two anti‐CMV drugs, ganciclovir (GCV) and maribavir (MBV). GCV, the most widely used and established therapy for CMV, is a substrate for the UL97 kinase.
openaire +2 more sources