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Tumor Antigens as Surrogate Markers and Targets for Therapy and Vaccines

2006
There are a large number of tumor antigens, which may either be specific to the tumor or inappropriately expressed or processed (tumor-associated antigen, TAA). Over the last few years, hundreds of new TAAs have been identified. Some of these represent good targets for both passive (antibody based) and active (vaccine based) therapies.
Dalgleish, A, Pandha, H
openaire   +4 more sources

Effect of influenza vaccine on markers of inflammation and lipid profile

Journal of Laboratory and Clinical Medicine, 2005
Despite wide use of the influenza vaccine, relatively little is known about its effect on the measurement of inflammatory markers. Because inflammatory markers such as C-reactive protein (CRP) are increasingly being used in conjunction with lipids for the clinical assessment of cardiovascular disease and in epidemiologic studies, we evaluated the ...
Michael Y, Tsai   +7 more
openaire   +2 more sources

Vaccination markers: designing unique antigens to be added to vaccines to differentiate between natural infection and vaccination

Vaccine, 2005
Some important vaccines, including ones against tuberculosis (Tb) and foot-and-mouth disease (FMD), are not used in many developed countries because there is no simple way to differentiate between vaccine-induced immunity and infection. Eliminating major protein antigens has not succeeded in the cases of Tb, FMD and some other vaccine preparations ...
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Using Infection Markers as a Vaccine against Malware Attacks

2012 IEEE International Conference on Green Computing and Communications, 2012
Malware is used by criminals for financial gains, espionage and sabotage, and their code and evasion techniques become increasingly complex and sophisticated. This means it takes longer for security researchers to analyse a malware and develop detection and removal routines, increasing the danger of critical systems becoming infected.
André Wichmann, Elmar Gerhards-Padilla
openaire   +1 more source

Laboratory markers for over-attenuation of mumps vaccine virus

Vaccine, 1988
The properties of mumps vaccine virus (Leningrad-3 strain) gradually changed upon passaging in quail embryo fibroblasts, the substrate normally used for mumps vaccine production in the USSR. Alterations were extremely noticeable in the over-attenuated (38th passage) virus variant, and involved (a) poor, if any, antibody response in guinea-pigs, (b ...
, Boriskin YuS   +4 more
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Experiences with two BHV1 marker vaccines

The Bovine Practitioner, 1997
Both marker vaccines tested were deleted vaccines, one had a gG, the other a gE deletion. The gG deleted vaccine was inactivated the gE deleted vaccine had a live and an inactivated form. The object of the trial was to evaluate these vaccines in heifers and calves. Twenty young heifers were used for the inactivated deleted vaccines and 16 four week old
openaire   +1 more source

Improvement of serological discrimination between herpesvirus-infected animals and animals vaccinated with marker vaccines

Veterinary Microbiology, 2002
Control/eradication plans of bovine herpesvirus 1 (BHV1) and suid herpesvirus 1 (SHV1) infections involve vaccination with inactivated or attenuated gE-deleted marker vaccines and associated companion serological tests to discriminate naturally infected from vaccinated animals.
D, Lehmann   +3 more
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Immunological Markers of Cancer Vaccine Efficacy and their Clinical Relevance

Biomarkers in Medicine, 2009
As the field of anticancer therapy advances, with a mission to either prevent tumors or improve the quality of life and survival of those affected by the disease, biomarker discovery in oncology is also growing. Since cancer therapy has become a type of personalized medicine, biomarkers are strongly needed in order to identify the right therapy for the
openaire   +2 more sources

Overview of marker vaccine and differential diagnostic test technology

Biologicals, 2005
Recent advances in molecular biology, immunology, microbiology, genetics and microbial pathogenesis have lead to the development of a wide variety of new approaches for developing safer and more effective vaccines based on designs such as subunit vaccines, gene deleted vaccines, live vectored vaccines, and DNA mediated vaccines. Technology tools can be
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An experimental infection with classical swine fever in E2 sub-unit marker-vaccine vaccinated and in non-vaccinated pigs

Vaccine, 2000
The clinical and virological protection induced by an E2 sub-unit marker-vaccine against Classical Swine Fever (CSF) was examined during an experimental infection in vaccinated and non-vaccinated pigs. Forty-five pigs were equally distributed over three adjacent pens of an isolation unit, there was only indirect (airborne) contact between pigs in the ...
J, Dewulf   +6 more
openaire   +2 more sources

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