Results 151 to 160 of about 2,253,320 (247)

The Vasoactive Mas Receptor in Essential Hypertension. [PDF]

J Clin Med, 2020
Povlsen AL, Grimm D, Wehland M, Infanger M, Krüger M.   +4 more
europepmc   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Therapeutic potential of 20-Hydroxyecdysone in pulmonary arterial hypertension: involvement of Mas receptor and PI3K-Akt pathway. [PDF]

Cell Mol Biol Lett
Lu T, Jia W, Wang Y, Ma Y, Song C, Du F, Gao H, Jin X, Li H, Liu C, Jin H, Lin Y.   +11 more
europepmc   +1 more source

Activation of angiotensin-converting enzyme 2/angiotensin (1-7)/mas receptor axis triggers autophagy and suppresses microglia proinflammatory polarization via forkhead box class O1 signaling. [PDF]

Aging Cell, 2021
Dang R, Yang M, Cui C, Wang C, Zhang W, Geng C, Han W, Jiang P.   +7 more
europepmc   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Thrombosis Prevention without Anticoagulation

Frontiers in Medicine, 2014
Alvin H. Schmaier
doaj   +1 more source

Computational Discovery of Angiotensin-(1-7)-like Peptides Targeting the MAS Receptor from the Genomic Dark Matter of <i>Saccharomyces cerevisiae</i>. [PDF]

Int J Med Sci
Shidhi PR, Jayaprakash A, Raj N, Rajendran P, Ammar RB, Chellapan BV.   +5 more
europepmc   +1 more source

Angiotensin-(1-7) Prevents Lipopolysaccharide-Induced Autophagy via the Mas Receptor in Skeletal Muscle. [PDF]

Int J Mol Sci, 2020
Rivera JC, Abrigo J, Tacchi F, Simon F, Brandan E, Santos RA, Bader M, Chiong M, Cabello-Verrugio C.   +8 more
europepmc   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

ACE2/Angiotensin 1-7/Mas Receptor Axis in Thermogenic Adipose Tissue: Age-Related Implications for Pediatric Obesity. [PDF]

Pediatr Int
Mori J.
europepmc   +1 more source