The Potential of Multi-Screening Methods and Omics Technologies to Detect Both Regulated and Emerging Mycotoxins in Different Matrices [PDF]
Mycotoxins are well-known secondary metabolites produced by several fungi that grow and occur in different crops during both pre-harvest and post-harvest conditions.
Marco Lapris+3 more
doaj +2 more sources
Aspergillus Mycotoxins: The Major Food Contaminants. [PDF]
Mycotoxins produced by Aspergillus contaminate food products and threat to human health. The multifaceted biosynthesis pathways are first discussed and elucidated several global regulators of the mycotoxins in detail. How global shifts in temperature and water availability, driven by climate change, are key determinants of Aspergillus proliferation and
Xue M+23 more
europepmc +2 more sources
Probing the Interactions of 31 Mycotoxins with Xanthine Oxidase: Alternariol, Alternariol-3-Sulfate, and α-Zearalenol Are Allosteric Inhibitors of the Enzyme [PDF]
Mycotoxins are frequent toxic contaminants in foods and beverages, causing a significant health threat. Interactions of mycotoxins with biotransformation enzymes (e.g., cytochrome P450 enzymes, sulfotransferases, and uridine 5′-diphospho ...
Orsolya Balázs+5 more
doaj +2 more sources
Anomericity of T-2 Toxin-glucoside: Masked Mycotoxin in Cereal Crops [PDF]
T-2 toxin is a trichothecene mycotoxin produced when Fusarium fungi infect grains, especially oats and wheat. Ingestion of T-2 toxin contaminated grain can cause diarrhea, hemorrhaging, and feed refusal in livestock. Cereal crops infected with mycotoxin-producing fungi form toxin glycosides, sometimes called masked mycotoxins, which are a potential ...
Susan P. McCormick+9 more
openalex +5 more sources
Multi-Mycotoxin Contamination of Aquaculture Feed: A Global Survey [PDF]
Plant-based materials are increasingly being used as ingredients of aquaculture feed. These materials are prone to mycotoxin contamination, as mycotoxigenic fungi infest crop plants in the field and agricultural products during storage. As mycotoxins can
Christiane Gruber-Dorninger+2 more
doaj +2 more sources
Unveiling the Substrate-Dependent Dynamics of Mycotoxin Production in Fusarium verticillioides Using an OSMAC-Metabolomics Approach. [PDF]
Abstract Fusarium verticillioides is a prevalent plant pathogenic fungus known to produce harmful mycotoxins, including fumonisins and emerging toxins. This study aimed to investigate the influence of substrate on the temporal patterns of mycotoxin biosynthesis by F.
Groppi E+4 more
europepmc +2 more sources
Yesterday masked, today modified; what do mycotoxins bring next? [PDF]
Abstract Mycotoxins are secondary metabolites produced by toxigenic fungi in crops worldwide. In (micro)organisms such as plants, fungi, bacteria, or animals they may be further metabolised and modified, but this is also true for food processing, which may lead to a wide range of masked mycotoxin forms.
Marija Kovač+4 more
openalex +4 more sources
Intestinal toxicity of the masked mycotoxin deoxynivalenol-3-β-d-glucoside [PDF]
Natural food contaminants such as mycotoxins are an important problem for human health. Deoxynivalenol (DON) is one of the most common mycotoxins detected in cereals and grains. Its toxicological effects mainly concern the immune system and the gastrointestinal tract.
Alix Pierron+10 more
openalex +9 more sources
Metabolism of the masked mycotoxin deoxynivalenol-3-glucoside in pigs
Plants can metabolize the Fusarium mycotoxin deoxynivalenol (DON) by forming the masked mycotoxin deoxynivalenol-3-β-D-glucoside (D3G). D3G might be cleaved during digestion, thus increasing the total DON burden of an individual. Due to a lack of in vivo data, D3G has not been included in the various regulatory limits established for DON so far.
Veronika Nagl+6 more
openalex +3 more sources
Detached leafin vitro model for masked mycotoxin biosynthesis and subsequent analysis of unknown conjugates [PDF]
The manuscript details the development of anin vitro model plant system using detached leaves because there is a need for biosynthetic methods for the production and isolation of masked mycotoxins. This detached leafin vitro model was firstly applied to deoxynivalenol with satisfying results. The biosynthesis of deoxynivalenol-3-glucoside was confirmed
Marthe De Boevre+7 more
openalex +4 more sources