Results 151 to 160 of about 10,756,993 (383)
Meningioma represents the most frequent tumor of the central nervous system (CNS). Correlations between the presence of mast cells (MCs) and grade or other histological features of meningioma are still debated. Our study aimed to better understand the relationship between mast cells and meningiomas and to compare our results based on specific ...
D'amati A.+4 more
openaire +4 more sources
Immuno‐lung organoids are developed and used spatial transcriptomics to uncover how proinflammatory macrophages drive lung cell senescence via the THBS1–(ITGA3+ITGB1) axis in COVID‐19. To ensure broad accessibility, LungSpatialDB is created, an AI‐powered data portal, enabling intuitive exploration of spatial data and biological insights through ...
Yuling Han+24 more
wiley +1 more source
Sleep deprivation triggers systemic immune activation characterized by neutrophil accumulation and cytokine release. This study reveals a conserved metabolic‒epigenetic mechanism whereby lactate‐induced H3K18 lactylation upregulates RORα expression, promoting neutrophilic inflammation.
Ren Zhou+15 more
wiley +1 more source
Mast cell synapses and exosomes: membrane contacts for information exchange
In addition to their central role in allergy, mast cells are involved in a wide variety of cellular interactions during homeostasis and disease.
Amanda eCarroll-Portillo+4 more
doaj +1 more source
Akkermansia depletion correlates with acute pancreatitis (AP) severity. A. muciniphila and its protein Amuc_1409 mitigate pancreatic/systemic inflammation by expanding Tregs and IL‐10. Mechanistically, Amuc_1409 binds Ube2k, inhibiting Foxp3 ubiquitination to stabilize Treg differentiation and IL‐10 production, countering SAP‐induced SIRS/CARS ...
Jinyan Xie+9 more
wiley +1 more source
ELECTRON MICROSCOPY OF THE TISSUE MAST CELL [PDF]
Douglas E. Smith, Yevette S. Lewis
openalex +1 more source
The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis
This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen+6 more
wiley +1 more source
THE EFFECTS OF RESERPINE AND COMPOUND 48/80 ON THE RELEASE OF AMINES FROM THE MAST CELLS OF RATS [PDF]
B. K. Bhattacharya, G P Lewis
openalex +1 more source
Advances in Medical Devices for Augmented Acupuncture Therapy
Traditional acupuncture therapy faces several challenges in clinical applications, such as complex operation procedures and prolonged therapeutic periods. By incorporating physical stimulations and drug delivery technologies, engineered acupuncture needles (EANs) can enhance therapeutic efficacy, improve patient compliance, as well as mitigate ...
Ruisi Cai+7 more
wiley +1 more source