Results 61 to 70 of about 12,201,289 (252)

The Suppressive Activity of Fucofuroeckol-A Derived from Brown Algal Ecklonia stolonifera Okamura on UVB-Induced Mast Cell Degranulation

Marine Drugs, 2018
UV light, especially UVB, is known as a trigger of allergic reaction, leading to mast cell degranulation and histamine release. In this study, phlorotannin Fucofuroeckol-A (F-A) derived from brown algal Ecklonia stolonifera Okamura was evaluated for its ...
Thanh-Sang Vo, Se-Kwon Kim, Bomi Ryu, Dai-Hung Ngo, N. Yoon, L. Bach, Nguyen Thi Nhat Hang, Dai-Nghiep Ngo   +7 more
semanticscholar   +1 more source

Induction of Mast Cell Accumulation by Tryptase via a Protease Activated Receptor-2 and ICAM-1 Dependent Mechanism

Mediators of Inflammation, 2016
Mast cells are primary effector cells of allergy, and recruitment of mast cells in involved tissue is one of the key events in allergic inflammation. Tryptase is the most abundant secretory product of mast cells, but little is known of its influence on ...
Xin Liu, Junling Wang, Huiyun Zhang, Mengmeng Zhan, Hanqiu Chen, Zeman Fang, Chiyan Xu, Huifang Chen, Shaoheng He   +8 more
doaj   +1 more source

Involvement of Hypoxia-Inducible Factor-1 in the Inflammatory Responses of Human LAD2 Mast Cells and Basophils [PDF]

, 2012
We recently showed that hypoxia-inducible factor 1 (HIF-1) plays a crucial role in the pro-allergic functions of human basophils by transcriptional control of energy metabolism via glycolysis as well as directly triggering expression of the angiogenic ...
Claire L Streatfield, Sumbayev, Vadim V., Yasinska, Inna M., Gibbs, Bernhard F., Streatfield, Claire L., Vadim V Sumbayev, Oniku, Abraham E., Bernhard F Gibbs, Streatfield Claire L., Yasinska Inna, Sumbayev Vadim V., Inna Yasinska, Oniku Abraham E., Gibbs Bernhard F., Abraham E Oniku   +14 more
core   +1 more source

KIT mutation analysis in mast cell neoplasms: recommendations of the European competence network on mastocytosis [PDF]

, 2015
Although acquired mutations in KIT are commonly detected in various categories of mastocytosis, the methodologies applied to detect and quantify the mutant type and allele burden in cells and various tissues are poorly defined.
T. Haferlach, Reiter, A., Sperr, W. R., Akin, C, Valent, P., C. Akin, Garcia-Montero, A., G. Hoermann, Broesby-Olsen, S, Triggiani, M, Escribano, L, Hartmann, K.., Kluin-Nelemans, H. C., Cross, N.C.P., J. Gotlib, A. Reiter, Hermine, O., Akin, C., K. Sotlar, Haferlach, T, S. Broesby Olsen, Hoermann, G., TRIGGIANI, MASSIMO, P. Valent, A. Garcia Montero, Metcalfe, D. D., Sperr, W R, Broesby-Olsen, S., Gotlib, J, Kristensen, T. K., Arock, M, N. C. P. Cross, Schwaab, J., M. Arock, K. Hartmann, Schwaab, J, Metcalfe, D D, Escribano, L., O. Hermine, Kluin-Nelemans, H.C., Hermine, O, W. R. Sperr, J. Schwaab, Hoermann, G, Triggiani, M., Metcalfe, D.D., Cross, N C P, Horny, H.-P., Kluin-Nelemans, H C, Sotlar, K., D. D. Metcalfe, Sperr, W.R., Horny, H-P, Valent, P, Orfao, A., P. Dubreuil, Reiter, A, T. K. Kristensen, Orfao, A, Dubreuil, P., A. Orfao, Gotlib, J., L. Escribano, Sotlar, K, Kristensen, T.K., Hartmann, K., Cross, N. C. P., Haferlach, T., Dubreuil, P, Kielsgaard Kristensen, Thomas, Arock, M., Garcia-Montero, A, H. C. Kluin Nelemans, H. P. Horny, Hartmann, K   +74 more
core   +1 more source

Innate Immunity Induces the Accumulation of Lung Mast Cells During Influenza Infection

Frontiers in Immunology, 2018
Mast cells release disease-causing mediators and accumulate in the lung of asthmatics. The most common cause of exacerbations of asthma is respiratory virus infections such as influenza. Recently, we demonstrated that influenza infection in mice triggers
Behdad Zarnegar, Annika Westin, Syrmoula Evangelidou, Jenny Hallgren   +3 more
doaj   +1 more source

Pathways involved in gut mucosal barrier dysfunction induced in adult rats by maternal deprivation: corticotrophin-releasing factor and nerve growth factor interplay [PDF]

, 2007
Neonatal maternal deprivation (NMD) increases gut paracellular permeability (GPP) through mast cells and nerve growth factor (NGF), and modifies corticotrophin-releasing factor (CRF) and corticosterone levels.
Lionel Bueno, Ferrier, Laurent, Fioramonti, Jean, Mathilde Leveque, Cartier, Christel, Frederick Barreau, Raphael Moriez, Valerie Laroute, Laurent Ferrier, Andras Rosztoczy, Christel Cartier, Leveque, Mathilde, Rosztoczy, Andras, Jean Fioramonti, Barreau, Frederick, Laroute, Valerie, Moriez, Raphael, Bueno, Lionel   +17 more
core   +1 more source

Mast cells and mast cell tryptase enhance migration of human lung fibroblasts through protease-activated receptor 2

Cell Communication and Signaling, 2018
Mast cells may activate fibroblasts and contribute to remodeling processes in the lung. However, the mechanism behind these actions needs to be further investigated. Fibroblasts are major regulators of on-going remodeling processes.
Mariam Bagher, Anna-Karin Larsson-Callerfelt, O. Rosmark, O. Hallgren, L. Bjermer, G. Westergren-Thorsson   +5 more
semanticscholar   +1 more source

Nonpeptidergic neurons suppress mast cells via glutamate to maintain skin homeostasis

Cell, 2021
Summary Cutaneous mast cells mediate numerous skin inflammatory processes and have anatomical and functional associations with sensory afferent neurons.
Shiqun Zhang, T. Edwards, Virendra K. Chaudhri, Jianing Wu, Jonathan A. Cohen, T. Hirai, Natalie L. Rittenhouse, Elizabeth G. Schmitz, Paul Yifan Zhou, Benjamin D. McNeil, Yi Yang, H. Koerber, T. Sumpter, Amanda C. Poholek, B. Davis, K. Albers, Harinder Singh, D. Kaplan   +17 more
semanticscholar   +1 more source

Increased expression of formyl peptide receptor-1 by basophils from patients with mastocytosis

Journal of Allergy and Clinical Immunology: Global
Background: Symptoms in patients with systemic mastocytosis (SM) are associated with an increase in mast cell burden and release of mast cell–derived mediators.
Yuzhi Yin, MD, PhD, Jenny Min Li, PhD, Dean D. Metcalfe, MD, Ana Olivera, PhD, Pamela A. Frischmeyer-Guerrerio, MD, PhD, Melody C. Carter, MD, Hirsh Komarow, MD   +6 more
doaj   +1 more source

Mast cells and COPD [PDF]

Pulmonary Pharmacology & Therapeutics, 2011
The pathogenesis of chronic obstructive pulmonary disease (COPD) is based on the innate and adaptive inflammatory immune response to the inhalation of toxic particles and gases. Although tobacco smoking is the primary cause of this inhalation injury, many other environmental and occupational exposures contribute to the pathology of COPD.
Mortaz, E., Folkerts, G., Redegeld, F.A.M.   +2 more
openaire   +3 more sources