MiR-221 influences effector functions and actin cytoskeleton in mast cells. [PDF]
PLoS ONE, 2011 Mast cells have essential effector and immunoregulatory functions in IgE-associated allergic disorders and certain innate and adaptive immune responses, but the role of miRNAs in regulating mast cell functions is almost completely unexplored.
Ramon J Mayoral +6 more
doaj +1 more source
Mouse mast cell tryptase mMCP-6 is a critical link between adaptive and innate immunity in the chronic phase of Trichinella spiralis infection [PDF]
, 2008 Although the innate immune function of mast cells in the acute phase of parasitic and bacterial infections is well established, their participation in chronic immune responses to indolent infection remains incompletely understood.
Friend, Daniel S. +6 more
core +1 more source
Cellular Energetics of Mast Cell Development and Activation
Cells, 2021 Mast cells are essential first responder granulocytes in the innate immune system that are well known for their role in type 1 immune hypersensitivity reactions.
Ryan P. Mendoza +2 more
doaj +1 more source
Mast cell gastritis: Children complaining of chronic abdominal pain with histologically normal gastric mucosal biopsies except for increase in mast cells, proposing a new entity [PDF]
, 2009 Background Mast cells reside within the connective tissue of a variety of tissues and all vascularized organs. Since 1996, few studies have been performed on mast cell density in gastrointestinal biopsies, mainly in adult age group.
Fatemeh E Mahjoub +4 more
core +2 more sources
World Allergy Organization Journal, 2019 Background: Mast cells participate in immune responses by releasing potent immune system modifiers via degranulation. Due to currently reported controversial roles of mast cells in Streptococcus pneumoniae infections, this study aimed to determine the ...
Jing Yang +8 more
doaj +1 more source
Molecular Oncology, 2020 Mast cells are a major component of the immune microenvironment in tumour tissues and modulate tumour progression by releasing pro‐tumorigenic and antitumorigenic molecules.
Xuanwen Bao +3 more
doaj +1 more source
Interplay between mast cells, enterochromaffin cells, and sensory signaling in the aging human bowel. [PDF]
, 2009 BACKGROUND: Advanced age is associated with a reduction in clinical visceral pain perception. However, the underlying mechanisms remain largely unknown.
Firth +40 more
core +1 more source
Frontiers in Immunology, 2022 Mast cell hyperactivity and accumulation in tissues are associated with allergy and other mast cell-related disorders. However, the molecular pathways regulating mast cell survival in homeostasis and disease are not completely understood.
Guido Hernan Falduto +5 more
doaj +1 more source
Release of TNF-α during myocardial reperfusion depends on oxidative stress and is prevented by mast cell stabilizers [PDF]
, 2003 Objectives: Our study sought to elucidate the role of oxidative stress for shedding of tumor necrosis factor-α (TNF-α) and for activating TNF-α-converting enzyme (TACE).
Becker, Bernhard F. +4 more
core +1 more source
Chronic allergen challenge induces bronchial mast cell accumulation in BALB/c but not C57BL/6 mice and is independent of IL-9 [PDF]
, 2010 As genetically engineered mutant mice deficient in single genes are usually generated on a C57BL/6 background, to study mast cell trafficking in mutant mice, we initially investigated whether mast cells accumulated in bronchi in C57BL/6 mice challenged ...
Suzan Pae +5 more
core +2 more sources