Results 41 to 50 of about 10,588,551 (247)
Advanced Science, EarlyView.Migrasomes play a crucial role in endothelial‐immune interactions in atherosclerosis. This study identifies migrasomes as amplifiers in the inflammatory cascade, driving immune‐metabolic reprogramming via “migrasome‐APP‐CD74” signaling. Blocking CD74 disrupts migrasome‐mediated signaling, attenuating atherosclerosis progression.
Kangnan Zhang +10 more
wiley +1 more source
The Importance of Mast Cells in Dermal Scarring.
Advances in wound care, 2014 Significance: Mast cells are resident inflammatory cells present in high numbers in the skin. They are one of the first cell types to respond to damage and they do so by quickly releasing a variety of preformed mediators that are stored within mast cell ...
Traci A. Wilgus, Brian C. Wulff
semanticscholar +1 more source
Advanced Science, EarlyView.This study integrates scRNA‐seq, multiplex immunofluorescence, and clinical data to identify HLA‐DR⁺tumor cells uniquely enriched in Hepatocellular carcinoma (HCC) with hepatitis B virus (HBV). These cells express MHC II, associate with PD‐L1, recruit and exhaust CD8⁺T cells, predict poor survival, and serve as potential biomarkers for immunotherapy ...
Jun‐Qing Chang +17 more
wiley +1 more source
Advanced Science, EarlyView.This study extensively characterizes the B cell response of rainbow trout (Oncorhynchus mykiss) in response to red mark syndrome (RMS). This disease, suspected to be caused by a Midichloria‐like organism (MLO), induces skin lesions in the infected animals, characterized by a massive influx of IgM+ B cells.
J Germán Herranz‐Jusdado +10 more
wiley +1 more source
Blood, 2016 Mast cells are rare tissue-resident immune cells that are involved in allergic reactions, and their numbers are increased in the lungs of asthmatics.
Joakim S. Dahlin +6 more
semanticscholar +1 more source
Bidirectional Interaction Between the Brain and Bone in Traumatic Brain Injury
Advanced Science, EarlyView.Traumatic brain injury (TBI) disrupts the blood–brain barrier and activates neuroimmune responses, causing metabolic disturbances and long‐term bone mass loss. Concurrent fractures accelerate healing and enhance osteogenesis but disrupt regulatory mechanisms, leading to altered bone dynamics and exacerbating neuroinflammation, complicating recovery ...
Wei Zhang, Jun Zou, Lingli Zhang
wiley +1 more source
MAST CELLS OF THE OMENTUM IN RELATION TO STATES OF ADRENOCORTICAL DEFICIENCY AND EXCESS [PDF]
, 1953 Burton L. Baker
openalex +1 more source
Structural Variations Associated with Adaptation and Coat Color in Qinghai‐Tibetan Plateau Cattle
Advanced Science, EarlyView.This study reveals the landscape of structural variants in Qinghai‐Tibetan Plateau cattle through long‐read sequencing. Discoveries include metabolic and oxygen‐regulation gene variants, along with a 2‐Mb KIT‐containing inversion and translocations responsible for cattle gray coat. These findings highlight the significant role of structural variants in
Xiaoting Xia +39 more
wiley +1 more source
Advanced Science, EarlyView.Immuno‐lung organoids are developed and used spatial transcriptomics to uncover how proinflammatory macrophages drive lung cell senescence via the THBS1–(ITGA3+ITGB1) axis in COVID‐19. To ensure broad accessibility, LungSpatialDB is created, an AI‐powered data portal, enabling intuitive exploration of spatial data and biological insights through ...
Yuling Han +24 more
wiley +1 more source
Relation of Mastocytoma to Mast Cell Leukemia, and of Heparin, Histamine and Serotonin to Mast Cells [PDF]
, 1959 Saburo Ono +3 more
openalex +1 more source