Results 41 to 50 of about 143,658 (169)

Distribution of ghrelin-positive mast cells in rat stomach

Biotechnology & Biotechnological Equipment, 2017
It is known that the gastrointestinal peptide hormone ghrelin is expressed in human and rodent B lymphocytes, T lymphocytes, monocytes and natural killer cells. However, there are no data about ghrelin expression by mast cells.
Ivaylo Stefanov Stefanov, Julian Rumenov Ananiev, Koni Vancho Ivanova, Anna Naidenova Tolekova, Angel Petrov Vodenicharov, Maya Vladova Gulubova   +5 more
doaj   +1 more source

Mast Cell Regulation of the Immune Response

World Allergy Organization Journal, 2009
Mast cells are well known as principle effector cells of type I hypersensitivity responses. Beyond this role in allergic disease, these cells are now appreciated as playing an important role in many inflammatory conditions.
John J. Ryan, MD, Johanna K. Morales, MD, Yves T. Falanga, MD, Josephine F.A. Fernando, MD, Matthew R. Macey   +4 more
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Interaction of primary mast cells with Borrelia burgdorferi (sensu stricto): role in transmission and dissemination in C57BL/6 mice

Parasites & Vectors, 2017
Background Borrelia burgdorferi (sensu lato), the causative agent of Lyme borreliosis is a bacterium transmitted by hard ticks, Ixodes spp. Bacteria are injected into the host skin during the tick blood meal with tick saliva.
Quentin Bernard, Zhenping Wang, Anna Di Nardo, Nathalie Boulanger   +3 more
doaj   +1 more source

Limited role of mast cells during infection with the parasitic nematode Litomosoides sigmodontis.

PLoS Neglected Tropical Diseases, 2020
Mast cells are innate effector cells that due to their localization in the tissue form the first line of defense against parasites. We have previously shown that specifically mucosal mast cells were essential for the termination of the intestinal ...
Lara Christine Linnemann, Martina Reitz, Thorsten B Feyerabend, Minka Breloer, Wiebke Hartmann   +4 more
doaj   +1 more source

Induction of Mast Cell Accumulation by Tryptase via a Protease Activated Receptor-2 and ICAM-1 Dependent Mechanism

Mediators of Inflammation, 2016
Mast cells are primary effector cells of allergy, and recruitment of mast cells in involved tissue is one of the key events in allergic inflammation. Tryptase is the most abundant secretory product of mast cells, but little is known of its influence on ...
Xin Liu, Junling Wang, Huiyun Zhang, Mengmeng Zhan, Hanqiu Chen, Zeman Fang, Chiyan Xu, Huifang Chen, Shaoheng He   +8 more
doaj   +1 more source

Single-cell analysis reveals the KIT D816V mutation in haematopoietic stem and progenitor cells in systemic mastocytosisResearch in context

EBioMedicine, 2019
Background: Systemic mastocytosis (SM) is a haematological disease characterised by organ infiltration by neoplastic mast cells. Almost all SM patients have a mutation in the gene encoding the tyrosine kinase receptor KIT causing a D816V substitution and
Jennine Grootens, Johanna S. Ungerstedt, Maria Ekoff, Elin Rönnberg, Monika Klimkowska, Rose-Marie Amini, Michel Arock, Stina Söderlund, Mattias Mattsson, Gunnar Nilsson, Joakim S. Dahlin   +10 more
doaj   +1 more source

Leptin deficiency-induced obesity affects the density of mast cells in abdominal fat depots and lymph nodes in mice

Lipids in Health and Disease, 2012
Background Mast cells are implicated in the pathogenesis of obesity and insulin resistance. Here, we explored the effects of leptin deficiency-induced obesity on the density of mast cells in metabolic (abdominal fat depots, skeletal muscle, and liver ...
Altintas Mehmet M, Nayer Behzad, Walford Eric C, Johnson Kevin B, Gaidosh Gabriel, Reiser Jochen, De La Cruz-Munoz Nestor, Ortega Luis M, Nayer Ali   +8 more
doaj   +1 more source

Comparative Evaluation of Mast Cells in Lichen Planus and Oral Lichenoid Reaction with Giemsa Staining [PDF]

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd
Introduction: Lichen planus is a relatively common and chronic mucocutaneous disease with unknown. Oral lichenoid reaction is clinical and histopathological similar to lichen planus, but the cause of it is different.
Najmeh Jafari, Seyed Mostafa Mahmoudi, Mohamad Bagher Lajevardi   +2 more
doaj  

Mast Cells Stimulated with Peptidoglycan from Staphylococcus aureus Augment the Development of Th1 Cells

Journal of Pharmacy & Pharmaceutical Sciences, 2018
Background: The skin of patients with atopic dermatitis (AD) is superficially colonized by Staphylococcus aureus. We have previously found that percutaneous permeation of peptidoglycan (PEG) from S. aureus increases the number of mast cells in the dermis,
Katsuhiko Matsui, Saeko Kanai, Manami Ikuta, Saki Horikawa   +3 more
doaj   +1 more source

CXCL6-CXCR2 axis-mediated PD-L2+ mast cell accumulation shapes the immunosuppressive microenvironment in osteosarcoma

Heliyon
Osteosarcoma (OS) is the most common primary bone malignancy and has a high propensity for local invasion and metastasis. The tumour microenvironment of OS is infiltrated by a large number of immune cells, which play a crucial role in its progression and
Chengguang Wang, Zhenbin Lei, Chuanzhi Zhang, Xiaobo Hu   +3 more
doaj   +1 more source