Results 61 to 70 of about 11,909 (199)

Relapse of Acute Myeloid Leukemia With Concomitant Systemic Mastocytosis Five Years Post Allogenic Hematopoietic Stem Cell Transplantation

Case Reports in Hematology, Volume 2026, Issue 1, 2026.
Systemic mastocytosis (SM) with associated hematological neoplasia (SM‐AHN) is a rare and aggressive condition characterized by abnormal clonal proliferation of mast cells and the concurrent occurrence of hematologic malignancies, such as acute myeloid leukemia (AML).
Sona Vardanyan, Hilde K. Gjelberg, Lars Helgeland, Galina Tsykunova, Rakel Brendsdal Forthun, Håkon Reikvam, Stephen E. Langabeer   +6 more
wiley   +1 more source

Bullous mastocytosis

Indian Journal of Dermatology, 2007
Mastocytosis is a condition characterized by the disorderly infiltration of mast cells in several tissues and comprises many different clinical situations varying from indolent cutaneous forms to malignant and systemic conditions. Bullous mastocytosis is
Nayak Surajit, Acharjya Basanti, Devi Basanti, Behera Samira   +3 more
doaj  

Challenges in the Diagnosis of Cutaneous Mastocytosis

Diagnostics
Background: Mastocytosis is characterized by an accumulation of clonal mast cells (MCs) in tissues such as the skin. Skin lesions in mastocytosis may be clinically subtle or heterogeneous, and giving the correct diagnosis can be difficult.
Knut Brockow, Rebekka Karolin Bent, Simon Schneider, Sophie Spies, Katja Kranen, Benedikt Hindelang, Zsuzsanna Kurgyis, Sigurd Broesby-Olsen, Tilo Biedermann, Clive E. Grattan   +9 more
doaj   +1 more source

An Adult Patient with Systemic Mastocytosis and B-Acute Lymphoblastic Leukemia

Case Reports in Medicine, 2014
Mastocytosis is a myeloproliferative neoplasm characterized by clonal expansion of abnormal mast cells, ranging from the cutaneous forms of the disease to mast cell leukemia.
Theodoros Iliakis, Niki Rougkala, Panagiotis T. Diamantopoulos, Vasiliki Papadopoulou, Fani Kalala, Konstantinos Zervakis, Nefeli Giannakopoulou, Polixeni Chatzinikolaou, Georgia Levidou, Eleftheria Lakiotaki, Penelope Korkolopoulou, Efstratios Patsouris, Eleni Variami, Nora-Athina Viniou   +13 more
doaj   +1 more source

Systemic Mastocytosis - a Diagnostic Challenge [PDF]

, 2014
Mastocytosis refers to a group of disorders characterized by the infiltration of clonally derived mast cells to the skin or extracutaneous tissues resulting in a heterogeneous clinical picture. It is a rare hematologic disorder in all its forms.
Galzerano, A, Lladó, AC, Mihon, C, Silva, M   +3 more
core  

Tissue‐Resident Myeloid and Histiocytic Cells in Health and Disease: Novel Emerging Concepts

American Journal of Hematology, Volume 100, Issue 12, Page 2305-2319, December 2025.
ABSTRACT Although all myeloid cells are considered to derive from hematopoietic stem cells, the cells in each myeloid lineage are heterogeneous populations, and their distribution and functions vary, depending on underlying physiologic and pathologic processes, age, sex, and genetic and epigenetic signatures.
Peter Valent, Johann Wojta, Petri T. Kovanen, Olivier Hermine, Falko Fend, Karl Sotlar, Hildegard Greinix, Klaus Geissler, Karin Hartmann, Juliana Schwaab, Marco Herling, Laura Boccuni, Lukas Kazianka, Max Vincent John, Wolfgang R. Sperr, Carina Zierfuss, Alexandar Tzankov, Christian Sillaber, Milen Minkov, Gregor Hoermann, Matthew Collin, Hans‐Peter Horny, Torsten Haferlach, Maria Sibilia, Julien Haroche, Paul La Rosée, Alberto Orfao, Michel Arock   +27 more
wiley   +1 more source

Cutaneous and Gastrointestinal Symptoms in Two Patients with Systemic Mastocytosis Successfully Treated with Omalizumab

Case Reports in Medicine, 2015
The pathogenesis of mastocytosis is not well defined and thus treatment remains challenging and remains on a palliative basis. We present two cases (a 48-year-old woman and a 57-year-old man) with indolent systemic mastocytosis in whom omalizumab (anti ...
Sofie Lieberoth, Simon Francis Thomsen
doaj   +1 more source

Mastocytosis: One Word for Different Diseases

Oncology and Therapy, 2018
Mastocytosis is a neoplastic disease originating from tissue infiltration by transformed mast cells. The diagnosis requires a high grade of suspicion due to the large variety of presenting symptoms. The World Health Organization classification recognizes
Marianna Criscuolo, Luana Fianchi, Alessio M. E. Maraglino, Livio Pagano   +3 more
doaj   +1 more source

Allergen-specific immunotherapy of Hymenoptera venom allergy:also a matter of diagnosis [PDF]

, 2015
Stings of hymenoptera can induce IgE-mediated hypersensitivity reactions in venom-allergic patients, ranging from local up to severe systemic reactions and even fatal anaphylaxis.
Schiener, Maximilian, Graessel, Anke, Ollert, Markus, Schmidt-Weber, Carsten B, Blank, Simon   +4 more
core   +2 more sources

Beyond the numbers: Critical analysis of the role of postmortem tryptase in the forensic diagnosis of anaphylaxis

Journal of Forensic Sciences, Volume 70, Issue 6, Page 2117-2128, November 2025.
Abstract The postmortem diagnosis of anaphylaxis remains a forensic challenge due to the lack of specific external signs. Tryptase, a mast cell‐derived protease, has emerged as a potential biomarker for fatal anaphylaxis. This systematic review critically examined 40 studies published between 2014 and 2024, including both biochemical and ...
Luca Tomassini, Giulia Ricchezze, Cristiana Gambelunghe, Massimo Lancia, Marco Gramaccia, Francesco De Micco, Piergiorgio Fedeli, Mariano Cingolani, Roberto Scendoni   +8 more
wiley   +1 more source