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M6P-modified solid lipid nanoparticles loaded with matrine for the treatment of fibrotic liver
Liver fibrosis is a key pathological process shared by the progression of various chronic liver diseases. Treatment of liver fibrosis can effectively block the occurrence and development of hepatic cirrhosis or even carcinoma.
Xiaochuan Tan +8 more
semanticscholar +1 more source
Matrine is an efficient, low-toxicity, and environmentally friendly botanical pesticide; however, it is mainly applied as a soluble concentrate (SL) with a limited utilization rate that is unsuitable for ultra-low-volume spraying and unmanned aerial ...
Meng Li +5 more
doaj +1 more source
A Hexa-Herbal TCM Decoction Used to Treat Skin Inflammation: An LC-MS-Based Phytochemical Analysis [PDF]
In order to understand the chemical relationship between a traditional hexa-herbal Chinese medicine formula and botanical drugs it is derived from, an analytical platform comprising liquid chromatography coupled with triple quadrupole mass spectrometry ...
Chang, JB +3 more
core +1 more source
Atopic dermatitis (AD) is a common inflammatory skin disease. Matrine is the main component of the traditional Chinese medicine Sophora flavescens, and it poses good therapeutic effects on inflammatory diseases.
Pan Huang +7 more
semanticscholar +1 more source
Matrin 3 Binds and Stabilizes mRNA
Matrin 3 (MATR3) is a highly conserved, inner nuclear matrix protein with two zinc finger domains and two RNA recognition motifs (RRM), whose function is largely unknown. Recently we found MATR3 to be phosphorylated by the protein kinase ATM, which activates the cellular response to double strand breaks in the DNA. Here, we show that MATR3 interacts in
Salton, M. +6 more
openaire +5 more sources
Background Matrine, a traditional Chinese medicine, has recently been shown to have antitumor properties in diverse cancer cells. Here, we explored the effect of matrine on human glioblastoma multiforme (GBM) cells.
Wenjing Zhou +11 more
doaj +1 more source
Novel matrine derivative MD-1 attenuates hepatic fibrosis by inhibiting EGFR activation of hepatic stellate cells [PDF]
Matrine (MT), the effective component of Sophora flavescens Ait, has been shown to have anti-inflammation, immune-suppressive, anti-tumor, and anti-hepatic fibrosis activities.
Hai-yan Ying +5 more
core +2 more sources
Hepatitis C: From inflammatory pathogenesis to anti-inflammatory/hepatoprotective therapy [PDF]
Hepatitis C virus (HCV) infection commonly causes progressive liver diseases that deteriorate from chronic inflammation to fibrosis, cirrhosis and even to hepatocellular carcinoma.
Huang, Meng-Hao +3 more
core +2 more sources
Our previous studies demonstrated that matrine directly acts on the replication process of porcine reproductive and respiratory syndrome virus (PRRSV). Matrine inhibits viral replication and is also associated with the NF-κB signalling pathway.
Panpan Sun +8 more
doaj +1 more source
Reduced graphene oxide-Nafion composite modified glassy carbon electrode (RGO-Nafion/GCE) was prepared and the electrochemical behavior of matrine at RGO-Nafion/GCE was investigated by cyclic voltammetry (CV) and differential pulse voltammetry (DPV).
Hongjiao Zhang +6 more
doaj +1 more source

