Results 41 to 50 of about 9,281 (250)

M6P-modified solid lipid nanoparticles loaded with matrine for the treatment of fibrotic liver

open access: yesDrug Delivery, 2023
Liver fibrosis is a key pathological process shared by the progression of various chronic liver diseases. Treatment of liver fibrosis can effectively block the occurrence and development of hepatic cirrhosis or even carcinoma.
Xiaochuan Tan   +8 more
semanticscholar   +1 more source

Formulation of Matrine Oil-Based Suspension Concentrate for Improving the Wetting of Droplets and Spraying Performance

open access: yesAgronomy, 2023
Matrine is an efficient, low-toxicity, and environmentally friendly botanical pesticide; however, it is mainly applied as a soluble concentrate (SL) with a limited utilization rate that is unsuitable for ultra-low-volume spraying and unmanned aerial ...
Meng Li   +5 more
doaj   +1 more source

A Hexa-Herbal TCM Decoction Used to Treat Skin Inflammation: An LC-MS-Based Phytochemical Analysis [PDF]

open access: yes, 2016
In order to understand the chemical relationship between a traditional hexa-herbal Chinese medicine formula and botanical drugs it is derived from, an analytical platform comprising liquid chromatography coupled with triple quadrupole mass spectrometry ...
Chang, JB   +3 more
core   +1 more source

Matrine regulates Th1/Th2 inflammatory responses by inhibiting the Hsp90/NF‐κB signaling axis to alleviate atopic dermatitis

open access: yesKaohsiung Journal of Medical Sciences, 2023
Atopic dermatitis (AD) is a common inflammatory skin disease. Matrine is the main component of the traditional Chinese medicine Sophora flavescens, and it poses good therapeutic effects on inflammatory diseases.
Pan Huang   +7 more
semanticscholar   +1 more source

Matrin 3 Binds and Stabilizes mRNA

open access: yesPLoS ONE, 2011
Matrin 3 (MATR3) is a highly conserved, inner nuclear matrix protein with two zinc finger domains and two RNA recognition motifs (RRM), whose function is largely unknown. Recently we found MATR3 to be phosphorylated by the protein kinase ATM, which activates the cellular response to double strand breaks in the DNA. Here, we show that MATR3 interacts in
Salton, M.   +6 more
openaire   +5 more sources

Matrine induces senescence of human glioblastoma cells through suppression of the IGF1/PI3K/AKT/p27 signaling pathway

open access: yesCancer Medicine, 2018
Background Matrine, a traditional Chinese medicine, has recently been shown to have antitumor properties in diverse cancer cells. Here, we explored the effect of matrine on human glioblastoma multiforme (GBM) cells.
Wenjing Zhou   +11 more
doaj   +1 more source

Novel matrine derivative MD-1 attenuates hepatic fibrosis by inhibiting EGFR activation of hepatic stellate cells [PDF]

open access: yes, 2016
Matrine (MT), the effective component of Sophora flavescens Ait, has been shown to have anti-inflammation, immune-suppressive, anti-tumor, and anti-hepatic fibrosis activities.
Hai-yan Ying   +5 more
core   +2 more sources

Hepatitis C: From inflammatory pathogenesis to anti-inflammatory/hepatoprotective therapy [PDF]

open access: yes, 2018
Hepatitis C virus (HCV) infection commonly causes progressive liver diseases that deteriorate from chronic inflammation to fibrosis, cirrhosis and even to hepatocellular carcinoma.
Huang, Meng-Hao   +3 more
core   +2 more sources

Matrine inhibits IL-1β secretion in primary porcine alveolar macrophages through the MyD88/NF-κB pathway and NLRP3 inflammasome

open access: yesVeterinary Research, 2019
Our previous studies demonstrated that matrine directly acts on the replication process of porcine reproductive and respiratory syndrome virus (PRRSV). Matrine inhibits viral replication and is also associated with the NF-κB signalling pathway.
Panpan Sun   +8 more
doaj   +1 more source

Electrochemical Behavior and Determination of Matrine by the Reduced Graphene Oxide-Nafion Modified Glassy Carbon Electrode

open access: yesInternational Journal of Electrochemical Science, 2015
Reduced graphene oxide-Nafion composite modified glassy carbon electrode (RGO-Nafion/GCE) was prepared and the electrochemical behavior of matrine at RGO-Nafion/GCE was investigated by cyclic voltammetry (CV) and differential pulse voltammetry (DPV).
Hongjiao Zhang   +6 more
doaj   +1 more source

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