Results 61 to 70 of about 386,755 (358)
Dynamic DNA methylation of matrix metalloproteinase-9 in the development of diabetic retinopathy
Laboratory Investigation, 2016 Diabetes elevates matrix metalloproteinase-9 (MMP-9) in the retina and its capillary cells, and activated MMP-9 damages mitochondria, accelerating retinal capillary cell apoptosis, a phenomenon which precedes the development of retinopathy. Diabetes also
R. Kowluru, Yang Shen, Manish Mishra
semanticscholar +1 more source
Matrix Metalloproteinase 9 in Epilepsy: The Role of Neuroinflammation in Seizure Development
Mediators of Inflammation, 2016 Matrix metalloproteinase 9 is a proteolytic enzyme which is recently one of the more often studied biomarkers. Its possible use as a biomarker of neuronal damage in stroke, heart diseases, tumors, multiple sclerosis, and epilepsy is being widely ...
E. Bronisz, I. Kurkowska-Jastrzębska
semanticscholar +1 more source
Matrix metalloproteinase 9 gene-MMP9-DNA methylation status in Turkish schizophrenia patients
Türk Biyokimya Dergisi, 2023 Schizophrenia is a neuropsychiatric disease caused by disorders in brain development due to genetic and environmental factors. The interactions and mechanisms of the two main etiological factors are not fully understood despite neurobiological, clinical ...
Karaaslan Ezgi +3 more
doaj +1 more source
Asthma remodeling: The pathogenic role of matrix metalloproteinase-9
Egyptian Journal of Chest Disease and Tuberculosis, 2014 Background: Asthma is an airway inflammatory disease with functional and structural changes, leading to bronchial hyperresponsiveness and airflow obstruction.
Amgad A. Farhat +5 more
doaj +1 more source
Alimentary Pharmacology and Therapeutics, 2016 Matrix metalloproteinase‐9 is a proteolytic enzyme whose expression is increased in ulcerative colitis.
W. Sandborn +20 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Pakistan Journal of Medicine and DentistryBackground: Fibrotic lung diseases were seen to have devastating effects among patients globally. Matrix metalloproteinases (MMP) including MMP-7, MMP-9, and MMP-1 have become promising biomarkers for idiopathic pulmonary fibrosis (IPF), and other ...
Mehvish Aqil +6 more
doaj +1 more source
Gene Polymorphism of Matrix Metalloproteinase 9 in Asthenozoospermic Male Subjects [PDF]
International Journal of Fertility and Sterility, 2018 Background: Matrix metalloproteinase (MMPs) play important roles in the structural and functional properties of reproductive organs. The aim of this study is to determine the prevalence of C-1562T MMP-9 (rs3918242) gene polymorphism in fertile and ...
Sina Mohagheghi +4 more
doaj +1 more source
The Role of MMP-9 and MMP-9 Inhibition in Different Types of Thyroid Carcinoma
Molecules, 2023 Matrix metalloproteinase-9 (MMP-9), one of the most investigated and studied biomarkers of the MMPs family, is a zinc-dependent proteolytic metalloenzyme whose primary function is degrading the extracellular matrix (ECM).
Zhenshengnan Li +6 more
doaj +1 more source
Matrix metalloproteinase-9 as a biomarker predicting male fertility [PDF]
, 2016 The paper discusses the study of matrix metalloproteinase-9 (ММР-9) content in ejaculate after the hernia repair surgery. The clinical research study is based upon the results of inguinal hernia repair in 68 male patients at the age from 18 to 40.
Magomedbekov, R. E., Magomedov, M. M.
core +2 more sources